Mathias Middelboe

Mathias Middelboe

Professor


  1. 2023
  2. Published

    Hydrostatic pressure induces transformations in the organic matter and microbial community composition of marine snow particles

    Stief, P., Schauberger, C., Becker, K. W., Elvert, M., Balmonte, J. P., Franco-Cisterna, B., Middelboe, Mathias & Glud, R. N., 2023, In: Communications Earth and Environment. 4, 1, 14 p., 377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Staying below the Radar: Unraveling a New Family of Ubiquitous “Cryptic” Non-Tailed Temperate Vibriophages and Implications for Their Bacterial Hosts

    Kalatzis, P. G., Mauritzen, Jesper Juel, Winther-Have, Caroline Sophie W, Michniewski, S., Millard, A., Tsertou, M. I., Katharios, P. & Middelboe, Mathias, 2023, In: International Journal of Molecular Sciences. 24, 4, 23 p., 3937.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Strain-specific quorum-sensing responses determine virulence properties in Vibrio anguillarum

    Mauritzen, Jesper Juel, Søndberg, E., Kalatzis, Panagiotis, Roager, L., Gram, L., Svenningsen, Sine Lo & Middelboe, Mathias, 2023, In: Environmental Microbiology. 25, 7, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2022
  6. Published

    In Vitro Evolution of Specific Phages Infecting the Fish Pathogen Flavobacterium psychrophilum

    Castillo, D., Højsting, A. R., Roosvall, A., Smyrlis, G., Jørgensen, J. & Middelboe, Mathias, 2022, In: PHAGE: Therapy, Applications, and Research. 3, 1, p. 28-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    On Single-Cell Enzyme Assays in Marine Microbial Ecology and Biogeochemistry

    Traving, Sachia Jo, Balmonte, J. P., Seale, D., Arnosti, C., Glud, R. N., Hallam, S. J. & Middelboe, Mathias, 2022, In: Frontiers in Marine Science. 9, 9 p., 846656.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Prevalence of genetically similar Flavobacterium columnare phages across aquaculture environments reveals a strong potential for pathogen control

    Runtuvuori-Salmela, A., Kunttu, H. M. T., Laanto, E., Almeida, G. M. F., Mäkelä, K., Middelboe, Mathias & Sundberg, L., 2022, In: Environmental Microbiology. 24, 5, p. 2404-2420 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Reversible mutations in gliding motility and virulence genes: A flexible and efficient phage defence mechanism in Flavobacterium psychrophilum

    Jørgensen, J., Sundell, K., Castillo, D., Dramshøj, L. S., Jørgensen, N. B., Madsen, S. B., Landor, L., Wiklund, T., Donati, V. L., Madsen, L., Dalsgaard, I. & Middelboe, Mathias, 2022, In: Environmental Microbiology. 24, 10, p. 4915-4930

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The Gut Microbiota of Healthy and Flavobacterium psychrophilum-Infected Rainbow Trout Fry Is Shaped by Antibiotics and Phage Therapies

    Donati, V. L., Madsen, L., Middelboe, Mathias, Strube, M. L. & Dalsgaard, I., 2022, In: Frontiers in Microbiology. 13, 21 p., 771296.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2021
  12. Published

    Bacteriophage Resistance Affects Flavobacterium columnare Virulence Partly via Mutations in Genes Related to Gliding Motility and the Type IX Secretion System

    Kunttu, H. M. T., Runtuvuori-Salmela, A., Sundell, K., Wiklund, T., Middelboe, Mathias, Landor, L., Ashrafi, R., Hoikkala, V. & Sundberg, L., 2021, In: Applied and Environmental Microbiology. 87, 16, 19 p., e00812-21 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Comparative Genomic Analyses of Flavobacterium psychrophilum Isolates Reveals New Putative Genetic Determinants of Virulence Traits

    Castillo, D., Donati, V. L., Jørgensen, J., Sundell, K., Dalsgaard, I., Madsen, L., Wiklund, T. & Middelboe, Mathias, 2021, In: Microorganisms. 9, 8, 15 p., 1658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Comparison of Delivery Methods in Phage Therapy against Flavobacterium columnare Infections in Rainbow Trout

    Kunttu, H. M. T., Runtuvuori-Salmela, A., Middelboe, Mathias, Clark, J. & Sundberg, L. R., 2021, In: Antibiotics. 10, 8, 19 p., 914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Dynamics of Baltic Sea phages driven by environmental changes

    Hoetzinger, M., Nilsson, E., Arabi, R., Osbeck, C. M. G., Pontiller, B., Hutinet, G., Bayfield, O. W., Traving, S., Kisand, V., Lundin, D., Pinhassi, J., Middelboe, Mathias & Holmfeldt, K., 2021, In: Environmental Microbiology. 23, 8, p. 4576-4594 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genome-informed approach to identify genetic determinants of Flavobacterium psychrophilum phage susceptibility

