Jacob B. Hansen

Jacob B. Hansen

Associate Professor

Member of:

    ORCID: 0000-0001-5249-2586

    Publication year:
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    1 - 25 out of 55Page size: 25
    1. 2024
    2. Published

      Editorial overview: New and revitalized old targets in metabolic disease

      Hansen, Jacob B. & Novak, Ivana, 2024, In: Current Opinion in Pharmacology. 75, 3 p., 102434.

      Research output: Contribution to journal › Editorial › Research › peer-review

    3. 2023
    4. Published

      Full activation of thermogenesis in brown adipocytes requires Basigin action

      Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      The ABA/LANCL1/2 Hormone/Receptor System Controls Adipocyte Browning and Energy Expenditure

      Spinelli, S., Cossu, V., Passalacqua, M., Hansen, Jacob B., Guida, L., Magnone, M., Sambuceti, G., Marini, C., Sturla, L. & Zocchi, E., 2023, In: International Journal of Molecular Sciences. 24, 4, 27 p., 3489.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2022
    7. Published

      An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs

      Alvarez-Dominguez, J. R., Winther, Sally, Hansen, Jacob B., Lodish, H. F. & Knoll, M., 2022, In: iScience. 25, 1, 25 p., 103680.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Lipolysis regulates major transcriptional programs in brown adipocytes

      Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2021
    10. Published

      3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis

      Shen, J. X., Couchet, M., Dufau, J., de Castro Barbosa, T., Ulbrich, M. H., Helmstädter, M., Kemas, A. M., Zandi Shafagh, R., Marques, M., Hansen, Jacob B., Mejhert, N., Langin, D., Rydén, M. & Lauschke, V. M., 2021, In: Advanced Science. 8, 16, 17 p., 2100106.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

      Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Parathyroid hormone receptor stimulation induces human adipocyte lipolysis and browning

      Breining, P., Pedersen, S. B., Kjolby, M., Hansen, Jacob B., Jessen, N. & Richelsen, B., 2021, In: European Journal of Endocrinology. 184, 5, p. 687-697 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. 2020
    14. Published

      Beta-1 and Not Beta-3 Adrenergic Receptors May Be the Primary Regulator of Human Brown Adipocyte Metabolism

      Riis-Vestergaard, M. J., Richelsen, B., Bruun, J. M., Li, W., Hansen, Jacob B. & Pedersen, S. B., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, 12 p., dgz298.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration

      Tozzi, M., Hansen, Jacob B. & Novak, Ivana, 2020, In: Acta Physiologica. 228, 2, 18 p., e13360.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes

      Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      The autocrine role of FGF21 in cultured adipocytes

      Justesen, S., Haugegaard, K. V., Hansen, Jacob B., Hansen, Harald S. & Andersen, B., 2020, In: The Biochemical journal. 477, 13, p. 2477-2487 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. 2019
    19. Published

      Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice

      Danneskiold-Samsøe, Niels Banhos, Sonne, Si Brask, Larsen, J. M., Hansen, Ann Normann, Fjære, E., Isidor, Marie Sophie, Petersen, S., Henningsen, J., Severi, I., Sartini, L., Schobers, Y., Wolf, J., Nockhers, W. A., Wolfrum, C., Cinti, S., Sina, C., Hansen, Jacob B., Madsen, L., Brix, S. & Kristiansen, Karsten, 2019, In: Scientific Reports. 9, 13 p., 8979.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Possible link between FSH and RANKL release from adipocytes in men with impaired gonadal function including Klinefelter syndrome

      Mortensen, L. J., Lorenzen, M., Jørgensen, N., Andersson, A., Nielsen, J. E., Petersen, L. I., Lanske, B., Juul, Anders, Hansen, Jacob B. & Jensen, M. B., 2019, In: Bone. 123, p. 103-114

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. 2018
    22. Published

      GSK3 is a negative regulator of the thermogenic program in brown adipocytes

      Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro

      Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, Jacob B., Pedersen, S. B., Richelsen, B. & Jessen, N., 2018, In: Diabetes, Obesity and Metabolism. 20, 9, p. 2264-2273

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

      Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2017
    26. Published

      SYK kinase mediates brown fat differentiation and activation

      Knoll, M., Winther, Sally, Natarajan, A., Yang, H., Jiang, M., Thiru, P., Shahsafaei, A., Chavarria, T. E., Lamming, D. W., Sun, L., Hansen, Jacob B. & Lodish, H. F., 13 Dec 2017, In: Nature Communications. 8, 11 p., 2115.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism

      Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, Marie Sophie, Markussen, L. K., Viuff, B. M., Lambert, Ian Henry, Hansen, Jacob B. & Pedersen, Stine Helene Falsig, 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor

      Markussen, L. K., Isidor, Marie Sophie, Breining, P., Andersen, E. S., Rasmussen, N. E., Petersen, L. I., Pedersen, S. B., Richelsen, B. & Hansen, Jacob B., 28 Sep 2017, In: PLoS ONE. 12, 9, 17 p., e0185624.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Regulation of glycolysis in brown adipocytes by HIF-1α

      Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. 2016
    31. Published

      An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes

      Isidor, Marie Sophie, Winther, Sally, Basse, A. L., Petersen, M. C. H., Cannon, B., Nedergaard, J. & Hansen, Jacob B., 2016, In: Adipocyte. 5, 2, p. 175-185 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      The protein source determines the potential of high protein diets to attenuate obesity development in C57BL/6J mice

      Aune, U. L., Myrmel, L. S., Fjære, E., Rønnevik, A. K., Bjelland, S., Fauske, K. R., Holm, J. B., Basse, A. L., Hansen, Jacob B., Liaset, B., Kristiansen, Karsten & Madsen, L., 2016, In: Adipocytes. 5, 2, p. 196-211 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α

      Hallenborg, P., Fjære, E., Liaset, B., Petersen, R. K., Murano, I., Sonne, Si Brask, Falkerslev, M., Winther, Sally, Jensen, Benjamin Anderschou Holbech, Ma, Tao, Hansen, Jacob B., Cinti, S., Blagoev, B., Madsen, L. & Kristiansen, Karsten, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 2, p. E116-128 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. 2015
    35. Published

      Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

      Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 8300