Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor


  1. 2024
  2. E-pub ahead of print

    Acid–base transporters in the context of tumor heterogeneity

    Pedersen, Stine Helene Falsig, 2024, (E-pub ahead of print) In: Pflugers Archiv European Journal of Physiology.

    Research output: Contribution to journalReviewpeer-review

  3. Published

    Transmembrane transporter proteins: Capturing transport in motion

    Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.

    Research output: Contribution to journalEditorialpeer-review

  4. 2023
  5. Published

    Aquaporin water channels affect the response of conventional anticancer therapies of 3D grown breast cancer cells

    Edamana, S., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2023, In: Biochemical and Biophysical Research Communications. 639, p. 126-133 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Chronic acidosis rewires cancer cell metabolism through PPARα signaling

    Rolver, M. G., Holland, L. K. K., Ponniah, M., Prasad, N. S., Yao, Jiayi, Schnipper, J., Kramer, S., Elingaard-Larsen, L., Pedraz-Cuesta, E., Liu, B., Pardo, L. A., Maeda, K., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 8, 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness

    Czaplinska, D., Ialchina, Renata, Andersen, Henriette Berg, Yao, Jiayi, Stigliani, Arnaud, Dannesboe, Johs, Flinck, M., Chen, X., Mitrega, J., Gnosa, S. P., Dmytriyeva, O., Alves, F., Napp, J., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 6, p. 1210-1225 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia

    Severin, M., Pedersen, E. L., Borre, M. T., Axholm, I., Christiansen, F. B., Ponniah, M., Czaplinska, D., Larsen, T., Pardo, L. A. & Pedersen, Stine Helene Falsig, 2023, In: Journal of Cell Science. 136, 7, 20 p., jcs260687.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison

    Panou, D. A., Pedersen, Stine Helene Falsig, Kristensen, Mie & Nielsen, Hanne Mørck, 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    How protons pave the way to aggressive cancers

    Swietach, P., Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2023, In: Nature Reviews Cancer. 23, p. 825-841 17 p.

    Research output: Contribution to journalReviewpeer-review

  11. Published

    Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4

    Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Goncalves-Alves, E., Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

    Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2022
  14. Published

    Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca2+ Entry and Interaction with PI3K/CaM

    Schnipper, J., Kouba, S., Hague, F., Girault, A., Telliez, M., Guenin, S., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: Cancers. 14, 19, 27 p., 4946.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression

    Elingaard-Larsen, L. O., Rolver, M. G., Sørensen, E. E. & Pedersen, Stine Helene Falsig, 2022, From Malignant Transformation to Metastasis: Ion Transport in Tumor Biology. Stock, C. & Pardo, L. A. (eds.). Springer, p. 1-38 38 p. (Reviews of Physiology, Biochemistry and Pharmacology, Vol. 182).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase

    Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.

    Research output: Contribution to journalConference abstract in journalpeer-review

  17. Published

    The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca2+-Independent Manner

    Schnipper, J., Kouba, S., Hague, F., Girault, A., Rybarczyk, P., Telliez, M., Guenin, S., Tebbakha, R., Sevestre, H., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: International Journal of Molecular Sciences . 23, 14, 20 p., 7923.

    Research output: Contribution to journalJournal articlepeer-review

  18. 2021
  19. Published
  20. Published

    Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets

    Andersen, Henriette Berg, Ialchina, Renata, Pedersen, Stine Helene Falsig & Czaplinska, D., 2021, In: Cancer and Metastasis Reviews. 40, 4, p. 1093-1114 22 p.

    Research output: Contribution to journalReviewpeer-review

  21. Published

    Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer

    Rolver, M. G. & Pedersen, Stine Helene Falsig, 2021, In: British Journal of Cancer. 124, p. 1-2 2 p.

