Control of bacterial chromosome replication by non-coding regions outside the origin

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Control of bacterial chromosome replication by non-coding regions outside the origin. / Frimodt-Møller, Jakob; Charbon, Godefroid; Løbner-Olesen, Anders.

I: Current Genetics, Bind 63, Nr. 4, 2017, s. 607-611.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Frimodt-Møller, J, Charbon, G & Løbner-Olesen, A 2017, 'Control of bacterial chromosome replication by non-coding regions outside the origin', Current Genetics, bind 63, nr. 4, s. 607-611. https://doi.org/10.1007/s00294-016-0671-6

APA

Frimodt-Møller, J., Charbon, G., & Løbner-Olesen, A. (2017). Control of bacterial chromosome replication by non-coding regions outside the origin. Current Genetics, 63(4), 607-611. https://doi.org/10.1007/s00294-016-0671-6

Vancouver

Frimodt-Møller J, Charbon G, Løbner-Olesen A. Control of bacterial chromosome replication by non-coding regions outside the origin. Current Genetics. 2017;63(4):607-611. https://doi.org/10.1007/s00294-016-0671-6

Author

Frimodt-Møller, Jakob ; Charbon, Godefroid ; Løbner-Olesen, Anders. / Control of bacterial chromosome replication by non-coding regions outside the origin. I: Current Genetics. 2017 ; Bind 63, Nr. 4. s. 607-611.

Bibtex

@article{95cb8ac74d234dc48886bb4527abd5ea,
title = "Control of bacterial chromosome replication by non-coding regions outside the origin",
abstract = "Chromosome replication in Eubacteria is initiated by initiator protein(s) binding to specific sites within the replication origin, oriC. Recently, initiator protein binding to chromosomal regions outside the origin has attracted renewed attention; as such binding sites contribute to control the frequency of initiations. These outside-oriC binding sites function in several different ways: by steric hindrances of replication fork assembly, by titration of initiator proteins away from the origin, by performing a chaperone-like activity for inactivation- or activation of initiator proteins or by mediating crosstalk between chromosomes. Here, we discuss initiator binding to outside-oriC sites in a broad range of different taxonomic groups, to highlight the significance of such regions for regulation of bacterial chromosome replication. For Escherichia coli, it was recently shown that the genomic positions of regulatory elements are important for bacterial fitness, which, as we discuss, could be true for several other organisms.",
author = "Jakob Frimodt-M{\o}ller and Godefroid Charbon and Anders L{\o}bner-Olesen",
year = "2017",
doi = "10.1007/s00294-016-0671-6",
language = "English",
volume = "63",
pages = "607--611",
journal = "Current Genetics",
issn = "0172-8083",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - Control of bacterial chromosome replication by non-coding regions outside the origin

AU - Frimodt-Møller, Jakob

AU - Charbon, Godefroid

AU - Løbner-Olesen, Anders

PY - 2017

Y1 - 2017

N2 - Chromosome replication in Eubacteria is initiated by initiator protein(s) binding to specific sites within the replication origin, oriC. Recently, initiator protein binding to chromosomal regions outside the origin has attracted renewed attention; as such binding sites contribute to control the frequency of initiations. These outside-oriC binding sites function in several different ways: by steric hindrances of replication fork assembly, by titration of initiator proteins away from the origin, by performing a chaperone-like activity for inactivation- or activation of initiator proteins or by mediating crosstalk between chromosomes. Here, we discuss initiator binding to outside-oriC sites in a broad range of different taxonomic groups, to highlight the significance of such regions for regulation of bacterial chromosome replication. For Escherichia coli, it was recently shown that the genomic positions of regulatory elements are important for bacterial fitness, which, as we discuss, could be true for several other organisms.

AB - Chromosome replication in Eubacteria is initiated by initiator protein(s) binding to specific sites within the replication origin, oriC. Recently, initiator protein binding to chromosomal regions outside the origin has attracted renewed attention; as such binding sites contribute to control the frequency of initiations. These outside-oriC binding sites function in several different ways: by steric hindrances of replication fork assembly, by titration of initiator proteins away from the origin, by performing a chaperone-like activity for inactivation- or activation of initiator proteins or by mediating crosstalk between chromosomes. Here, we discuss initiator binding to outside-oriC sites in a broad range of different taxonomic groups, to highlight the significance of such regions for regulation of bacterial chromosome replication. For Escherichia coli, it was recently shown that the genomic positions of regulatory elements are important for bacterial fitness, which, as we discuss, could be true for several other organisms.

U2 - 10.1007/s00294-016-0671-6

DO - 10.1007/s00294-016-0671-6

M3 - Review

C2 - 27942832

VL - 63

SP - 607

EP - 611

JO - Current Genetics

JF - Current Genetics

SN - 0172-8083

IS - 4

ER -

ID: 171551113