Regenberg Lab – Department of Biology - University of Copenhagen

Cells respond to environmental changes through physiological adaptation at the short term level and adaptive evolution at the long term level.

Our research is focused on physiological adaptation and adaptive evolution of the eukaryotic cell to nutrient availability. For this the yeast, S. cerevisiae is used as model to study:

  1. Adaptation of yeast to nitrogen limitation
  2. Molecular mechanisms for yeast biofilm development
  3. Development of drug resistance
  4. Extrachromosomal DNA elements

Methods applied to investigate adaptations are sequencing and DNA array based global studies of the transcriptome and genome; metabolic engineering; Confocal Laser Scanning Microscopy as well as classical methods in fermentation, biochemistry, molecular biology and genetics.