Signalling and Transport in Epithelia
Our general aim is to understand the epithelial transport processes and their regulation at the molecular/cellular level and to integrate these into the normal physiological function of the chosen organs and the body. Pancreas is one of the organs of interest, and further goals are to understand how these transport processes play roles in pathophysiology of pancreas cancer, cystic fibrosis, pancreatitis and diabetes.
Current research includes projects on the role of extracellular ATP and purinergic signalling in regulation of acid/base, chloride, potassium and calcium transport in health and disease of pancreatic and other cells. We use many techniques, especially advanced bioimaging in our new center.