7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry. / Kirpekar, F.; Nordhoff, E.; Kristiansen, Karsten; Roepstorff, P.; Hahner, S.; Hillenkamp, F.

In: Rapid Communications in Mass Spectrometry, Vol. 9, No. 6, 1995, p. 525 - 531.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kirpekar, F, Nordhoff, E, Kristiansen, K, Roepstorff, P, Hahner, S & Hillenkamp, F 1995, '7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry', Rapid Communications in Mass Spectrometry, vol. 9, no. 6, pp. 525 - 531. https://doi.org/10.1002/rcm.1290090611

APA

Kirpekar, F., Nordhoff, E., Kristiansen, K., Roepstorff, P., Hahner, S., & Hillenkamp, F. (1995). 7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Communications in Mass Spectrometry, 9(6), 525 - 531. https://doi.org/10.1002/rcm.1290090611

Vancouver

Kirpekar F, Nordhoff E, Kristiansen K, Roepstorff P, Hahner S, Hillenkamp F. 7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Communications in Mass Spectrometry. 1995;9(6):525 - 531. https://doi.org/10.1002/rcm.1290090611

Author

Kirpekar, F. ; Nordhoff, E. ; Kristiansen, Karsten ; Roepstorff, P. ; Hahner, S. ; Hillenkamp, F. / 7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry. In: Rapid Communications in Mass Spectrometry. 1995 ; Vol. 9, No. 6. pp. 525 - 531.

Bibtex

@article{5d2347200f1011de8478000ea68e967b,
title = "7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry",
abstract = "Oligodeoxynucleotides which contain 7-deaza analogues of the normal purine nucleotides have been synthesized both enzymatically and chemically. When subjected to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis, the modified samples offer both higher stability and increased sensitivity compared to otherwise identical unmodified Oligodeoxynucleotides. In view of these observations, models for the fragmentation of oligodeoxynucleotides in MALDI-MS with positive ion detection mode are presented. Additionally, the potential use of 7-deaza purine nucleotides in the MALDI-MS analysis of DNA sequencing reactions is discussed.",
author = "F. Kirpekar and E. Nordhoff and Karsten Kristiansen and P. Roepstorff and S. Hahner and F. Hillenkamp",
year = "1995",
doi = "10.1002/rcm.1290090611",
language = "English",
volume = "9",
pages = "525 -- 531",
journal = "Rapid Communications in Mass Spectrometry",
issn = "0951-4198",
publisher = "JohnWiley & Sons Ltd",
number = "6",

}

RIS

TY - JOUR

T1 - 7-Deaza purine bases offer a higher ion stability in the analysis of dna by matrix-assisted laser desorption/ionization mass spectrometry

AU - Kirpekar, F.

AU - Nordhoff, E.

AU - Kristiansen, Karsten

AU - Roepstorff, P.

AU - Hahner, S.

AU - Hillenkamp, F.

PY - 1995

Y1 - 1995

N2 - Oligodeoxynucleotides which contain 7-deaza analogues of the normal purine nucleotides have been synthesized both enzymatically and chemically. When subjected to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis, the modified samples offer both higher stability and increased sensitivity compared to otherwise identical unmodified Oligodeoxynucleotides. In view of these observations, models for the fragmentation of oligodeoxynucleotides in MALDI-MS with positive ion detection mode are presented. Additionally, the potential use of 7-deaza purine nucleotides in the MALDI-MS analysis of DNA sequencing reactions is discussed.

AB - Oligodeoxynucleotides which contain 7-deaza analogues of the normal purine nucleotides have been synthesized both enzymatically and chemically. When subjected to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis, the modified samples offer both higher stability and increased sensitivity compared to otherwise identical unmodified Oligodeoxynucleotides. In view of these observations, models for the fragmentation of oligodeoxynucleotides in MALDI-MS with positive ion detection mode are presented. Additionally, the potential use of 7-deaza purine nucleotides in the MALDI-MS analysis of DNA sequencing reactions is discussed.

U2 - 10.1002/rcm.1290090611

DO - 10.1002/rcm.1290090611

M3 - Journal article

VL - 9

SP - 525

EP - 531

JO - Rapid Communications in Mass Spectrometry

JF - Rapid Communications in Mass Spectrometry

SN - 0951-4198

IS - 6

ER -

ID: 11231924