Søren Tvorup Christensen

Søren Tvorup Christensen

Professor

ORCID: 0000-0001-5004-304X

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  1. Published

    Using quantitative PCR to Identify Kinesin-3 Genes that are Upregulated During Growth Arrest in MouseNIH3T3 Cells

    Thorsteinsson, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 66-86

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  2. Published

    Using quantitative PCR to Identify Kinesin-3 Genes that are Upregulated During Growth Arrest in Mouse NIH3T3 Cells

    Thorsteinsson, R. I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2009, Primary Cilia. Sloboda, R. D. (ed.). Elsevier, p. 66-86 21 p. (Methods in Cell Biology, Vol. 94).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  3. Published

    Using Nucleofection of siRNA Constructs for Knockdown of Primary Cilia in P19.CL6 Cancer Stem Cell Differentiation into Cardiomyocytes

    Clement, C. A., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 181-197

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  4. Published

    Tissue Homeostasis is Regulated by the Primary Cilium in Fibroblasts

    Schneider, L., Pazour, G., Hoffmann, E. K., Satir, P. & Christensen, Søren Tvorup, 2005, In: Molecular Biology of the Cell. Suppl., p. 648 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The primary cilium is a sensory organelle that regulates growth control and tissue homeostasis

    Christensen, Søren Tvorup, Schneider, L., Clement, C. A., Pazour, G., Hoffmann, E. K. & Satir, P., 2006, In: The FASEB Journal. 20, p. A437

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

    Clement, C. A., Kristensen, S. G., Møllgård, Kjeld, Pazour, G. J., Yoder, B. K., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, In: Journal of Cell Science. 122, Pt 17, p. 3070-82 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The primary cilium at a glance

    Satir, P., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2010, In: Journal of Cell Science. 123, Pt 4, p. 499-503 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The lissencephaly protein Lis1 is present in motile mammalian cilia and requires outer arm dynein for targeting to Chlamydomonas flagella.

    Pedersen, Lotte Bang, Rompolas, P., Christensen, Søren Tvorup, Rosenbaum, J. L. & King, S. M., 2007, In: Journal of Cell Science. 120, Pt 5, p. 858-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The intraflagellar transport machinery in ciliary signaling

    Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

    Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The ciliary cytoskeleton

    Pedersen, Lotte Bang, Schrøder, J. M., Satir, P. & Christensen, Søren Tvorup, 2012, In: Comprehensive Physiology. 2, 1, p. 779-803 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium

    Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Tetrahymena cilia - not just oars on a boat

    Guerra, C. F., Christensen, Søren Tvorup, Awan, A., Bell, A., Jabbour, N., Valentin, T. & Satir, P., 2003, In: Molecular Biology of the Cell. vol. 14, p. 434a

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms

    Rosengren, T., Larsen, L. J., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Møller, L. B., 2018, In: Cellular and Molecular Life Sciences. 75, 14, p. 2663-2680 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    TGFβ1-induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner

    Labour, M., Riffault, M., Christensen, Søren Tvorup & Hoey, D. A., 2016, In: Scientific Reports. 6, 13 p., 35542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

    Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Structure and function of mammalian cilia

    Satir, P. & Christensen, Søren Tvorup, 2008, In: Histochemistry and Cell Biology. 129, 6, p. 687-93 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Signalling in cell growth and death: adequate nutrition alone may not be sufficient for ciliates. A minireview

    Wheatley, D. N., Christensen, Søren Tvorup, Schousboe, P. & Rasmussen, L., 1993, In: Cell Biology International. 17, 9, p. 817-23 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Signaling in unicellular eukaryotes

    Christensen, Søren Tvorup, Leick, V. R. & Rasmussen, L., 1997, In: International Review of Cytology. 177, p. 181-253

    Research output: Contribution to journal › Journal article › Research

  23. Published

    Signaling in Tetrahymena Cilia: Evolution of Ciliary Signaling for Mammalian Growth Control Regulation

    Guerra, C. F., Bell, A. J., Awan, A., Christensen, Søren Tvorup & Satir, P., 2005, In: The FASEB Journal. Suppl., p. 652 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Sensory cilia in the female reproductive organs II: Localization of the angiopoetin receptor Tie-2 and the TRP channels PKD2 and OTRPC4

    Teilmann, S. C., Byskov, A. G., Pazour, G. & Christensen, Søren Tvorup, 2003, In: Molecular Biology of the Cell. vol. 14, p. 323a

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Sensory cilia in the female reproductive organs I: Localization of progesterone receptor to cilia of the oviduct

    Teilmann, S. C., Byskov, A. G. & Christensen, Søren Tvorup, 2003, In: Molecular Biology of the Cell. vol. 14, p. 323a

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Sensory cilia and integration of signal transduction in human health and disease.

