Genevieve Thon

Genevieve Thon

Associate Professor


  1. 2023
  2. Published

    Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching

    Maki, T., Thon, Genevieve & Iwasaki, H., 2023, In: Nucleic acids symposium series. 51, 8, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2022
  4. Published

    Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast Schizosaccharomyces pombe

    Esquivel-Chávez, A., Maki, T., Tsubouchi, H., Handa, T., Kimura, H., Haber, J. E., Thon, Genevieve & Iwasaki, H., 2022, In: Genes and Genetic Systems. 97, 3, p. 123-138 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The transcription factor Atf1 lowers the transition barrier for nucleosome-mediated establishment of heterochromatin

    Nickels, Jan Fabio, Della-Rosa, M. E., Miguelez Goyeneche, I., Charlton, Sebastian Jespersen, Sneppen, Kim & Thon, Genevieve, 2022, In: Cell Reports. 39, 7, 17 p., 110828.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2021
  7. Published

    Establishment of heterochromatin in domain-size-dependent bursts

    Nickels, Jan Fabio, Edwards, A. K., Charlton, Sebastian Jespersen, Mortensen, A. M., Hougaard, S. C. L., Trusina, Ala, Sneppen, Kim & Thon, Genevieve, 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2020
  9. Published

    Integrity of a heterochromatic domain ensured by its boundary elements

    Charlton, Sebastian Jespersen, Jørgensen, M. M. & Thon, Genevieve, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 35, p. 21504-21511 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Mating-type switching by homology-directed recombinational repair: a matter of choice

    Thon, Genevieve, Maki, T., Haber, J. E. & Iwasaki, H., 2019, In: Current Genetics. 65, 2, p. 351-362

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2018
  13. Published

    New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe

    Maki, T., Ogura, N., Haber, J. E., Iwasaki, H. & Thon, Genevieve, May 2018, In: PLOS Genetics. 14, 5, p. 1-25 e1007424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Dependency of Heterochromatin Domains on Replication Factors

    Jahn, L. J., Mason, B., Brøgger, Peter, Toteva, T., Nielsen, D. K. & Thon, Genevieve, 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 2, p. 477-489 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structure of the replication regulator Sap1 reveals functionally important interfaces

    Jørgensen, M. L. M., Ekundayo, B., Zaratiegui, M., Skriver, Karen, Thon, Genevieve & Schalch, T., 2018, In: Scientific Reports. 8, 9 p., 10930.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2017
  17. Published

    Ethyl methanesulfonate mutagenesis in Schizosaccharomyces pombe

    Ekwall, K. & Thon, Genevieve, Aug 2017, In: Cold Spring Harbor Protocols. 2017, 8, p. 643-646 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genetic analysis of Schizosaccharomyces pombe

    Ekwall, K. & Thon, Genevieve, Aug 2017, In: Cold Spring Harbor Protocols. 2017, 8, p. 593-605 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Mating-type determination in Schizosaccharomyces pombe

    Ekwall, K. & Thon, Genevieve, Aug 2017, In: Cold Spring Harbor Protocols. 2017, 8, p. 641-642 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Selecting Schizosaccharomyces pombe diploids

    Ekwall, K. & Thon, Genevieve, Jul 2017, In: Cold Spring Harbor Protocols. 2017, 7, p. 537-540 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Setting up Schizosaccharomyces pombe crosses/matings

    Ekwall, K. & Thon, Genevieve, Jul 2017, In: Cold Spring Harbor Protocols. 2017, 7, p. 533-536 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Spore analysis and tetrad dissection of Schizosaccharomyces pombe

    Ekwall, K. & Thon, Genevieve, Jul 2017, In: Cold Spring Harbor Protocols. 2017, 7, p. 541-544 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast

    Toteva, T., Mason, B., Kanoh, Y., Brøgger, P., Green, D., Hansen, J. V., Masai, H. & Thon, Genevieve, 31 Jan 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 1093-1098 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2016
  25. Published

