Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor


  1. 2020
  2. Published

    The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

    Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Yeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies

    Kassem, N., Kassem, M. M., Pedersen, Stine Helene Falsig, Pedersen, Per Amstrup & Kragelund, Birthe Brandt, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 14 p., 183272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Why Warburg Works: Lactate Controls Immune Evasion through GPR81

    Jørgensen, Kathrine Lundø, Trauelsen, Mette, Pedersen, Stine Helene Falsig & Schwartz, Thue W., 2020, In: Cell Metabolism. 31, 4, p. 666–668 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  5. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1

    Rolver, M. G., Elingaard-Larsen, L. O., Andersen, Anne Poder, Counillon, L. & Pedersen, Stine Helene Falsig, 2020, In: Scientific Reports. 10, 17 p., 5800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4

    Thiesen, L., Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Helene Falsig, Crocoll, C., Nour-Eldin, Hussam Hassan & Wellendorph, Petrine, 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, p. 1-9 105203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

    Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2019
  10. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer

    Avnet, S., Baldini, N., Brisson, L., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Szabadkai, G. & Pastorekova, S., 2019, In: Frontiers in Oncology. 9, 5 p., 1332.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Profibrotic epithelial phenotype: a central role for MRTF and TAZ

    Bialik, J. F., Ding, M., Speight, P., Dan, Q., Miranda, M. Z., Di Ciano-Oliveira, C., Kofler, M. M., Rotstein, O. D., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2019, In: Scientific Reports. 9, p. 1-14 4323.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    3D multicellular models to study the regulation and roles of acid-base transporters in breast cancer

    Czaplinska, D., Elingaard-Larsen, L. O., Rolver, M. G., Severin, M. & Pedersen, Stine Helene Falsig, 20 Dec 2019, In: Biochemical Society Transactions. 47, 6, p. 1689-1700 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

    Gorbatenko, A., Søkilde, R., Sorensen, E. E., Newie, I., Persson, H., Morancho, B., Arribas, J., Litman, Thomas, Rovira, C. & Pedersen, Stine Helene Falsig, 2019, In: Scientific Reports. 9, 1, p. 1-16 3352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin

    Hendus-Altenburger, R., Wang, X., Sjøgaard-Frich, Lise Margrethe, Pedraz Cuesta, E., Sheftic, S. R., Bendsøe, A. H., Page, R., Kragelund, Birthe Brandt, Pedersen, Stine Helene Falsig & Peti, W., 2019, In: Nature Communications. 10, 13 p., 3489.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Na+/H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration

    Jensen, H. H., Pedersen, G. A., Morgen, J. J., Parsons, M., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2019, In: Journal of Physiology. 597, 3, p. 849-867

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The SLC9A-C Mammalian Na+/H+ Exchanger Family: Molecules, Mechanisms, and Physiology

    Pedersen, Stine Helene Falsig & Counillon, L., 2019, In: Physiological Reviews. 99, 4, p. 2015-2113 99 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

    Rolver, M. G., Elingaard-Larsen, L. O. & Pedersen, Stine Helene Falsig, 2019, In: Journal of Visualized Experiments. 2019, 148, e59714.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

    Tornabene, E., Helms, H. C. C., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2019, In: PLoS ONE. 14, 8, 20 p., e0221103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2018
  20. Published

    The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

    Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Roles of pH in control of cell proliferation

    Flinck, M., Kramer, S. H. & Pedersen, Stine Helene Falsig, 2018, In: Acta Physiologica. 223, 3, p. 1-17 e13068.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells

    Flinck, M., Kramer, S. H., Schnipper, J., Andersen, Anne Poder & Pedersen, Stine Helene Falsig, 2018, In: Cell Cycle. 17, 9, p. 1056-1067

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

    Lee, S., Axelsen, T. V., Jesse, N., Pedersen, Stine Helene Falsig, Vahl, P. & Boedtkjer, E., 2018, In: Oncogene. 37, 41, p. 5569-5584

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Trafficking, localization and degradation of the Na+,HCO3- Co-transporter NBCn1 in kidney and breast epithelial cells

    Olesen, C. W., Vogensen, J., Axholm, I., Severin, M., Schnipper, J., Pedersen, I. S., von Stemann, J. H., Schrøder, J. M., Christensen, D. P. & Pedersen, Stine Helene Falsig, 2018, In: Scientific Reports. 8, p. 1-16 7435.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2017
  26. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer

    Baldini, N., de Milito, A., Feron, O., Gillies, R. J., Michiels, C., Otto, A. M., Pastoreková, S., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Supuran, C. T. & Avnet, S., 4 Jul 2017, In: Frontiers in Pharmacology. 8, 5 p., 411.

    Research output: Contribution to journalComment/debateResearch

  27. Published

    A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)

    Hendus-Altenburger, R., Lambrughi, M., Terkelsen, Thilde Bagger, Pedersen, Stine Helene Falsig, Papaleo, E., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Sep 2017, In: Cellular Signalling. 37, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

    Miranda, M. Z., Bialik, J. F., Speight, P., Dan, Q., Yeung, T., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2017, In: Journal of Biological Chemistry. 292, 36, p. 14902-14920 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer

    Pedersen, A., Mendes Lopes de Melo, J., Mørup, N., Tritsaris, Katerina & Pedersen, Stine Helene Falsig, 2017, In: BMC Cancer. 17, 15 p., 542.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 8742