Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor

ORCID: 0000-0002-3044-7714

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  1. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Physiology and pathophysiology of Na+/H+ exchange and Na+-K+-2Cl- cotransport in the heart, brain, and blood

    Pedersen, Stine Helene Falsig, O´Donnell, M. E., Anderson, S. E. & Cala, P. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 1, p. R1-R25

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Physiology of cell volume regulation in vertebrates

    Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: Physiological Reviews. 89, 1, p. 193-277 84 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

    Bødtkjer, E., Bunch, Lennart & Pedersen, Stine Helene Falsig, 2012, In: Current Pharmaceutical Design. 18, 10, p. 1345-1371 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Possible Interrelationship between Changes in F-actin and Myosin II, Protein Phosphorylation and Cell Volume Regulation in Ehrlich Ascites Tumor Cells

    Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2002, In: Experimental Cell Research. 277, p. 57-73

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Profibrotic epithelial phenotype: a central role for MRTF and TAZ

    Bialik, J. F., Ding, M., Speight, P., Dan, Q., Miranda, M. Z., Di Ciano-Oliveira, C., Kofler, M. M., Rotstein, O. D., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2019, In: Scientific Reports. 9, p. 1-14 4323.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Prolactin signaling stimulates invasion via Na+/H+ exchanger NHE1 in T47D human breast cancer cells

    Pedraz Cuesta, E., Fredsted, J., Jensen, H. H., Bornebusch, A., Nejsum, L. N., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2016, In: Molecular Endocrinology. 30, 7, p. 693-708 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Prophylactic effect of citalopram in unipolar, recurrent depression

    Hochstrasser, B., Isaksen, P. M., Koponen, H., Lauritzen, L., Mahnert, F. A., Rouillon, F., Wade, A. G., Andersen, M., Pedersen, Stine Helene Falsig, Swart, J. C. G. D. & Nil, R., 2001, In: British Journal of Psychiatry. 178, p. 304-310

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells

    Andresen, Lars, Hansen, K. A., Jensen, H., Pedersen, Stine Helene Falsig, Stougaard, P., Hansen, H. R., Jurlander, J. & Skov, Søren, 2009, In: Journal of Immunology. 183, 2, p. 897-906 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

    Nadeem, A., Sanborn, J., Gettel, D. L., Ho C.S., J., Rydström, A., Ngassam, V. N., Klausen, T. K., Pedersen, Stine Helene Falsig, Lam, M., Parikh, A. N. & Svanborg, C., 2015, In: Scientific Reports. 5, 14 p., 16432.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer

    Rolver, M. G. & Pedersen, Stine Helene Falsig, 2021, In: British Journal of Cancer. 124, p. 1-2 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  12. Published

    Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1

    Rolver, M. G., Elingaard-Larsen, L. O., Andersen, Anne Poder, Counillon, L. & Pedersen, Stine Helene Falsig, 2020, In: Scientific Reports. 10, 17 p., 5800.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Regulation and roles of bicarbonate transporters in cancer

    Gorbatenko, A., Olesen, C. W., Bødtkjer, E. & Pedersen, Stine Helene Falsig, 2014, In: Frontiers in Physiology. 5, 15 p., 130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Regulation of mitogen-activated protein kinase pathways by the plasma membrane Na+/H+ exchanger, NHE1.

    Pedersen, Stine Helene Falsig, Darborg, B. V., Rentsch, M. L. & Rasmussen, M., 2006, In: Archives of Biochemistry and Biophysics. 462, 2, p. 195-201 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Regulation of the expression and subcellular localization of the taurine transporter TauT in mouse NIH3T3 fibroblasts

    Voss, J. W., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Lambert, Ian Henry, 2004, In: European Journal of Biochemistry. 271, p. 4646-4658

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Response to Schushan et al.: Two conflicting NHE1 model structures: compatibility with experimental data and implications for the transport mechanism

    Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Biological Chemistry. 286, 21, p. le10 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  17. Published

    Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts.

    Pedersen, Stine Helene Falsig, Beisner, K. H., Willumsen, Berthe Marie, Lambert, Ian Henry & Hoffmann, E. K., 2002, In: Journal of Physiology. 541, Pt 3, p. 779-96 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Role of the F-actin cytoskeleton in the RVD and RVI processes in Ehrlich ascites tumor cells.

    Pedersen, Stine Helene Falsig, Mills, J. W. & Hoffmann, E. K., 1999, In: Experimental Cell Research. 252, p. 63-74

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts.

    Rentsch, M. L., Ossum, C. G., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: Pflügers Archiv: European Journal of Physiology. 454, 4, p. 649-62 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Roles of Rho GTPases in the Regulation of Swelling-Activated Osmolyte Efflux in NIH3T3 mouse fibroblasts

    Hougaard, C., Pedersen, Stine Helene Falsig, Jensen, K. H., Lambert, Ian Henry & Hoffmann, E. K., 2001.

    Research output: Contribution to conference › Conference abstract for conference › Research

  21. Published

    Roles of Rho GTPases in the Regulatory Volume Decrease Process in NIH3T3 Mouse Fibroblasts

    Beisner, K. H., Hougaard, C., Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2001.

    Research output: Contribution to conference › Conference abstract for conference › Research

  22. Published

    Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment

    Andersen, Anne Poder, Flinck, M., Oernbo, E. K., Pedersen, N. B., Viuff, B. M. & Pedersen, Stine Helene Falsig, 2016, In: Molecular Cancer. 15, 18 p., 45.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Roles of pH and the Na+/H+ exchanger NHE1 in cancer: from cell biology and animal models to an emerging translational perspective?

