Project in Population Genetics

Hovedområde:Evolution
 
Målgruppe:Biology
 
Niveau:Bachelor, Outside course scope
 
Projektbeskrivelse:

Population genetics focuses on why and how genetic variation is distributed within and among populations. Changes in allele frequencies in time and space tell us how populations evolve and exchange individuals with other populations, and how the environment influences these processes.

Although the principles of population structure have a theoretical basis that was defined nearly 100 years ago, Population genetic studies use molecular genetic markers based on rad-sequencing, microsatellites, SNPs and DNA sequencing to examine and describe these principles. Bioinformatic analyses use evolutionary and demographic models based on coalescence and MCMC Bayesian statistics to explain diversity and distribution patterns.

In the section for ecology and evolution we use population genetics in studies of epidemics of fungal plant pathogens and to determine the relative importance of clonal and sexual reproduction. In conservation biology, population genetics is used to reveal how populations are structured and to determine gene flow between (sub)populations, allowing the identification of populations at particularly high risk of extinction, and suggesting effective management strategies.

 
Anvendte metoder:molecular genetic markers based on rad-sequencing, microsatellites, SNPs and DNA sequencing, evolutionary and demographic models, MCMC Bayesian statistics
 
Keywords:Genetic diversity, Genetic differentiation, Demography, Population size, Epidemiology
 
Vejleder(e): Søren Rosendahl and/or David Nash
 
E-mail:soerenr@bio.ku.dk