    Research output: Contribution to journalEditorialpeer-review

  22. Published

    The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer

    Pedersen, Stine Helene Falsig, Flinck, M. & Pardo, L. A., 2021, In: International Journal of Molecular Sciences. 22, 10, 27 p., 5209.

    Research output: Contribution to journalReviewpeer-review

  23. Published

    The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells

    Doray, A., Lemoine, R., Severin, M., Chadet, S., Lopez-Charcas, O., Héraud, A., Baron, C., Besson, P., Monteil, A., Pedersen, Stine Helene Falsig & Roger, S., 2021, In: Cells. 10, 7, 15 p., 1624.

    Research output: Contribution to journalJournal articlepeer-review

  24. 2020
  25. Published

    The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

    Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4

    Thiesen, L., Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Helene Falsig, Crocoll, C., Nour-Eldin, Hussam Hassan & Wellendorph, Petrine, 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, p. 1-9 105203.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion

    Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

    Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

    Bagdonaite, Ieva , Pallesen, E. M. H., Ye, Z., Vakhrushev, Sergey, Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Kramer, S. H., Pedersen, Stine Helene Falsig, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2020, In: EMBO Reports. 21, 6, 17 p., e48885.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1

    Rolver, M. G., Elingaard-Larsen, L. O., Andersen, Anne Poder, Counillon, L. & Pedersen, Stine Helene Falsig, 2020, In: Scientific Reports. 10, 17 p., 5800.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    The Acidic Tumor Microenvironment as a Driver of Cancer

    Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2020, In: Annual Review of Physiology. 82, p. 103-126

    Research output: Contribution to journalReviewpeer-review

  33. Published

    The Vacuolar H+ ATPase α3 Subunit Negatively Regulates Migration and Invasion of Human Pancreatic Ductal Adenocarcinoma Cells

    Flinck, M., Hagelund, S., Gorbatenko, A., Severin, M., Pedraz-Cuesta, E., Novak, Ivana, Stock, C. & Pedersen, Stine Helene Falsig, 2020, In: Cells. 9, 2, 22 p., 465.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Why Warburg Works: Lactate Controls Immune Evasion through GPR81

    Jørgensen, Kathrine Lundø, Trauelsen, Mette, Pedersen, Stine Helene Falsig & Schwartz, Thue W., 2020, In: Cell Metabolism. 31, 4, p. 666–668 3 p.

    Research output: Contribution to journalLetterpeer-review

  35. Published

    Yeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies

    Kassem, N., Kassem, M. M., Pedersen, Stine Helene Falsig, Pedersen, Per Amstrup & Kragelund, Birthe Brandt, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 14 p., 183272.

    Research output: Contribution to journalJournal articlepeer-review

  36. 2019
  37. Published

    3D multicellular models to study the regulation and roles of acid-base transporters in breast cancer

    Czaplinska, D., Elingaard-Larsen, L. O., Rolver, M. G., Severin, M. & Pedersen, Stine Helene Falsig, 20 Dec 2019, In: Biochemical Society Transactions. 47, 6, p. 1689-1700 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer

    Avnet, S., Baldini, N., Brisson, L., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Szabadkai, G. & Pastorekova, S., 2019, In: Frontiers in Oncology. 9, 5 p., 1332.

    Research output: Contribution to journalReviewpeer-review

  39. Published

    Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

    Rolver, M. G., Elingaard-Larsen, L. O. & Pedersen, Stine Helene Falsig, 2019, In: Journal of Visualized Experiments. 2019, 148, e59714.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

    Tornabene, E., Helms, H. C. C., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2019, In: PLoS ONE. 14, 8, 20 p., e0221103.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

    Gorbatenko, A., Søkilde, R., Sorensen, E. E., Newie, I., Persson, H., Morancho, B., Arribas, J., Litman, Thomas, Rovira, C. & Pedersen, Stine Helene Falsig, 2019, In: Scientific Reports. 9, 1, p. 1-16 3352.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin

