How skin stem cells engage to maintain tissue function in physiology and disease?
|Målgruppe:||Molecular Biomedicine, Biology, Biochemistry|
Our lab studies the regenerative properties of skin stem cells, and their intercellular connections within their niche in homeostasis and cancer. See https://perezmorenolab.org.
We hope you join our lab and help us discover new molecular aspects of skin stem cell communication.
Our projects are focused on the following aspects:
· Regulation of epidermal progenitor cells self-renewal and differentiation
· Contributions of stromal cells to the skin stem cell niche in homeostasis
· Contributions of stromal cues in cancer stem cell maintenance and tumor progression
We will introduce you to the latest research knowledge in this area.
Our laboratory uses cutting-edge technologies in cell imaging, expression analyses, cell and mouse genetic systems in close collaboration with other leading researchers in the Department and across different national and international institutes.
|Anvendte metoder:||Primary cell cultures, flow cytometry, siRNA/shRNA-mediated gene silencing, cell cycle analysis, cell proliferation and apoptosis assays, immunoblotting, immunoprecipitation, real-time quantitative PCR, gene expression analysis, mutagenesis, bioinformatics analyses, histology, immunofluorescence, immunohistochemistry, confocal microscopy, live cell imaging techniques.|
|Keywords:||stem cells, regeneration, skin, cell biology, cancer|