Dynamics of bacterial populations under the feast-famine cycles

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Dynamics of bacterial populations under the feast-famine cycles. / Himeoka, Yusuke; Mitarai, Namiko.

I: Physical Review Research, Bind 2, Nr. 1, 013372, 27.03.2020.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Himeoka, Y & Mitarai, N 2020, 'Dynamics of bacterial populations under the feast-famine cycles', Physical Review Research, bind 2, nr. 1, 013372. https://doi.org/10.1103/PhysRevResearch.2.013372

APA

Himeoka, Y., & Mitarai, N. (2020). Dynamics of bacterial populations under the feast-famine cycles. Physical Review Research, 2(1), [013372]. https://doi.org/10.1103/PhysRevResearch.2.013372

Vancouver

Himeoka Y, Mitarai N. Dynamics of bacterial populations under the feast-famine cycles. Physical Review Research. 2020 mar. 27;2(1). 013372. https://doi.org/10.1103/PhysRevResearch.2.013372

Author

Himeoka, Yusuke ; Mitarai, Namiko. / Dynamics of bacterial populations under the feast-famine cycles. I: Physical Review Research. 2020 ; Bind 2, Nr. 1.

Bibtex

@article{ff4e856f110841b1af5930bf6bf093e4,
title = "Dynamics of bacterial populations under the feast-famine cycles",
abstract = "Bacterial populations in natural conditions are expected to experience stochastic environmental fluctuations, and in addition, environments are affected by bacterial activities since they consume substrates and excrete various chemicals. We here study possible outcomes of population dynamics and evolution under the repeated cycle of substrate-rich conditions and starvation, called the {"}feast-famine cycle,{"} by a simple stochastic model with the trade-off relationship between the growth rate and the growth yield or the death rate. In the model, the feast (substrate-rich) period is led by a stochastic substrate addition event, while the famine (starvation) period is evoked because bacteria use the supplied substrate. Under the repeated feast-famine cycle, the bacterial population tends to increase the growth rate, even though that tends to decrease the total population size due to the trade-off. Analysis of the model shows that the ratio between the growth rate and the death rate becomes the effective fitness of the population. Hence, the functional form of the trade-off between the growth and death rate determines if the bacterial population eventually goes extinct as an evolutionary consequence. We then show that the increase of the added substrate in the feast period can drive the extinction faster. Overall, the model sheds light on nontrivial possible outcomes under repeated feast-famine cycles.",
keywords = "TERM EXPERIMENTAL EVOLUTION, ESCHERICHIA-COLI, TRADE-OFF, KEY INNOVATION, GROWTH-RATE, PERSISTENCE, SURVIVAL, TRAGEDY, STRESS, ADAPTATION",
author = "Yusuke Himeoka and Namiko Mitarai",
year = "2020",
month = mar,
day = "27",
doi = "10.1103/PhysRevResearch.2.013372",
language = "English",
volume = "2",
journal = "Physical Review Research",
issn = "2643-1564",
publisher = "AMER PHYSICAL SOC",
number = "1",

}

RIS

TY - JOUR

T1 - Dynamics of bacterial populations under the feast-famine cycles

AU - Himeoka, Yusuke

AU - Mitarai, Namiko

PY - 2020/3/27

Y1 - 2020/3/27

N2 - Bacterial populations in natural conditions are expected to experience stochastic environmental fluctuations, and in addition, environments are affected by bacterial activities since they consume substrates and excrete various chemicals. We here study possible outcomes of population dynamics and evolution under the repeated cycle of substrate-rich conditions and starvation, called the "feast-famine cycle," by a simple stochastic model with the trade-off relationship between the growth rate and the growth yield or the death rate. In the model, the feast (substrate-rich) period is led by a stochastic substrate addition event, while the famine (starvation) period is evoked because bacteria use the supplied substrate. Under the repeated feast-famine cycle, the bacterial population tends to increase the growth rate, even though that tends to decrease the total population size due to the trade-off. Analysis of the model shows that the ratio between the growth rate and the death rate becomes the effective fitness of the population. Hence, the functional form of the trade-off between the growth and death rate determines if the bacterial population eventually goes extinct as an evolutionary consequence. We then show that the increase of the added substrate in the feast period can drive the extinction faster. Overall, the model sheds light on nontrivial possible outcomes under repeated feast-famine cycles.

AB - Bacterial populations in natural conditions are expected to experience stochastic environmental fluctuations, and in addition, environments are affected by bacterial activities since they consume substrates and excrete various chemicals. We here study possible outcomes of population dynamics and evolution under the repeated cycle of substrate-rich conditions and starvation, called the "feast-famine cycle," by a simple stochastic model with the trade-off relationship between the growth rate and the growth yield or the death rate. In the model, the feast (substrate-rich) period is led by a stochastic substrate addition event, while the famine (starvation) period is evoked because bacteria use the supplied substrate. Under the repeated feast-famine cycle, the bacterial population tends to increase the growth rate, even though that tends to decrease the total population size due to the trade-off. Analysis of the model shows that the ratio between the growth rate and the death rate becomes the effective fitness of the population. Hence, the functional form of the trade-off between the growth and death rate determines if the bacterial population eventually goes extinct as an evolutionary consequence. We then show that the increase of the added substrate in the feast period can drive the extinction faster. Overall, the model sheds light on nontrivial possible outcomes under repeated feast-famine cycles.

KW - TERM EXPERIMENTAL EVOLUTION

KW - ESCHERICHIA-COLI

KW - TRADE-OFF

KW - KEY INNOVATION

KW - GROWTH-RATE

KW - PERSISTENCE

KW - SURVIVAL

KW - TRAGEDY

KW - STRESS

KW - ADAPTATION

U2 - 10.1103/PhysRevResearch.2.013372

DO - 10.1103/PhysRevResearch.2.013372

M3 - Journal article

VL - 2

JO - Physical Review Research

JF - Physical Review Research

SN - 2643-1564

IS - 1

M1 - 013372

ER -

ID: 255159523