Conservative route to genome compaction in a miniature annelid

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Conservative route to genome compaction in a miniature annelid. / Martín-Durán, José M.; Vellutini, Bruno C.; Marlétaz, Ferdinand; Cetrangolo, Viviana; Cvetesic, Nevena; Thiel, Daniel; Henriet, Simon; Grau-Bové, Xavier; Carrillo-Baltodano, Allan M.; Gu, Wenjia; Kerbl, Alexandra; Marquez, Yamile; Bekkouche, Nicolas; Chourrout, Daniel; Gómez-Skarmeta, Jose Luis; Irimia, Manuel; Lenhard, Boris; Worsaae, Katrine; Hejnol, Andreas.

In: Nature Ecology and Evolution, Vol. 5, No. 2, 2021, p. 231-242.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Martín-Durán, JM, Vellutini, BC, Marlétaz, F, Cetrangolo, V, Cvetesic, N, Thiel, D, Henriet, S, Grau-Bové, X, Carrillo-Baltodano, AM, Gu, W, Kerbl, A, Marquez, Y, Bekkouche, N, Chourrout, D, Gómez-Skarmeta, JL, Irimia, M, Lenhard, B, Worsaae, K & Hejnol, A 2021, 'Conservative route to genome compaction in a miniature annelid', Nature Ecology and Evolution, vol. 5, no. 2, pp. 231-242. https://doi.org/10.1038/s41559-020-01327-6

APA

Martín-Durán, J. M., Vellutini, B. C., Marlétaz, F., Cetrangolo, V., Cvetesic, N., Thiel, D., Henriet, S., Grau-Bové, X., Carrillo-Baltodano, A. M., Gu, W., Kerbl, A., Marquez, Y., Bekkouche, N., Chourrout, D., Gómez-Skarmeta, J. L., Irimia, M., Lenhard, B., Worsaae, K., & Hejnol, A. (2021). Conservative route to genome compaction in a miniature annelid. Nature Ecology and Evolution, 5(2), 231-242. https://doi.org/10.1038/s41559-020-01327-6

Vancouver

Martín-Durán JM, Vellutini BC, Marlétaz F, Cetrangolo V, Cvetesic N, Thiel D et al. Conservative route to genome compaction in a miniature annelid. Nature Ecology and Evolution. 2021;5(2):231-242. https://doi.org/10.1038/s41559-020-01327-6

Author

Martín-Durán, José M. ; Vellutini, Bruno C. ; Marlétaz, Ferdinand ; Cetrangolo, Viviana ; Cvetesic, Nevena ; Thiel, Daniel ; Henriet, Simon ; Grau-Bové, Xavier ; Carrillo-Baltodano, Allan M. ; Gu, Wenjia ; Kerbl, Alexandra ; Marquez, Yamile ; Bekkouche, Nicolas ; Chourrout, Daniel ; Gómez-Skarmeta, Jose Luis ; Irimia, Manuel ; Lenhard, Boris ; Worsaae, Katrine ; Hejnol, Andreas. / Conservative route to genome compaction in a miniature annelid. In: Nature Ecology and Evolution. 2021 ; Vol. 5, No. 2. pp. 231-242.

Bibtex

@article{66874768fca549d9a962d735c53db4d1,
title = "Conservative route to genome compaction in a miniature annelid",
abstract = "The causes and consequences of genome reduction in animals are unclear because our understanding of this process mostly relies on lineages with often exceptionally high rates of evolution. Here, we decode the compact 73.8-megabase genome of Dimorphilus gyrociliatus, a meiobenthic segmented worm. The D. gyrociliatus genome retains traits classically associated with larger and slower-evolving genomes, such as an ordered, intact Hox cluster, a generally conserved developmental toolkit and traces of ancestral bilaterian linkage. Unlike some other animals with small genomes, the analysis of the D. gyrociliatus epigenome revealed canonical features of genome regulation, excluding the presence of operons and trans-splicing. Instead, the gene-dense D. gyrociliatus genome presents a divergent Myc pathway, a key physiological regulator of growth, proliferation and genome stability in animals. Altogether, our results uncover a conservative route to genome compaction in annelids, reminiscent of that observed in the vertebrate Takifugu rubripes.",
author = "Mart{\'i}n-Dur{\'a}n, {Jos{\'e} M.} and Vellutini, {Bruno C.} and Ferdinand Marl{\'e}taz and Viviana Cetrangolo and Nevena Cvetesic and Daniel Thiel and Simon Henriet and Xavier Grau-Bov{\'e} and Carrillo-Baltodano, {Allan M.} and Wenjia Gu and Alexandra Kerbl and Yamile Marquez and Nicolas Bekkouche and Daniel Chourrout and G{\'o}mez-Skarmeta, {Jose Luis} and Manuel Irimia and Boris Lenhard and Katrine Worsaae and Andreas Hejnol",
note = "Publisher Correction: Conservative route to genome compaction in a miniature annelid DOI: 10.1038/s41559-020-01366-z",
year = "2021",
doi = "10.1038/s41559-020-01327-6",
language = "English",
volume = "5",
pages = "231--242",
journal = "Nature Ecology & Evolution",
issn = "2397-334X",
publisher = "nature publishing group",
number = "2",