    Nucleation and spreading of a heterochromatic domain in fission yeast

    Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2015
  27. Published

    Targeting of SUMO substrates to a Cdc48-Ufd1-Npl4 segregase and STUbL pathway in fission yeast

    Køhler, J. B., Tammsalu, T., Jørgensen, M. L. M., Steen, N., Hay, R. T. & Thon, Genevieve, 2015, In: Nature Communications. 6, 14 p., 8827.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2013
  29. Published

    Concerted action of the Ubiquitin-Fusion Degradation Protein 1 (Ufd1) and Sumo-Targeted Ubiquitin Ligases (STUbLs) in the DNA-damage response

    Køhler, J. B., Jørgensen, M. L. M., Beinoraite, G., Thorsen, M. & Thon, Genevieve, 2013, In: P L o S One. 8, 11, 15 p., e80442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Subnuclear relocalization and silencing of a chromosomal region by an ectopic ribosomal DNA repeat

    Jakociunas, T., Domange Jordö, M. E., Mebarek, M. A., Bünner, C. M., Hansen, J. V., Oddershede, L. B. & Thon, Genevieve, 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 47, p. E4465-E4473 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Two portable recombination enhancers direct donor choice in fission yeast heterochromatin

    Jakociunas, T., Holm, L. R., Hansen, J. V., Trusina, Ala & Thon, Genevieve, 2013, In: P L o S Genetics. 9, 10, 14 p., e1003762.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2012
  33. Published

    Mediator regulates non-coding RNA transcription at fission yeast centromeres

    Thorsen, M., Hansen, H., Venturi, M., Holmberg, Steen & Thon, Genevieve, 2012, In: Epigenetics & Chromatin. 5, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    New romance between RNA degradation pathways: Mmi1 and RNAi meet on heterochromatic islands

    Holm, L. R. & Thon, Genevieve, 2012, In: E M B O Journal. 31, p. 2242 - 2243 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2011
  36. Published

    H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases

    Hansen, K. R., Hazan, I., Shanker, S., Watt, S., Hansen, J. V., Bähler, J., Martienssen, R. A., Partridge, J. F., Cohen, A. & Thon, Genevieve, 2011, In: P L o S Genetics. 7, 1, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2010
  38. Published

    RNAi and heterochromatin repress centromeric meiotic recombination

    Ellermeier, C., Higuchi, E. C., Phadnis, N., Holm, L., Geelhood, J. L., Thon, Genevieve & Smith, G. R., 11 May 2010, In: Proceedings of the National Academy of Sciences USA (PNAS). 107, 19, p. 8701-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2008
  40. Published

    Competing to destroy: a fight between two RNA-degradation systems

    Thon, Genevieve, 2008, In: Nature Structural and Molecular Biology. 15, 10, p. 1001-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Histone modifications: Cycling with chromosomal replication

    Thon, Genevieve, 2008, In: Current Biology. 18, 9, p. 380-382 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2007
  43. Published

    Theoretical analysis of epigenetic cell memory by nucleosome modification

    Dodd, I. B., Micheelsen, M. A., Sneppen, Kim & Thon, Genevieve, 2007, In: Cell. 129, 4, p. 813-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2006
  45. Published

    Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1

    Hansen, K. R., Ibarra, P. T. & Thon, Genevieve, 2006, In: Nucleic Acids Research. 34, 1, p. 78-88

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2005
  47. Published

    Global Effects on Gene Expression in Fission Yeast by Silencing and RNA Interference Machineries

    Hansen, K. R., Burns, G., Mata, J., Volpe, T. A., Martienssen, R. A., Bähler, J. & Thon, Genevieve, 2005, In: Molecular and Cellular Biology. 25, 2, p. 590-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The Clr7 and Clr8 Directionality Factors and the Pcu4 Cullin Mediate Heterochromatin Formation in the Fission Yeast Schizosaccharomyces pombe

    Thon, Genevieve, Hansen, K. R., Altes, S. P., Sidhu, D., Singh, G., Verhein-Hansen, J., Bonaduce, M. J. & Klar, A. J. S., 2005, In: Genetics. 171, 4, p. 1583-1595

