Janine Zara Bowring

Janine Zara Bowring

Assistant Professor

Understanding bacteria and the viruses that infect them

My research interests lie in understanding the interactions between bacteria and their bacteriophages - viruses that only infect bacteria. These 'phages' can either kill their bacterial hosts or change them by facilitating horizontal transfer of genes to nearby bacteria. Some recent projects have focused on new routes of horizontal gene transfer by staphylococcal phages (phages that only infect staphylococci) and how lytic phages can overcome anti-phage defense systems like CRISPR-Cas in S. aureus

Selected publications

  1. Published

    An Endogenous Staphylococcus aureus CRISPR-Cas System Limits Phage Proliferation and Is Efficiently Excised from the Genome as Part of the SCCmec Cassette

    Mikkelsen, K., Bowring, Janine Zara, Ng, Y. K., Svanberg Frisinger, Frida, Maglegaard, J. K., Li, Q., Sieber, R. N., Petersen, A., Andersen, P. S., Rostøl, J. T., Høyland-Kroghsbo, Nina Molin & Ingmer, Hanne, 2023, In: Microbiology Spectrum. 11, 4, e01277-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus

    Yang, Jingxian, Bowring, Janine Zara, Krusche, J., Lehmann, Esther, Bejder, Benjamin Svejdal, Fulaz Silva, Stephanie, Bojer, Martin Saxtorph, Grunert, T., Peschel, A. & Ingmer, Hanne, 2023, In: Cell Reports. 42, 9, 113154.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Screening for Highly Transduced Genes in Staphylococcus aureus Revealed Both Lateral and Specialized Transduction

    Bowring, Janine Zara, Su, Y., Alsaadi, Ahlam Musaibeh M, Svenningsen, Sine Lo, Parkhill, J. & Ingmer, Hanne, 2022, In: Microbiology Spectrum. 10, 1, e02423-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature

    Ciges Tomas, Jose Rafael, Alite, C., Humphrey, S., Donderis, J., Bowring, Janine Zara, Salvatella, X., Penadés, J. R. & Marina, A., 2019, In: Nature Communications. 10, 1, p. 3676

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pirating conserved phage mechanisms promotes promiscuous staphylococcal pathogenicity island transfer

    Bowring, Janine Zara, Neamah, M. M., Donderis, J., Mir-Sanchis, I., Alite, C., Ciges Tomas, Jose Rafael, Maiques, E., Medmedov, I., Marina, A. & Penadés, J. R., 8 Aug 2017, In: eLife. 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization

    Donderis, J., Bowring, Janine Zara, Maiques, E., Ciges Tomas, Jose Rafael, Alite, C., Mehmedov, I., Tormo-Mas, M. A., Penadés, J. R. & Marina, A., Sep 2017, In: PLoS Pathogens. 13, 9, p. e1006581

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 198861542