    Castillo, D., Jørgensen, J., Sundell, K., Madsen, L., Dalsgaard, I., Wiklund, T. & Middelboe, Mathias, 2021, In: Environmental Microbiology. 23, 8, p. 4185-4199 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Genomic Analysis of Pasteurella atlantica Provides Insight on Its Virulence Factors and Phylogeny and Highlights the Potential of Reverse Vaccinology in Aquaculture

    Ellul, R. M., Kalatzis, Panagiotis, Frantzen, C., Haugland, G. T., Gulla, S., Colquhoun, D. J., Middelboe, Mathias, Wergeland, H. I. & Rønneseth, A., 2021, In: Microorganisms. 9, 6, 22 p., 1215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Interactions between Rainbow Trout Eyed Eggs and Flavobacterium spp. Using a Bath Challenge Model: Preliminary Evaluation of Bacteriophages as Pathogen Control Agents

    Donati, V. L., Dalsgaard, I., Runtuvuori-Salmela, A., Kunttu, H., Jørgensen, J., Castillo, D., Sundberg, L., Middelboe, Mathias & Madsen, L., 2021, In: Microorganisms. 9, 5, 31 p., 971.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Interactions between the Prophage 919TP and Its Vibrio cholerae Host: Implications of gmd Mutation for Phage Resistance, Cell Auto-Aggregation, and Motility

    Li, N., Zeng, Y., Hu, B., Zhu, T., Svenningsen, Sine Lo, Middelboe, Mathias & Tan, D., 2021, In: Viruses. 13, 12, 15 p., 2342.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Phage-Mediated Control of Flavobacterium psychrophilum in Aquaculture: In vivo Experiments to Compare Delivery Methods

    Donati, V. L., Dalsgaard, I., Sundell, K., Castillo, D., Er-Rafik, M., Clark, J., Wiklund, T., Middelboe, Mathias & Madsen, L., 2021, In: Frontiers in Microbiology. 12, 16 p., 628309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Spatial variability of prokaryotic and viral abundances in the Kermadec and Atacama Trench regions

    Schauberger, C., Middelboe, Mathias, Larsen, M., Peoples, L. M., Bartlett, D. H., Kirpekar, F., Rowden, A. A., Wenzhöfer, F., Thamdrup, B. & Glud, R. N., 2021, In: Limnology and Oceanography. 66, 6, p. 2095-2109 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2020
  23. Published

    Bacteriophages: Emerging Applications in Medicine, Food, and Biotechnology

    Sohail, H. A., Coffey, A., Debrowska, K., Meyer, I. M., Middelboe, Mathias, Sohail, M. & Clokie, M. R. J., 2020, In: PHAGE: Therapy, Applications, and Research. 1, 2, p. 75-82 8 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  24. Published

    Bacteriophages as Biocontrol Agents for Flavobacterium psychrophilum Biofilms and Rainbow Trout Infections

    Sundell, K., Landor, L., Castillo, D., Middelboe, Mathias & Wiklund, T., 2020, In: PHAGE: Therapy, Applications, and Research. 1, 4, p. 198-204 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Beyond Cholera: Characterization of zot-Encoding Filamentous Phages in the Marine Fish Pathogen Vibrio anguillarum

    Mauritzen, Jesper Juel, Castillo, D., Tan, D., Svenningsen, Sine Lo & Middelboe, Mathias, 2020, In: Viruses. 12, 7, 17 p., 730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    High cell densities favor lysogeny: induction of an H20 prophage is repressed by quorum sensing and enhances biofilm formation in Vibrio anguillarum

    Tan, D., Hansen, Mads Frederik, de Carvalho, L. N., Røder, Henriette Lyng, Burmølle, Mette, Middelboe, Mathias & Svenningsen, Sine Lo, 2020, In: The ISME Journal. 14, 7, p. 1731-1742 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Sharp contrasts between freshwater and marine microbial enzymatic capabilities, community composition, and DOM pools in a NE Greenland fjord

    Balmonte, J. P., Hasler-Sheetal, H., Glud, R. N., Andersen, Thorbjørn Joest, Sejr, M. K., Middelboe, Mathias, Teske, A. & Arnosti, C., 2020, In: Limnology and Oceanography. 65, 1, p. 77-95 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2019
  29. Published

    P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions

    Henriksen, K., Rørbo, N., Rybtke, Morten Levin, Martinet, M. G., Tolker-Nielsen, Tim, Høiby, Niels, Middelboe, Mathias & Ciofu, Oana, 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms

    Hansen, Mads Frederik, Svenningsen, Sine Lo, Røder, Henriette Lyng, Middelboe, Mathias & Burmølle, Mette, 2019, In: Trends in Microbiology. 27, 9, p. 739-752 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

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