    Hendus-Altenburger, R., Wang, X., Sjøgaard-Frich, Lise Margrethe, Pedraz Cuesta, E., Sheftic, S. R., Bendsøe, A. H., Page, R., Kragelund, Birthe Brandt, Pedersen, Stine Helene Falsig & Peti, W., 2019, In: Nature Communications. 10, 13 p., 3489.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Profibrotic epithelial phenotype: a central role for MRTF and TAZ

    Bialik, J. F., Ding, M., Speight, P., Dan, Q., Miranda, M. Z., Di Ciano-Oliveira, C., Kofler, M. M., Rotstein, O. D., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2019, In: Scientific Reports. 9, p. 1-14 4323.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    The Na+/H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration

    Jensen, H. H., Pedersen, G. A., Morgen, J. J., Parsons, M., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2019, In: Journal of Physiology. 597, 3, p. 849-867

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    The SLC9A-C Mammalian Na+/H+ Exchanger Family: Molecules, Mechanisms, and Physiology

    Pedersen, Stine Helene Falsig & Counillon, L., 2019, In: Physiological Reviews. 99, 4, p. 2015-2113 99 p.

    Research output: Contribution to journalReviewpeer-review

  46. 2018
  47. Published

    Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

    Lee, S., Axelsen, T. V., Jesse, N., Pedersen, Stine Helene Falsig, Vahl, P. & Boedtkjer, E., 2018, In: Oncogene. 37, 41, p. 5569-5584

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Roles of pH in control of cell proliferation

    Flinck, M., Kramer, S. H. & Pedersen, Stine Helene Falsig, 2018, In: Acta Physiologica. 223, 3, p. 1-17 e13068.

    Research output: Contribution to journalReviewpeer-review

  49. Published

    The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells

    Flinck, M., Kramer, S. H., Schnipper, J., Andersen, Anne Poder & Pedersen, Stine Helene Falsig, 2018, In: Cell Cycle. 17, 9, p. 1056-1067

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

    Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Trafficking, localization and degradation of the Na+,HCO3- Co-transporter NBCn1 in kidney and breast epithelial cells

    Olesen, C. W., Vogensen, J., Axholm, I., Severin, M., Schnipper, J., Pedersen, I. S., von Stemann, J. H., Schrøder, J. M., Christensen, D. P. & Pedersen, Stine Helene Falsig, 2018, In: Scientific Reports. 8, p. 1-16 7435.

    Research output: Contribution to journalJournal articlepeer-review

  52. 2017
  53. Published

    MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism

    Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, Marie Sophie, Markussen, L. K., Viuff, B. M., Lambert, Ian Henry, Hansen, Jacob B. & Pedersen, Stine Helene Falsig, 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)

    Hendus-Altenburger, R., Lambrughi, M., Terkelsen, Thilde Bagger, Pedersen, Stine Helene Falsig, Papaleo, E., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Sep 2017, In: Cellular Signalling. 37, p. 40-51 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer

    Baldini, N., de Milito, A., Feron, O., Gillies, R. J., Michiels, C., Otto, A. M., Pastoreková, S., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Supuran, C. T. & Avnet, S., 4 Jul 2017, In: Frontiers in Pharmacology. 8, 5 p., 411.

    Research output: Contribution to journalComment/debate

  56. Published

    Alternating pH landscapes shape epithelial cancer initiation and progression: focus on pancreatic cancer

    Pedersen, Stine Helene Falsig, Novak, Ivana, Alves, F., Schwab, A. & Pardo, L. A., Jun 2017, In: BioEssays. 39, 6, 10 p., 1600253.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Roles of pH and the Na+/H+ exchanger NHE1 in cancer: from cell biology and animal models to an emerging translational perspective?

    Stock, C. & Pedersen, Stine Helene Falsig, Apr 2017, In: Seminars in Cancer Biology. 43, p. 5-16 12 p.

