Transfer of antibiotic resistance in human pathogens
|Target group:||Biology, Molecular Biomedicine, Biochemistry|
Staphylococcus aureus is a serious human pathogen and the methicillin resistant strains, the MRSAs, are a growing problem in human infections which can be acquired in hospitals, in the community or from farm animals known as “pig MRSA”. Bacterial viruses, the bacteriophages (phages), are important for host specificity of MRSA and recently we have demonstrated that lysogenic phages enable staphylococcal strains to acquire antibiotic resistance genes in part explaining why S. aureus strains so easily become resistant to antibiotics (Haaber et al. Nature Communications, 7: 13333, 2016).
Are you interested in working with S. aureus, MRSA and the role of phages in transfer of antibiotic resistance genes and host specificity? And are you interested in doing it in a collaboration between two UCPH departments? Then we might have a master thesis project for you addressing some of the following questions:
|Supervisor(s):||Hanne Ingmer (HI@sund.ku.dk) and Sine Lo Svenningsen (SLS@bio.ku.dk)|