R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes
Research output: Contribution to journal › Journal article › Research › peer-review
A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.
| Original language | English |
|---|---|
| Journal | Anticancer Research |
| Volume | 10 |
| Issue number | 2A |
| Pages (from-to) | 375-7 |
| Number of pages | 2 |
| ISSN | 0250-7005 |
| Publication status | Published - 1990 |
| Externally published | Yes |
Bibliographical note
Keywords: Chromosome Banding; Chromosome Mapping; Chromosomes, Human, Pair 2; Humans; Nucleic Acid Hybridization; Oncogenes; X Chromosome
ID: 11368422