}

RIS

TY - JOUR

T1 - Conservative route to genome compaction in a miniature annelid

AU - Martín-Durán, José M.

AU - Vellutini, Bruno C.

AU - Marlétaz, Ferdinand

AU - Cetrangolo, Viviana

AU - Cvetesic, Nevena

AU - Thiel, Daniel

AU - Henriet, Simon

AU - Grau-Bové, Xavier

AU - Carrillo-Baltodano, Allan M.

AU - Gu, Wenjia

AU - Kerbl, Alexandra

AU - Marquez, Yamile

AU - Bekkouche, Nicolas

AU - Chourrout, Daniel

AU - Gómez-Skarmeta, Jose Luis

AU - Irimia, Manuel

AU - Lenhard, Boris

AU - Worsaae, Katrine

AU - Hejnol, Andreas

N1 - Publisher Correction: Conservative route to genome compaction in a miniature annelid DOI: 10.1038/s41559-020-01366-z

PY - 2021

Y1 - 2021

N2 - The causes and consequences of genome reduction in animals are unclear because our understanding of this process mostly relies on lineages with often exceptionally high rates of evolution. Here, we decode the compact 73.8-megabase genome of Dimorphilus gyrociliatus, a meiobenthic segmented worm. The D. gyrociliatus genome retains traits classically associated with larger and slower-evolving genomes, such as an ordered, intact Hox cluster, a generally conserved developmental toolkit and traces of ancestral bilaterian linkage. Unlike some other animals with small genomes, the analysis of the D. gyrociliatus epigenome revealed canonical features of genome regulation, excluding the presence of operons and trans-splicing. Instead, the gene-dense D. gyrociliatus genome presents a divergent Myc pathway, a key physiological regulator of growth, proliferation and genome stability in animals. Altogether, our results uncover a conservative route to genome compaction in annelids, reminiscent of that observed in the vertebrate Takifugu rubripes.

AB - The causes and consequences of genome reduction in animals are unclear because our understanding of this process mostly relies on lineages with often exceptionally high rates of evolution. Here, we decode the compact 73.8-megabase genome of Dimorphilus gyrociliatus, a meiobenthic segmented worm. The D. gyrociliatus genome retains traits classically associated with larger and slower-evolving genomes, such as an ordered, intact Hox cluster, a generally conserved developmental toolkit and traces of ancestral bilaterian linkage. Unlike some other animals with small genomes, the analysis of the D. gyrociliatus epigenome revealed canonical features of genome regulation, excluding the presence of operons and trans-splicing. Instead, the gene-dense D. gyrociliatus genome presents a divergent Myc pathway, a key physiological regulator of growth, proliferation and genome stability in animals. Altogether, our results uncover a conservative route to genome compaction in annelids, reminiscent of that observed in the vertebrate Takifugu rubripes.

UR - https://doi.org/10.1038/s41559-020-01366-z

U2 - 10.1038/s41559-020-01327-6

DO - 10.1038/s41559-020-01327-6

M3 - Journal article

C2 - 33199869

AN - SCOPUS:85096051868

VL - 5

SP - 231

EP - 242

JO - Nature Ecology & Evolution

JF - Nature Ecology & Evolution

SN - 2397-334X

IS - 2

ER -

ID: 252679447