The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskning

Standard

The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. / Gilbert, Lawrence; Rewitz, Kim.

The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. Springer Science+Business Media, 2009. s. 231.

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskning

Harvard

Gilbert, L & Rewitz, K 2009, The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. i The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. Springer Science+Business Media, s. 231.

APA

Gilbert, L., & Rewitz, K. (2009). The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. I The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions (s. 231). Springer Science+Business Media.

Vancouver

Gilbert L, Rewitz K. The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. I The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. Springer Science+Business Media. 2009. s. 231

Author

Gilbert, Lawrence ; Rewitz, Kim. / The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions. Springer Science+Business Media, 2009. s. 231

Bibtex

@inbook{1ea9e597956e478ba8f060e3a21bb486,
title = "The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions",
abstract = "The Halloween genes of Drosophila melanogaster were first described in the 1980s using cytogenetic methodology. During the past several years the genes have been cloned, expressed and the gene products have been characterized as cytochrome P450 enzymes (CYPs) and four have been functionalized as mediating the final steps in the biosynthesis of the arthropod molting hormone, 20-hydroxyecdysone (20E). A fifth has now been studied in detail and shown to be required for ecdysteroidogenesis but its exact function has yet to be elucidated. Since both insects and crustaceans utilize 20E as their principal molting hormone we have examined by BLAST search the genome of Daphnia and demonstrated the existence of Halloween gene orthologs in this crustacean, indicating that these genes play an identical role in this class as they do in insects. Further examination of the data bases representing Lepidoptera, Coleoptera, Hymenoptera and other Diptera allowed the development of a phylogenetic scheme for this gene family and suggests that the Halloween genes and vertebrate steroidogenic P450s originated from common ancestors that were perhaps destined for steroidogenesis, and arose before the deuterostome-arthropod split.",
author = "Lawrence Gilbert and Kim Rewitz",
year = "2009",
language = "English",
pages = "231",
booktitle = "The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions",
publisher = "Springer Science+Business Media",
address = "Singapore",

}

RIS

TY - CHAP

T1 - The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions

AU - Gilbert, Lawrence

AU - Rewitz, Kim

PY - 2009

Y1 - 2009

N2 - The Halloween genes of Drosophila melanogaster were first described in the 1980s using cytogenetic methodology. During the past several years the genes have been cloned, expressed and the gene products have been characterized as cytochrome P450 enzymes (CYPs) and four have been functionalized as mediating the final steps in the biosynthesis of the arthropod molting hormone, 20-hydroxyecdysone (20E). A fifth has now been studied in detail and shown to be required for ecdysteroidogenesis but its exact function has yet to be elucidated. Since both insects and crustaceans utilize 20E as their principal molting hormone we have examined by BLAST search the genome of Daphnia and demonstrated the existence of Halloween gene orthologs in this crustacean, indicating that these genes play an identical role in this class as they do in insects. Further examination of the data bases representing Lepidoptera, Coleoptera, Hymenoptera and other Diptera allowed the development of a phylogenetic scheme for this gene family and suggests that the Halloween genes and vertebrate steroidogenic P450s originated from common ancestors that were perhaps destined for steroidogenesis, and arose before the deuterostome-arthropod split.

AB - The Halloween genes of Drosophila melanogaster were first described in the 1980s using cytogenetic methodology. During the past several years the genes have been cloned, expressed and the gene products have been characterized as cytochrome P450 enzymes (CYPs) and four have been functionalized as mediating the final steps in the biosynthesis of the arthropod molting hormone, 20-hydroxyecdysone (20E). A fifth has now been studied in detail and shown to be required for ecdysteroidogenesis but its exact function has yet to be elucidated. Since both insects and crustaceans utilize 20E as their principal molting hormone we have examined by BLAST search the genome of Daphnia and demonstrated the existence of Halloween gene orthologs in this crustacean, indicating that these genes play an identical role in this class as they do in insects. Further examination of the data bases representing Lepidoptera, Coleoptera, Hymenoptera and other Diptera allowed the development of a phylogenetic scheme for this gene family and suggests that the Halloween genes and vertebrate steroidogenic P450s originated from common ancestors that were perhaps destined for steroidogenesis, and arose before the deuterostome-arthropod split.

M3 - Book chapter

SP - 231

BT - The Function and Evolution of the Halloween Genes; the Pathway to the Arthropod Molting Hormone. In Ecdysone, Structures and Functions

PB - Springer Science+Business Media

ER -

ID: 43665466