Research in the Protein Design and Enzymology Group
Click on the names to learn more about the research in the individual laboratories.
Kresten Lindorff-LarsenThe primary tools used in our research are computational methods that we use to study the structure and dynamics of proteins. A particular focus is methods that combine experimental data from NMR spectroscopy with molecular simulations.
Martin WillemoësOur work includes elucidating the mechanism of catalysis and regulation for enzymes involved in complex polysaccharide degradation (amylase, mutanase and alpha-mannosidase), for proteases (HIV protease), antibiotic resistance conferring enzymes like beta-lactamase and small molecule converting enzymes mainly from nucleotide metabolism.
Jakob Rahr WintherMy scientific work is focused on basic aspects of protein chemistry and using molecular biology and molecular genetics to understand structure-function relationships in proteins. The main areas of experience include disulfide bond formation and thiol-disulfide redox reactions, in particular in a chemical/biophysical setting with a strong focus on in vitro characterization.