    Research output: Contribution to journalReviewpeer-review

  58. Published

    TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

    Miranda, M. Z., Bialik, J. F., Speight, P., Dan, Q., Yeung, T., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2017, In: Journal of Biological Chemistry. 292, 36, p. 14902-14920 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published
  60. 2016
  61. Published

    Modeling the ischemic blood-brain barrier; the effects of oxygen-glucose deprivation (OGD) on endothelial cells in culture

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 19 Jun 2016.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  62. Published

    HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5

    Newie, I., Søkilde, R., Persson, H., Jacomasso, T., Gorbatenko, A., Borg, Å., de Hoon, M., Pedersen, Stine Helene Falsig & Rovira, C., 2016, In: Scientific Reports. 6, 10 p., 35664.

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016.

    Research output: Contribution to conferencePosterResearch

  64. Published

    Assessment of different 3D culture systems to study tumor phenotype and chemosensitivity in pancreatic ductal adenocarcinoma

    Zeeberg, K., Cardone, R. A., Greco, M. R., Saccomano, M., Nøhr-Nielsen, A., Alves, F., Pedersen, Stine Helene Falsig & Reshkin, S. J., 2016, In: International Journal of Oncology. 49, 1, p. 243-252 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    Biophysics and physiology of the volume-regulated anion channel (VRAC)/volume-sensitive outwardly rectifying anion channel (VSOR)

    Pedersen, Stine Helene Falsig, Okada, Y. & Nilius, B., 2016, In: Pflügers Archiv - European Journal of Physiology. 468, 3, p. 371-383 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Disrupting Na+,HCO3--cotransporter NBCn1 (Slc4a7) delays murine breast cancer development

    Lee, S., Axelsen, T. V., Andersen, Anne Poder, Vahl, P., Pedersen, Stine Helene Falsig & Bødtkjer, E. B., 2016, In: Oncogene. 35, 16, p. 2112–2122 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Glycosylation of solute carriers: mechanisms and functional consequences

    Pedersen, N. B., Carlsson, M. C. & Pedersen, Stine Helene Falsig, 2016, In: Pflügers Archiv - European Journal of Physiology. 468, 2, p. 159-176 18 p.

    Research output: Contribution to journalReviewpeer-review

  68. Published

    Metabolism and microenvironment in cancer plasticity

    Baldini, N., Sonveaux, P., De Milito, A., Supuran, C. T., Otto, A. M., Stock, C. M., Pedersen, Stine Helene Falsig, Favicchio, R. & Avnet, S., 2016, In: Cancer & Metabolism. 4, Supplement 1, 7 p., 1.

    Research output: Contribution to journalComment/debate

  69. Published

    Monocarboxylate transporters MCT1 and MCT4 regulate migration and invasion of pancreatic ductal adenocarcinoma cells

    Kong, S. C., Nøhr-Nielsen, A., Zeeberg, K., Reshkin, S. J., Hoffmann, E. K., Novak, Ivana & Pedersen, Stine Helene Falsig, 2016, In: Pancreas. 45, 7, p. 1036-1047 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Myocardin-related transcription factor regulates Nox4 protein expression: linking cytoskeletal orginization to redox state

    Rozycki, M., Bialik, J. F., Speight, P., Dan, Q., Knudsen, Teresa Emmilie Toudal, Szeto, S. G., Yuen, D. A., Szászi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2016, In: Journal of Biological Chemistry. 291, 1, p. 227-243 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes

    Gorbatenko, A., Olesen, C. W., Loebl, N., Sigurdsson, H. H., Bianchi, C., Pedraz Cuesta, E., Christiansen, Jan & Pedersen, Stine Helene Falsig, 2016, In: Biochemical Journal. 473, 21, p. 4027-4044 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  72. Published

    Prolactin signaling stimulates invasion via Na+/H+ exchanger NHE1 in T47D human breast cancer cells

    Pedraz Cuesta, E., Fredsted, J., Jensen, H. H., Bornebusch, A., Nejsum, L. N., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2016, In: Molecular Endocrinology. 30, 7, p. 693-708 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment

