Timing of chromosomal replication in Escherichia coli

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Timing of chromosomal replication in Escherichia coli. / Boye, E; Løbner-Olesen, A; Skarstad, K.

I: B B A - Reviews on Cancer, Bind 951, Nr. 2-3, 20.12.1988, s. 359-64.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Boye, E, Løbner-Olesen, A & Skarstad, K 1988, 'Timing of chromosomal replication in Escherichia coli', B B A - Reviews on Cancer, bind 951, nr. 2-3, s. 359-64.

APA

Boye, E., Løbner-Olesen, A., & Skarstad, K. (1988). Timing of chromosomal replication in Escherichia coli. B B A - Reviews on Cancer, 951(2-3), 359-64.

Vancouver

Boye E, Løbner-Olesen A, Skarstad K. Timing of chromosomal replication in Escherichia coli. B B A - Reviews on Cancer. 1988 dec. 20;951(2-3):359-64.

Author

Boye, E ; Løbner-Olesen, A ; Skarstad, K. / Timing of chromosomal replication in Escherichia coli. I: B B A - Reviews on Cancer. 1988 ; Bind 951, Nr. 2-3. s. 359-64.

Bibtex

@article{6e301cf1fa3941ef81ef1f81df239108,
title = "Timing of chromosomal replication in Escherichia coli",
abstract = "We have previously shown that certain mutations in the dnaA and recA genes of Escherichia coli perturb initiation of chromosomal replication so that all origins present are not initiated simultaneously. In this work, several genes whose protein products are involved in initiation of replication have been investigated for their effects on the synchrony of initiation. Some of the mutants (dnaC2, rpoC907, dam3) were found to have the asynchrony phenotype. Also, dnaA(Ts) mutations were shown to be dominant over dnaA+ in terms of initiation synchrony. The mechanism leading to the asynchronous phenotype is discussed.",
keywords = "Bacterial Proteins/genetics, DNA Replication, Escherichia coli/genetics, Flow Cytometry, Genes, Bacterial, Mutation, Phenotype, Plasmids, Time Factors",
author = "E Boye and A L{\o}bner-Olesen and K Skarstad",
year = "1988",
month = dec,
day = "20",
language = "English",
volume = "951",
pages = "359--64",
journal = "Biochimica et Biophysica Acta - Reviews on Cancer",
issn = "0304-419X",
publisher = "Elsevier",
number = "2-3",

}

RIS

TY - JOUR

T1 - Timing of chromosomal replication in Escherichia coli

AU - Boye, E

AU - Løbner-Olesen, A

AU - Skarstad, K

PY - 1988/12/20

Y1 - 1988/12/20

N2 - We have previously shown that certain mutations in the dnaA and recA genes of Escherichia coli perturb initiation of chromosomal replication so that all origins present are not initiated simultaneously. In this work, several genes whose protein products are involved in initiation of replication have been investigated for their effects on the synchrony of initiation. Some of the mutants (dnaC2, rpoC907, dam3) were found to have the asynchrony phenotype. Also, dnaA(Ts) mutations were shown to be dominant over dnaA+ in terms of initiation synchrony. The mechanism leading to the asynchronous phenotype is discussed.

AB - We have previously shown that certain mutations in the dnaA and recA genes of Escherichia coli perturb initiation of chromosomal replication so that all origins present are not initiated simultaneously. In this work, several genes whose protein products are involved in initiation of replication have been investigated for their effects on the synchrony of initiation. Some of the mutants (dnaC2, rpoC907, dam3) were found to have the asynchrony phenotype. Also, dnaA(Ts) mutations were shown to be dominant over dnaA+ in terms of initiation synchrony. The mechanism leading to the asynchronous phenotype is discussed.

KW - Bacterial Proteins/genetics

KW - DNA Replication

KW - Escherichia coli/genetics

KW - Flow Cytometry

KW - Genes, Bacterial

KW - Mutation

KW - Phenotype

KW - Plasmids

KW - Time Factors

M3 - Journal article

C2 - 2850013

VL - 951

SP - 359

EP - 364

JO - Biochimica et Biophysica Acta - Reviews on Cancer

JF - Biochimica et Biophysica Acta - Reviews on Cancer

SN - 0304-419X

IS - 2-3

ER -

ID: 200973468