3did: a catalog of domain-based interactions of known three-dimensional structure
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3did : a catalog of domain-based interactions of known three-dimensional structure. / Mosca, Roberto; Céol, Arnaud; Stein, Amelie; Olivella, Roger; Aloy, Patrick.
In: Nucleic Acids Research, Vol. 42, No. D1, 2014, p. D374-D379.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - 3did
T2 - a catalog of domain-based interactions of known three-dimensional structure
AU - Mosca, Roberto
AU - Céol, Arnaud
AU - Stein, Amelie
AU - Olivella, Roger
AU - Aloy, Patrick
PY - 2014
Y1 - 2014
N2 - The database of 3D interacting domains (3did, available online for browsing and bulk download at http://3did.irbbarcelona.org) is a catalog of protein-protein interactions for which a high-resolution 3D structure is known. 3did collects and classifies all structural templates of domain-domain interactions in the Protein Data Bank, providing molecular details for such interactions. The current version also includes a pipeline for the discovery and annotation of novel domain-motif interactions. For every interaction, 3did identifies and groups different binding modes by clustering similar interfaces into 'interaction topologies'. By maintaining a constantly updated collection of domain-based structural interaction templates, 3did is a reference source of information for the structural characterization of protein interaction networks. 3did is updated every 6 months.
AB - The database of 3D interacting domains (3did, available online for browsing and bulk download at http://3did.irbbarcelona.org) is a catalog of protein-protein interactions for which a high-resolution 3D structure is known. 3did collects and classifies all structural templates of domain-domain interactions in the Protein Data Bank, providing molecular details for such interactions. The current version also includes a pipeline for the discovery and annotation of novel domain-motif interactions. For every interaction, 3did identifies and groups different binding modes by clustering similar interfaces into 'interaction topologies'. By maintaining a constantly updated collection of domain-based structural interaction templates, 3did is a reference source of information for the structural characterization of protein interaction networks. 3did is updated every 6 months.
KW - Databases, Protein
KW - Internet
KW - Models, Molecular
KW - Protein Interaction Domains and Motifs
KW - Protein Interaction Mapping
KW - Protein Interaction Maps
U2 - 10.1093/nar/gkt887
DO - 10.1093/nar/gkt887
M3 - Journal article
C2 - 24081580
VL - 42
SP - D374-D379
JO - Nucleic Acids Research
JF - Nucleic Acids Research
SN - 0305-1048
IS - D1
ER -
ID: 203256401