At the Department of Biology, University of Copenhagen, we have established the Linderstrøm-Lang Centre for Protein Science to carry on in the tradition of Kaj Ulrik Linderstrøm-Lang and to address some of the questions which after 60 years are still left fundamentally unanswered:
- How do proteins attain their functionality?
- What role does dynamics play in protein function and how is this interplay comprehensively described and predicted?
- How do cells regulate the life cycle of a protein from synthesis to degradation?
- Can we use this knowledge to design new enzymes with new activities?
The questions are addressed by applying sophisticated methods through projects spanning the realms of fundamental and applied science.
JBC Virtual Issue
A publication from the Linderstrøm-Lang Centre hosted at the Section for Biomolecular Sciences has been included in the JBC virtual issue on structural biology. The paper describes how elusive but widespread disordered short linear motifs can provide a key to mapping the interactome of transcription factors.