Per Amstrup Pedersen

Per Amstrup Pedersen

Associate Professor


  1. 2024
  2. Published

    Imaging of extracellular and intracellular ATP in pancreatic beta cells reveals correlation between glucose metabolism and purinergic signalling

    Ghiasi, S. M., Christensen, Nynne, Pedersen, Per Amstrup, Skovhøj, Emil Zeng & Novak, Ivana, 2024, In: Cellular Signalling. 117, 12 p., 111109.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2023
  4. Published

    pXOOY: A dual-function vector for expression of membrane proteins in Saccharomyces cerevisiae and Xenopus laevis oocytes

    Vold, Victoria Amstrup, Glanville, S., Klærke, Dan Arne & Pedersen, Per Amstrup, 2023, In: PLoS ONE. 18, 2, 16 p., e0281868.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2022
  6. Published

    Isolation and Crystallization of the D156C Form of Optogenetic ChR2

    Zhang, L., Wang, Kaituo, Ning, S., Pedersen, Per Amstrup, Duelli, A. S. & Gourdon, Pontus Emanuel, 2022, In: Cells. 11, 5, 11 p., 895.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

    Merklinger, L., Bauer, J., Pedersen, Per Amstrup, Damgaard, R. B. & Morth, J. P., 2022, In: Life Science Alliance. 5, 8, 13 p., e202101309.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Production of an Active, Human Membrane Protein in Saccharomyces cerevisiae: Full-Length FICD

    Virolainen, M. S., Søltoft, C. L., Pedersen, Per Amstrup & Ellgaard, Lars, 2022, In: International Journal of Molecular Sciences. 23, 5, 17 p., 2458.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    The role of water coordination in the pH-dependent gating of hAQP10

    Truelsen, S. F., Missel, Julie Winkel, Gotfryd, K., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel, Lindorff-Larsen, Kresten & Hélix-Nielsen, C., 2022, In: B B A - Biomembranes. 1864, 1, 13 p., 183809.

    Research output: Contribution to journalJournal articlepeer-review

  10. 2021
  11. Published

    Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

    Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations

    Pimpão, C., Wragg, D., Bonsignore, R., Aikman, B., Pedersen, Per Amstrup, Leoni, S., Soveral, G. & Casini, A., 2021, In: Metallomics. 13, 9, 11 p., mfab053.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Occipital Horn Syndrome as a Result of Splice Site Mutations in ATP7A. No Activity of ATP7A Splice Variants Missing Exon 10 or Exon 15

    Møller, L. B., Mogensen, M., Weaver, D. D. & Pedersen, Per Amstrup, 2021, In: Frontiers in Molecular Neuroscience. 14, 12 p., 532291.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Order and disorder - An integrative structure of the full-length human growth hormone receptor

    Kassem, N., Araya-Secchi, R., Bugge, K., Barclay, A., Steinocher, H., Khondker, A., Wang, Yong, Lenard, A. J., Bürck, J., Sahin, Cagla, Ulrich, A. S., Landreh, M., Pedersen, M. C., Rheinstädter, M. C., Pedersen, Per Amstrup, Lindorff-Larsen, Kresten, Arleth, Lise & Kragelund, Birthe Brandt, 2021, In: Science Advances. 7, 27, 20 p., eabh3805.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Overproduction of Human Zip (SLC39) Zinc Transporters in Saccharomyces cerevisiae for Biophysical Characterization

    Becares, E. R., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2021, In: Cells. 10, 2, 21 p., 213.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Recombinant production of membrane proteins in yeast

    Preisler, Sarah Spruce, Hansen, K. M., Nurup, C. N., Beich-Frandsen, M. & Pedersen, Per Amstrup, 2021, Methods in Enzymology. Pyle, A. M. & Christianson, D. W. (eds.). Academic Press, Vol. 660. p. 21-52 32 p. (Methods in Enzymology, Vol. 660).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. 2020
  18. Published

    Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

    Molbaek, K., Tejada, M., Ricke, C. H., Scharff-Poulsen, P., Ellekvist, P., Helix-Nielsen, C., Kumar, N., Klærke, Dan Arne & Pedersen, Per Amstrup, 2020, In: Microbial Cell Factories. 19, 1, 183.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    The rapid “teabag” method for high-end purification of membrane proteins

    Hering, J., Missel, Julie Winkel, Zhang, L., Gunnarsson, A., Castaldo, M., Pedersen, Per Amstrup, Ek, M., Gourdon, Pontus Emanuel & Snijder, H. J., 2020, In: Scientific Reports. 10, 11 p., 16167.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Yeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies

    Kassem, N., Kassem, M. M., Pedersen, Stine Helene Falsig, Pedersen, Per Amstrup & Kragelund, Birthe Brandt, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 14 p., 183272.

    Research output: Contribution to journalJournal articlepeer-review

  21. 2019
  22. Published

    Characterization of Hailey-Hailey Disease-mutants in presence and absence of wild type SPCA1 using Saccharomyces cerevisiae as model organism

    Muncanovic, D., Justesen, M. H., Preisler, Sarah Spruce & Pedersen, Per Amstrup, 2019, In: Scientific Reports. 9, 25 p., 12442.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Human aquaporin-5 facilitates hydrogen peroxide permeation affecting adaption to oxidative stress and cancer cell migration

    Rodrigues, C., Pimpão, C., Mósca, A. F., Coxixo, A. S., Lopes, D., Da Silva, I. V., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2019, In: Cancers. 11, 7, 17 p., 932.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journalJournal articlepeer-review

  26. 2018
  27. Published

    From channel proteins to industrial biomimetic membrane technology

    Pedersen, Per Amstrup, Bjørkskov, F. B., Alvisse, S. & Hélix-Nielsen, C., 2018, In: Faraday Discussions. 209, p. 287-301 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Human AQP5 facilitates hydrogen peroxide permeation and improves cell resistance to oxidative stress

    Rodrigues, C., Mósca, A. F., Lopes, D., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2018, In: Free Radical Biology and Medicine. 120, Suppl. 1, p. S70 P-86.

    Research output: Contribution to journalConference abstract in journalpeer-review

  29. Published

    Human adipose glycerol flux is regulated by a pH gate in AQP10

    Gotfryd, K., Mósca, A. F., Missel, Julie Winkel, Truelsen, S. F., Wang, Kaituo, Spulber, M., Krabbe, S., Hélix-nielsen, C., Laforenza, U., Soveral, G., Pedersen, Per Amstrup & Gourdon, Pontus Emanuel, 2018, In: Nature Communications. 9, p. 1-11 4749.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

    Klærke, Dan Arne, Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, Per Amstrup & Callø, Kirstine, 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.

    Research output: Contribution to journalJournal articlepeer-review

  31. 2017
  32. Published

    Purification and functional comparison of nine human Aquaporins produced in Saccharomyces cerevisiae for the purpose of biophysical characterization

    Bjørkskov, F. B., Krabbe, S., Nurup, C. N., Missel, Julie Winkel, Spulber, M., Bomholt, J., Molbaek, K., Helix-Nielsen, C., Gotfryd, K., Gourdon, Pontus Emanuel & Pedersen, Per Amstrup, 4 Dec 2017, In: Scientific Reports. 7, 21 p., 16899.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

    Skjørringe, T., Pedersen, Per Amstrup, Thorborg, S. S., Nissen, P., Gourdon, Pontus Emanuel & Møller, L. B., 7 Apr 2017, In: Scientific Reports. 7, 18 p., 757.

    Research output: Contribution to journalJournal articlepeer-review

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