Immunmodulerende effekt af LongoVital hos patienter med recidiverende aftøs stomatit. 2
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Immunmodulerende effekt af LongoVital hos patienter med recidiverende aftøs stomatit. 2. / Pedersen, A; Klausen, B; Hougen, H P; Ryder, L; Winther, K.
In: Ugeskrift for Laeger, Vol. 153, No. 37, 1991, p. 2561-4.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Immunmodulerende effekt af LongoVital hos patienter med recidiverende aftøs stomatit. 2
AU - Pedersen, A
AU - Klausen, B
AU - Hougen, H P
AU - Ryder, L
AU - Winther, K
PY - 1991
Y1 - 1991
N2 - LongoVital (LV) (DK. reg. no. 5178/75) is a herbal-based tablet enriched with recommended doses of vitamins. Peripheral lymphocyte subsets: T-helper/CD4 (OKT4+) and T-suppressor/cytotoxic/CD8 (OKT8+) were studied quantitatively in 31 otherwise healthy patients with minor recurrent aphthous ulceration (RAU) during six months' daily LV intake in a double-blind, randomised, crossover 1-year study. Fourteen had had LV during the first six months (GrA) and 17 LV during the latter six months (GrB). OKT4+ percentages increased significantly during the LV period in both groups (p less than 0.05). OKT8+ percentages increased in both groups, however, only significantly in GrA (P less than 0.05). It is concluded that LV acts as an immunostimulator in patients with RAU and that the increase in T-lymphocyte subsets may account for the previously reported benefit of LV in RAU prevention.
AB - LongoVital (LV) (DK. reg. no. 5178/75) is a herbal-based tablet enriched with recommended doses of vitamins. Peripheral lymphocyte subsets: T-helper/CD4 (OKT4+) and T-suppressor/cytotoxic/CD8 (OKT8+) were studied quantitatively in 31 otherwise healthy patients with minor recurrent aphthous ulceration (RAU) during six months' daily LV intake in a double-blind, randomised, crossover 1-year study. Fourteen had had LV during the first six months (GrA) and 17 LV during the latter six months (GrB). OKT4+ percentages increased significantly during the LV period in both groups (p less than 0.05). OKT8+ percentages increased in both groups, however, only significantly in GrA (P less than 0.05). It is concluded that LV acts as an immunostimulator in patients with RAU and that the increase in T-lymphocyte subsets may account for the previously reported benefit of LV in RAU prevention.
KW - Adult
KW - Double-Blind Method
KW - Female
KW - Humans
KW - Leukocyte Count
KW - Male
KW - Middle Aged
KW - Plant Extracts
KW - Recurrence
KW - Stomatitis, Aphthous
KW - T-Lymphocytes
KW - Tablets
KW - Vitamins
M3 - Tidsskriftartikel
C2 - 1949258
VL - 153
SP - 2561
EP - 2564
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 37
ER -
ID: 44355025