    Stock, C. & Pedersen, Stine Helene Falsig, Apr 2017, In: Seminars in Cancer Biology. 43, p. 5-16 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Roles of pH in control of cell proliferation

    Flinck, M., Kramer, S. H. & Pedersen, Stine Helene Falsig, 2018, In: Acta Physiologica. 223, 3, p. 1-17 e13068.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.

    Pedersen, Stine Helene Falsig, Poulsen, K. A. & Lambert, Ian Henry, 2006, In: American Journal of Physiology: Cell Physiology. 291, 6, p. C 1286-1296

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Roles of the cytoskeleton and of Protein Phosphorylation Events in the Osmotic Stress Response in EEL Intestinal Epithelium

    Lionetto, M. G., Pedersen, Stine Helene Falsig, Hoffmann, E. K., Giordano, M. E. & Schettino, T., 2002, In: Cellular Physiology and Biochemistry. 12, 4, p. 163-178 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Sensors and signal transduction in the activation of cell volume regulatory ion transport systems

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 1998, In: Contrib. Nephrol.. 123, p. 50-78

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Sensors and signal transduction pathways in vertebrate cell volume regulation.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: Contributions to Nephrology. 152, p. 54-104 50 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Separate swelling- og Ca2+-activated anion currents in Ehrlich ascites tumor cells

    Pedersen, Stine Helene Falsig, Prenen, J., Droogmans, G., Hoffmann, E. K. & Nilius, B., 1998, In: J. Membrane Biol.. 163, p. 97-110

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: American Journal of Physiology: Cell Physiology. 292, 5, p. C1854-66

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase

    Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  32. Published

    Signal transduction mechanisms involved in the rgulation of NHE1 from Pseudopleuronectes Americanus red blood cells by osmotic shrinkage , ß-adrenergic stimuli, and calyculin A

    Pedersen, Stine Helene Falsig, Holt, M., King, S. A. & Cala, P. M., 2004, In: Bull. Mount Desert Island Biol. Lab. 43, p. 9-11

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Signaling mechanisms regulating the Na+/H+ Exchanger NHE1 in Pleuronectes americanus and Amphiuma tridactylum

    Holt, M. E. V., King, S. A., Rigor, R. R., Cala, P. M. & Pedersen, Stine Helene Falsig, 2003, In: The FASEB Journal. Vol. 19 (4), p. A139-A140

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Snowpack fluxes of methane and carbon dioxide from high Arctic tundra

    Pirk, N., Tamstorf, M. P., Lund, M., Mastepanov, M., Pedersen, Stine Helene Falsig, Mylius, M. R., Parmentier, F. W., Christiansen, H. H. & Christensen, T. R., 2016, In: Journal of Geophysical Research: Biogeosciences. 121, 11, p. 2886-2900 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Spatially resolved analysis of microenvironmental gradient impact on cancer cell phenotypes

    Auxillos, Jamie Yam, Crouigneau, R., Li, Y. F., Dai, Yifan, Stigliani, Arnaud, Tavernaro, I., Resch-Genger, U., Sandelin, Albin Gustav, Marie, R. & Pedersen, Stine Helene Falsig, 2024, In: Science Advances. 10, 18, 17 p., eadn3448.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers

    Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  38. Published

    Structural modeling and electron paramagnetic resonance spectroscopy of the human Na+/H+ exchanger isoform 1, NHE1

    Nygaard, E. B., Lagerstedt, J. O., Bjerre, G., Shi, B., Budamagunta, M., Poulsen, K. A., Lundby, S. M., Rigor, R. R., Voss, J. C., Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: The Journal of Biological Chemistry. 286, 1, p. 634-48 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Swelling-induced arachidonic acid release via the 85-kDa cPLA2 in human neuroblastoma cells

    Basavappa, S., Pedersen, Stine Helene Falsig, Jørgensen, N. K., Ellory, J. C. & Hoffmann, E. K., 1998, In: J. Neurophysiol.. 79, p. 1441-1449

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

    Miranda, M. Z., Bialik, J. F., Speight, P., Dan, Q., Yeung, T., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2017, In: Journal of Biological Chemistry. 292, 36, p. 14902-14920 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    TRP channels: an overview.

    Pedersen, Stine Helene Falsig, Owsianik, G. & Nilius, B., 2005, In: Cell Calcium. 38, 3-4, p. 233-52 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The Acidic Tumor Microenvironment as a Driver of Cancer

    Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2020, In: Annual Review of Physiology. 82, p. 103-126

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer

    Pedersen, Stine Helene Falsig, Flinck, M. & Pardo, L. A., 2021, In: International Journal of Molecular Sciences. 22, 10, 27 p., 5209.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The Na+/H+ Exchange system in Ehrlich ascites tumour cells. Effects of cell volume, phosphorylation and calcium.

    Pedersen, Stine Helene Falsig, Kramhøft, B., Jørgensen, N. K. & Hoffmann, E. K., 1994, In: Acta Physiologica (Print Edition). 151(4), p. 26A

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death.

    Pedersen, Stine Helene Falsig, 2006, In: Pflügers Archiv: European Journal of Physiology. 452, 3, p. 249-59 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium

    Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells.

    Pedersen, Stine Helene Falsig, Rasmussen, M., Darborg, B. V., Nylandsted, J. & Hoffmann, E. K., 2007, In: Cellular Physiology and Biochemistry. 20, 6, p. 735-50 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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