How skin stem cells engage to maintain tissue function in physiology and disease?

Hovedområde:Cell biology
 
Målgruppe:Molecular Biomedicine, Biology, Biochemistry
 
Niveau:Masters
 
Projektbeskrivelse:

Our lab studies the regenerative properties of skin stem cells, and their intercellular connections within their niche in homeostasis and cancer. See https://perezmorenolab.org.

We hope you join our lab and help us discover new molecular aspects of skin stem cell communication.

Our projects are focused on the following aspects:

·       Regulation of epidermal progenitor cells self-renewal and differentiation

·       Contributions of stromal cells to the skin stem cell niche in homeostasis

·       Contributions of stromal cues in cancer stem cell maintenance and tumor progression

We will introduce you to the latest research knowledge in this area.

Our laboratory uses cutting-edge technologies in cell imaging, expression analyses, cell and mouse genetic systems in close collaboration with other leading researchers in the Department and across different national and international institutes.

 
Anvendte metoder:Primary cell cultures, flow cytometry, siRNA/shRNA-mediated gene silencing, cell cycle analysis, cell proliferation and apoptosis assays, immunoblotting, immunoprecipitation, real-time quantitative PCR, gene expression analysis, mutagenesis, bioinformatics analyses, histology, immunofluorescence, immunohistochemistry, confocal microscopy, live cell imaging techniques.
 
Keywords:stem cells, regeneration, skin, cell biology, cancer
 
Projekthjemmeside: https://perezmorenolab.org
 
Vejleder(e): Mirna Perez-Moreno
 
E-mail:mirna.pmoreno@bio.ku.dk