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2004
  50. Published

    A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe

    Bjerling, P., Ekwall, K., Egel, Richard & Thon, Genevieve, 2004, In: Nucleic Acids Research. 32, 15, p. 4421-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Anomalous Diffusion in Living Yeast Cells

    Tolic-Norrelykke, I. M., Munteanu, E. L., Thon, Genevieve, Oddershede, L. B. & Berg-Sorensen, K., 2004, In: Physical Review Letters. Vol. 93 No. 7, August 13th, p. Artikel No. 078102

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Positioning and elongation of the fission yeast spindle by microtubule-based pushing

    Tolic-Norrelykke, I. M., Sacconi, L., Thon, Genevieve & Pavone, F. S., 2004, In: Current Biology. Vol. 14. No. 13., p. 1181-1186

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance

    Xhemalce, B., Seeler, J. S., Thon, Genevieve, Dejean, A. & Arcangioli, B., 2004, In: EMBO Journal. Vol. 23 No. 19, p. 3844-3853

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2003
  55. Published

    Mating-type cassettes: structure, switching and silencing

    Arcangioli, B. & Thon, Genevieve, 2003, The Molecular Biology of Schizosaccharomyces pombe.. Springer, p. 129-148

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  56. 2002
  57. Published

    The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region

    Nielsen, I. S., Nielsen, Olaf, Murray, J. M. & Thon, Genevieve, 1 Aug 2002, In: Eukaryotic Cell (Online Edition). 1, 4, p. 613-25 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Expression-state boundaries in the mating-type region of fission yeast

    Thon, Genevieve, Bjerling, K. P., Bünner, C. M. & Hansen, J. V., 2002, In: Genetics. 161, p. 611-622

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity

    Bjerling, P., Silverstein, R., Thon, Genevieve, Caudy, A., Grewal, S. & Ekwall, K., 2002, In: Mol. Cell. Biol.. 22, p. 2170-2181

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. 2000
  61. Published

    Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal locations

    Thon, Genevieve & Hansen, J. V., 2000, In: Genetics. 155, p. 551-568

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. 1999
  63. Published

    Localization and properties of a silencing element near the mat3-M mating-type cassette of Schizosaccharomyces pombe

    Thon, Genevieve, Bjerling, P. & Nielsen, I. S., 1999, In: Genetics. 151, p. 945-963

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 1997
  65. Published

    Epigenetic inheritance of transcriptional silencing and switching competence in fission yeast

    Thon, Genevieve & Friis, T., 1997, In: Genetics. 145, p. 685-696

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. 1994
  67. Published

    Three additional linkage groups that repress transcription and meiotic recombination in the mating-type region of Schizosaccharomyces pombe

    Thon, Genevieve, Cohen, A. & Klar, A., 1994, In: Genetics. 138, 1, p. 29-38 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. 1993
  69. Published

    Directionality of fission yeast mating-type interconversion is controlled by the location of the donor loci

    Thon, Genevieve, 1993, In: Genetics. 134, 4, p. 1045-1054 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. 1992
  71. Published

    The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast

    Thon, Genevieve & Klar, A., 1992, In: Genetics. 131, 2, p. 287-296 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 1990
  73. Published

    Trypanosome variable surface glycoproteins: composite genes and order of expression

    Thon, Genevieve, Baltz, T., Giroud, C. & Eisen, H., 1990, In: Genes & Development. 4, 8, p. 1374-1383 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. 1989
  75. Published

    Antigenic diversity by the recombination of pseudogenes

    Thon, Genevieve, Baltz, T. & Eisen, H., 1989, In: Genes & Development. 3, 8, p. 1247-1254 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Genetic selection and DNA sequences of 4.5S RNA homologs

    Brown, Stanley, Thon, Genevieve & Tolentino, E., 1989, In: Journal of Bacteriology. 171, 12, p. 6517-20 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13944