    Christensen, Søren Tvorup, Pedersen, Lotte Bang, Schneider, L. & Satir, P., 2007, In: Traffic - International Journal of Intracellular Transport. 8, 2, p. 97-109 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Regulation of the expression and subcellular localization of the taurine transporter TauT in mouse NIH3T3 fibroblasts

    Voss, J. W., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Lambert, Ian Henry, 2004, In: European Journal of Biochemistry. 271, p. 4646-4658

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

    Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2018, In: F E B S Journal. 285, 24, p. 4535-4564

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Regulating intraflagellar transport

    Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Nature Cell Biology. 14, 9, p. 904-906 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Receptor tyrosine phosphorylation in cilia: a pathway of growth control?

    Christensen, Søren Tvorup, Schneider, L., Teilmann, S. C., Awan, A., Guerra, C. F., Hoffmann, E. K. & Satir, P., 2004, In: Molecular Biology of the Cell. vol. 15, p. 359a

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

    Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Proteomic analysis of human blastocoel fluid and blastocyst cells

    Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Proteomic analysis of bovine blastocoel fluid and blastocyst cells

    Jensen, P. L., Grøndahl, M. L., Beck, H. C., Petersen, J., Stroebech, L., Christensen, Søren Tvorup & tcg964, tcg964, 2014, In: Systems Biology in Reproductive Medicine. 60, 3, p. 127-135 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Primary cilia as dynamic and diverse signalling hubs in development and disease

    Mill, P., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2023, In: Nature Reviews. Genetics. 24, 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Primary cilia and signaling pathways in mammalian development, health and disease

    Veland, I. R., Awan, A., Pedersen, Lotte Bang, Yoder, B. K. & Christensen, Søren Tvorup, 2009, In: NEPHRON PHYSIOLOGY. 111, 3, p. p39-53

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) signaling

    Christensen, Søren Tvorup, Clement, C. A., Satir, P. & Pedersen, Lotte Bang, 2012, In: Journal of Pathology. 226, 2, p. 172-184 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling

    Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Primary cilia and aberrant cell signaling in epithelial ovarian cancer

    Egeberg, D. L., Lethan, M., Manguso, R., Schneider, L., Awan, A., Jørgensen, T. S., Byskov, A. G., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Cilia. 1, 15, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Porphyrin rings and phospholipids: stimulators of cloning efficiency in certain species of Tetrahymena

    Schousboe, P., Christensen, Søren Tvorup, Ghiladi, M. & Rasmussen, L., 1992, In: Journal of Eukaryotic Microbiology. 39, 2, p. 343-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Physiological studies on the effect of Ca2+ on the duration of the lag phase of Saccharomyces cerevisiae

    Friis, J., Christensen, Søren Tvorup, Szablewski, L., Schousboe, P. & Rasmussen, L., 1994, In: FEMS Microbiology Letters. 123, 1-2, p. 33-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Peter Satir (1936-2022), cell biology pioneer and mentor

    Sale, W. S. & Christensen, Søren Tvorup, 2022, In: Journal of Cell Science. 135, 23

    Research output: Contribution to journal › Comment/debate › Research

  42. Published

    Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia

    Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    PDGFRaa Signaling Is Regulated through the Primary Cilium in Fibroblasts

    Schneider, L., Clement, C. A., Teilmann, S. C., Pazour, G., Hofman, K., Satir, P. & Christensen, Søren Tvorup, 2005, In: Current Biology. 15, 20, p. 1861-1866

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    PDGF-AA Induced Activation of the Mitogenic Erk1/2-Mek1/2 Pathway Localizes to the Primary Cilium and the Ciliary Basal Body in NIH3T3 Fibroblasts

    Clement, C. A., Schneider, L., Teilman, S. C., Satir, P. & Christensen, Søren Tvorup, 2005, In: The FASEB Journal. Suppl., p. 650 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Overview of structure and function of mammalian cilia

    Satir, P. & Christensen, Søren Tvorup, 2007, In: Annual Review of Physiology. 69, p. 377-400 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Origins of signalling and memory: Matters of life versus death

    Wheatley, D. N. & Christensen, Søren Tvorup, 1999, In: Acta Biologica Hungarica. 50(4), p. 441-462

    Research output: Contribution to journal › Journal article › Research

  49. Published

    Non-motile primary cilia in development of unexpected sensory systems

    Satir, P., Guerra, C. F., Schneider, L., Teilmann, S. C., Hoffmann, E. K. & Christensen, Søren Tvorup, 2005, In: The FASEB Journal. Vol. 19 8 (5) Part 2. Suppl., p. A1368-A1369

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    N-acetylcysteine protects ovarian follicles from ischemia-reperfusion injury in xenotransplanted human ovarian tissue

    Olesen, H. Ø., Pors, S. E., Jensen, L. B., Grønning, A. P., Lemser, C. E., Heimbürger, M. T. H. N., Mamsen, L. S., Getreu, N., Christensen, Søren Tvorup, tcg964, tcg964 & Kristensen, S. G., 2021, In: Human Reproduction. 36, 2, p. 429-443 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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