Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization

Research output: Contribution to journalReviewpeer-review

Standard

Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization. / Liu, Wenzheng; Røder, Henriette Lyng; Madsen, Jonas Stenløkke; Bjarnsholt, Thomas; Sørensen, Søren Johannes; Burmølle, Mette.

In: Frontiers in Microbiology, Vol. 7, 1366, 2016.

Research output: Contribution to journalReviewpeer-review

Harvard

Liu, W, Røder, HL, Madsen, JS, Bjarnsholt, T, Sørensen, SJ & Burmølle, M 2016, 'Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization', Frontiers in Microbiology, vol. 7, 1366. https://doi.org/10.3389/fmicb.2016.01366

APA

Liu, W., Røder, H. L., Madsen, J. S., Bjarnsholt, T., Sørensen, S. J., & Burmølle, M. (2016). Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization. Frontiers in Microbiology, 7, [1366]. https://doi.org/10.3389/fmicb.2016.01366

Vancouver

Liu W, Røder HL, Madsen JS, Bjarnsholt T, Sørensen SJ, Burmølle M. Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization. Frontiers in Microbiology. 2016;7. 1366. https://doi.org/10.3389/fmicb.2016.01366

Author

Liu, Wenzheng ; Røder, Henriette Lyng ; Madsen, Jonas Stenløkke ; Bjarnsholt, Thomas ; Sørensen, Søren Johannes ; Burmølle, Mette. / Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization. In: Frontiers in Microbiology. 2016 ; Vol. 7.

Bibtex

@article{f34670d97ef34d65af1c85bbffed3fc1,
title = "Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization",
abstract = "Interspecies interactions are essential for the persistence and development of any kind of complex community, and microbial biofilms are no exception. Multispecies biofilms are structured and spatially defined communities that have received much attention due to their omnipresence in natural environments. Species residing in these complex bacterial communities usually interact both intra- and interspecifically. Such interactions are considered to not only be fundamental in shaping overall biomass and the spatial distribution of cells residing in multispecies biofilms, but also to result in coordinated regulation of gene expression in the different species present. These communal interactions often lead to emergent properties in biofilms, such as enhanced tolerance against antibiotics, host immune responses, and other stresses, which have been shown to provide benefits to all biofilm members not only the enabling sub-populations. However, the specific molecular mechanisms of cellular processes affecting spatial organization, and vice versa, are poorly understood and very complex to unravel. Therefore, detailed description of the spatial organization of individual bacterial cells in multispecies communities can be an alternative strategy to reveal the nature of interspecies interactions of constituent species. Closing the gap between visual observation and biological processes may become crucial for resolving biofilm related problems, which is of utmost importance to environmental, industrial, and clinical implications. This review briefly presents the state of the art of studying interspecies interactions and spatial organization of multispecies communities, aiming to support theoretical and practical arguments for further advancement of this field.",
keywords = "Interspecies interactions, Multispecies biofilms, Spatial organization",
author = "Wenzheng Liu and R{\o}der, {Henriette Lyng} and Madsen, {Jonas Stenl{\o}kke} and Thomas Bjarnsholt and S{\o}rensen, {S{\o}ren Johannes} and Mette Burm{\o}lle",
year = "2016",
doi = "10.3389/fmicb.2016.01366",
language = "English",
volume = "7",
journal = "Frontiers in Microbiology",
issn = "1664-302X",
publisher = "Frontiers Media S.A.",

}

RIS

TY - JOUR

T1 - Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization

AU - Liu, Wenzheng

AU - Røder, Henriette Lyng

AU - Madsen, Jonas Stenløkke

AU - Bjarnsholt, Thomas

AU - Sørensen, Søren Johannes

AU - Burmølle, Mette

PY - 2016

Y1 - 2016

N2 - Interspecies interactions are essential for the persistence and development of any kind of complex community, and microbial biofilms are no exception. Multispecies biofilms are structured and spatially defined communities that have received much attention due to their omnipresence in natural environments. Species residing in these complex bacterial communities usually interact both intra- and interspecifically. Such interactions are considered to not only be fundamental in shaping overall biomass and the spatial distribution of cells residing in multispecies biofilms, but also to result in coordinated regulation of gene expression in the different species present. These communal interactions often lead to emergent properties in biofilms, such as enhanced tolerance against antibiotics, host immune responses, and other stresses, which have been shown to provide benefits to all biofilm members not only the enabling sub-populations. However, the specific molecular mechanisms of cellular processes affecting spatial organization, and vice versa, are poorly understood and very complex to unravel. Therefore, detailed description of the spatial organization of individual bacterial cells in multispecies communities can be an alternative strategy to reveal the nature of interspecies interactions of constituent species. Closing the gap between visual observation and biological processes may become crucial for resolving biofilm related problems, which is of utmost importance to environmental, industrial, and clinical implications. This review briefly presents the state of the art of studying interspecies interactions and spatial organization of multispecies communities, aiming to support theoretical and practical arguments for further advancement of this field.

AB - Interspecies interactions are essential for the persistence and development of any kind of complex community, and microbial biofilms are no exception. Multispecies biofilms are structured and spatially defined communities that have received much attention due to their omnipresence in natural environments. Species residing in these complex bacterial communities usually interact both intra- and interspecifically. Such interactions are considered to not only be fundamental in shaping overall biomass and the spatial distribution of cells residing in multispecies biofilms, but also to result in coordinated regulation of gene expression in the different species present. These communal interactions often lead to emergent properties in biofilms, such as enhanced tolerance against antibiotics, host immune responses, and other stresses, which have been shown to provide benefits to all biofilm members not only the enabling sub-populations. However, the specific molecular mechanisms of cellular processes affecting spatial organization, and vice versa, are poorly understood and very complex to unravel. Therefore, detailed description of the spatial organization of individual bacterial cells in multispecies communities can be an alternative strategy to reveal the nature of interspecies interactions of constituent species. Closing the gap between visual observation and biological processes may become crucial for resolving biofilm related problems, which is of utmost importance to environmental, industrial, and clinical implications. This review briefly presents the state of the art of studying interspecies interactions and spatial organization of multispecies communities, aiming to support theoretical and practical arguments for further advancement of this field.

KW - Interspecies interactions

KW - Multispecies biofilms

KW - Spatial organization

U2 - 10.3389/fmicb.2016.01366

DO - 10.3389/fmicb.2016.01366

M3 - Review

C2 - 27630624

AN - SCOPUS:84989324696

VL - 7

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

SN - 1664-302X

M1 - 1366

ER -

ID: 168934156