    Andersen, Anne Poder, Flinck, M., Oernbo, E. K., Pedersen, N. B., Viuff, B. M. & Pedersen, Stine Helene Falsig, 2016, In: Molecular Cancer. 15, 18 p., 45.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Snowpack fluxes of methane and carbon dioxide from high Arctic tundra

    Pirk, N., Tamstorf, M. P., Lund, M., Mastepanov, M., Pedersen, Stine Helene Falsig, Mylius, M. R., Parmentier, F. W., Christiansen, H. H. & Christensen, T. R., 2016, In: Journal of Geophysical Research: Biogeosciences. 121, 11, p. 2886-2900 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  75. Published

    The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2

    Hendus-Altenburger, R., Pedraz Cuesta, E., Olesen, C. W., Papaleo, E., Schnell, J. A., Hopper, J. T. S., Robinson, C. V., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2016, In: BMC Biology. 14, 17 p., 31.

    Research output: Contribution to journalJournal articlepeer-review

  76. 2015
  77. Published

    The in vitro blood-brain barrier model under OGD condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  78. Published

    Changes in barrier properties and protein expression levels of bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 27 Aug 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  79. Published

    Changes in protein expression levels, Claudin-5 localization and barrier function in bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 4 Jul 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  80. Published

    ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

    Sauter, D. R. P., Novak, Ivana, Pedersen, Stine Helene Falsig, Larsen, Erik Hviid & Hoffmann, E. K., 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1495-1508 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published

    Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

    Sigurðsson, H. H., Olesen, C. W., Dybboe, R., Lauritzen, G. & Pedersen, Stine Helene Falsig, 2015, In: Molecular Cancer Research. 13, 1, p. 63-77 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells

    Rasmussen, L. J. H., Mûller, H. S. H., Jørgensen, B., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2015, In: American Journal of Physiology: Cell Physiology. 308, 2, p. C101-C110 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

    Nadeem, A., Sanborn, J., Gettel, D. L., Ho C.S., J., Rydström, A., Ngassam, V. N., Klausen, T. K., Pedersen, Stine Helene Falsig, Lam, M., Parikh, A. N. & Svanborg, C., 2015, In: Scientific Reports. 5, 14 p., 16432.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

    Giannuzzo, A., Pedersen, Stine Helene Falsig & Novak, Ivana, 2015, In: Molecular Cancer. 14, 15 p., 203.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    The identification of a volume-regulated anion channel: an amazing Odyssey

    Pedersen, Stine Helene Falsig, Klausen, T. K. & Nilius, B., 2015, In: Acta Physiologica (Print). 213, 4, p. 868-881 14 p.

    Research output: Contribution to journalReviewpeer-review

  89. 2014
  90. Published

    Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential

    Kong, S. C., Giannuzzo, A., Novak, Ivana & Pedersen, Stine Helene Falsig, 2014, In: Biochemistry and Cell Biology. 92, 6, p. 449-459 11 p.

    Research output: Contribution to journalReviewpeer-review

  91. Published

    Characteristics of summer-time energy exchange in a high Arctic tundra heath 2000-2010

    Lund, M., Hansen, Birger, Pedersen, Stine Helene Falsig, Stiegler, C. & Tamstorf, M. P., 2014, In: Tellus B: Chemical and Physical Meteorology. 66

    Research output: Contribution to journalJournal articlepeer-review

  92. Published

    ErbB2 upregulates the Na+,HCO3- -cotransporter NBCn1/SLC4A7 in human breast cancer cells via Akt, ERK, Src, and Krüppel-like factor 4

    Gorbatenko, A., Olesen, C. W., Mørup, N., Thiel, G., Kallunki, T., Valen, E. & Pedersen, Stine Helene Falsig, 2014, In: F A S E B Journal. 28, 1, p. 350-363 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  93. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair

