Welcome to the Hartmann-Petersen lab website! Here, you may find information about ongoing research projects, the research group, open positions and how to contact us.
Our research activity is primarily centered on intracellular protein degradation via the ubiquitin-proteasome pathway. The ubiquitin-proteasome system is highly conserved and is the major pathway for intracellular proteolysis in all eukaryotic cells. Accordingly, ubiquitin-dependent protein degradation plays a pivotal role in the turnover of key regulatory proteins involved in a series of cellular processes, including cell cycle control, signal transduction, and protein folding. For a number of years a focus area for us has been how abnormal or misfolded proteins are targeted for degradation. To this end, we use fission yeast and mammalian cells in tissue culture as model systems, combined with a series of genetic, biochemical and molecular cell biological methods. In addition, we collaborate closely with a number of other research groups both in Denmark and abroad.
If you are interested to learn more or join the lab, please contact Rasmus directly via e-mail.
University of Copenhagen
Ole Maaloes Vej 5, room 3-2-41
DK-2200 Copenhagen N