β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?
Publikation: Bidrag til tidsskrift › Leder › Forskning › fagfællebedømt
Type 2 diabetes is a progressive disorder, but exactly how the progression occurs remains unknown. In this issue of Cell Metabolism, Zhang et al. (2019) present evidence that diabetes, via hyperglycemia, leads to aberrant insertion of a mitochondrial ion channel in the plasma membrane, rendering it leaky to key intracellular signaling molecules with resultant suppression of insulin secretion.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Cell Metabolism |
Vol/bind | 29 |
Udgave nummer | 1 |
Sider (fra-til) | 1-2 |
Antal sider | 2 |
ISSN | 1550-4131 |
DOI | |
Status | Udgivet - 2019 |
Eksternt udgivet | Ja |
Bibliografisk note
Copyright © 2018 Elsevier Inc. All rights reserved.
ID: 227695071