    Schreml, S., Meier, R. J., Kirschbaum, M., Kong, S. C., Gehmert, S., Felthaus, O., Kuechler, S., Sharpe, J. R., Woeltje, K., Weiss, K. T., Albert, M., Seidl, U., Schroeder, J., Morsczeck, C., Prantl, L., Duschl, C., Pedersen, S. H. F., Gosau, M., Berneburg, M., Wolfbeis, O. S. & 2 others, Landthaler, M. & Babilas, P., 2014, In: Theranostics. 4, 7, p. 721-735 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  95. Published

    Regulation and roles of bicarbonate transporters in cancer

    Gorbatenko, A., Olesen, C. W., Bødtkjer, E. & Pedersen, Stine Helene Falsig, 2014, In: Frontiers in Physiology. 5, 15 p., 130.

    Research output: Contribution to journalJournal articlepeer-review

  96. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers

    Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  98. 2013
  99. Published

    A unifying mechanism for Cancer cell death through ion channel activation by HAMLET

    Storm, P., Klausen, T. K., Trulsson, M., Ho CS, J., Dosnon, M., Westergren, T., Chao, Y., Rydström, A., Yang, H., Pedersen, Stine Helene Falsig & Svanborg, C., 2013, In: P L o S One. 8, 3, 18 p., e58578.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Cell volume regulation in epithelial physiology and cancer

    Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Novak, Ivana, 2013, In: Frontiers in Physiology. 4, 12 p., 233.

    Research output: Contribution to journalReviewpeer-review

  101. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  102. Published

    Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

    Ly, D. L., Waheed, F., Lodyga, M., Speight, P., Masszi, A., Nakano, H., Hersom, M. N. S., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2013, In: American Journal of Physiology: Cell Physiology. 304, 2, p. C115-C127 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  103. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journalJournal articlepeer-review

  104. Published

    Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential

    Pedersen, Stine Helene Falsig & Stock, C., 2013, In: Cancer Research. 73, 6, p. 1658-1661 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  105. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  106. 2012
  107. Published

    Gram-scale solution-phase synthesis of selective sodium bicarbonate Co-transport Inhibitor S0859: in vitro efficacy studies in breast cancer cells

    Larsen, A. M., Krogsgaard-Larsen, N., Lauritzen, G., Olesen, C. W., Hansen, S. H., Bødtkjer, E., Pedersen, Stine Helene Falsig & Bunch, Lennart, 2012, In: ChemMedChem. 7, 10, p. 1808-1814 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  108. Published

    On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle

    Madsen, C. P., Klausen, T. K., Fabian, A., Hansen, B. J., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2012, In: American Journal of Physiology: Cell Physiology. 303, 6, p. C625-C634 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  109. Published

    Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

    Bødtkjer, E., Bunch, Lennart & Pedersen, Stine Helene Falsig, 2012, In: Current Pharmaceutical Design. 18, 10, p. 1345-1371 27 p.

    Research output: Contribution to journalJournal articlepeer-review

  110. Published

    The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2

    Lauritzen, G., Stock, C., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., Petersen, K. S., Wiwel, M., Rønnov-Jessen, Lone, Schwab, A. & Pedersen, Stine Helene Falsig, 2012, In: Cancer Letters. 317, 2, p. 172-183 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  111. 2011
  112. Published

    Cell volume homeostatic mechanisms: effectors and signalling pathways

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 27 Jan 2011, In: Acta Physiologica. 202, 3, p. 465–485

    Research output: Contribution to journalJournal articlepeer-review

  113. Published

    Cell Volume Regulation and Signaling in 3T3-L1 Pre-adipocytes and Adipocytes: on the Possible Roles of Caveolae, Insulin Receptors, FAK and ERK1/2

    Eduardsen, K., Larsen, S., Novak, Ivana, Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1231-46 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  114. Published

    EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

    Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.

    Research output: Contribution to journalJournal articlepeer-review

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