Stine Helene Falsig Pedersen
Professor
Cell Biology and Physiology
Universitetsparken 13
2100 København Ø
- 2024
- Published
Acid–base transporters in the context of tumor heterogeneity
Pedersen, Stine Helene Falsig, 2024, In: Pflugers Archiv European Journal of Physiology. 476, p. 689–701 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells
Meng, Signe, Sørensen, E. E., Ponniah, M., Thorlacius-Ussing, J., Crouigneau, R., Larsen, T., Borre, M. T., Willumsen, N., Flinck, M. & Pedersen, Stine Helene Falsig, 2024, In: Journal of Cell Science. 137, 8, 15 p., jcs261608.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatially resolved analysis of microenvironmental gradient impact on cancer cell phenotypes
Auxillos, Jamie Yam, Crouigneau, R., Li, Y. F., Dai, Yifan, Stigliani, Arnaud, Tavernaro, I., Resch-Genger, U., Sandelin, Albin Gustav, Marie, R. & Pedersen, Stine Helene Falsig, 2024, In: Science Advances. 10, 18, 17 p., eadn3448.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transmembrane transporter proteins: Capturing transport in motion
Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2023
- Published
Aquaporin water channels affect the response of conventional anticancer therapies of 3D grown breast cancer cells
Edamana, S., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2023, In: Biochemical and Biophysical Research Communications. 639, p. 126-133 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic acidosis rewires cancer cell metabolism through PPARα signaling
Rolver, M. G., Holland, L. K. K., Ponniah, M., Prasad, N. S., Yao, Jiayi, Schnipper, J., Kramer, S., Elingaard-Larsen, L., Pedraz-Cuesta, E., Liu, B., Pardo, L. A., Maeda, K., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 8, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness
Czaplinska, D., Ialchina, Renata, Andersen, Henriette Berg, Yao, Jiayi, Stigliani, Arnaud, Dannesboe, Johs, Flinck, M., Chen, X., Mitrega, J., Gnosa, S. P., Dmytriyeva, O., Alves, F., Napp, J., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 6, p. 1210-1225 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia
Severin, M., Pedersen, E. L., Borre, M. T., Axholm, I., Christiansen, F. B., Ponniah, M., Czaplinska, D., Larsen, T., Pardo, L. A. & Pedersen, Stine Helene Falsig, 2023, In: Journal of Cell Science. 136, 7, 20 p., jcs260687.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison
Panou, D. A., Pedersen, Stine Helene Falsig, Kristensen, Mie & Nielsen, Hanne Mørck, 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How protons pave the way to aggressive cancers
Swietach, P., Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2023, In: Nature Reviews Cancer. 23, p. 825-841 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate
Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca2+ Entry and Interaction with PI3K/CaM
Schnipper, J., Kouba, S., Hague, F., Girault, A., Telliez, M., Guenin, S., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: Cancers. 14, 19, 27 p., 4946.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression
Elingaard-Larsen, L. O., Rolver, M. G., Sørensen, E. E. & Pedersen, Stine Helene Falsig, 2022, From Malignant Transformation to Metastasis: Ion Transport in Tumor Biology. Stock, C. & Pardo, L. A. (eds.). Springer, p. 1-38 38 p. (Reviews of Physiology, Biochemistry and Pharmacology, Vol. 182).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase
Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca2+-Independent Manner
Schnipper, J., Kouba, S., Hague, F., Girault, A., Rybarczyk, P., Telliez, M., Guenin, S., Tebbakha, R., Sevestre, H., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: International Journal of Molecular Sciences . 23, 14, 20 p., 7923.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Dynamic Na+/H+ exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca2+-dependent NHE1 activation
Sjøgaard-Frich, Lise Margrethe, Prestel, Andreas, Pedersen, E. S., Severin, M., Kristensen, Kristian Kølby, Olsen, Johan Gotthardt, Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2021, In: eLife. 10, 29 p., e60889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets
Andersen, Henriette Berg, Ialchina, Renata, Pedersen, Stine Helene Falsig & Czaplinska, D., 2021, In: Cancer and Metastasis Reviews. 40, 4, p. 1093-1114 22 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer
Rolver, M. G. & Pedersen, Stine Helene Falsig, 2021, In: British Journal of Cancer. 124, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer
Pedersen, Stine Helene Falsig, Flinck, M. & Pardo, L. A., 2021, In: International Journal of Molecular Sciences. 22, 10, 27 p., 5209.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells
Doray, A., Lemoine, R., Severin, M., Chadet, S., Lopez-Charcas, O., Héraud, A., Baron, C., Besson, P., Monteil, A., Pedersen, Stine Helene Falsig & Roger, S., 2021, In: Cells. 10, 7, 15 p., 1624.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity
Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4
Thiesen, L., Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Helene Falsig, Crocoll, C., Nour-Eldin, Hussam Hassan & Wellendorph, Petrine, 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, p. 1-9 105203.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion
Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival
Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8742
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3550
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Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer
Research output: Contribution to journal › Comment/debate › Research
Published -
2073
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Cell volume regulation in epithelial physiology and cancer
Research output: Contribution to journal › Review › Research › peer-review
Published -
1877
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Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration
Research output: Contribution to journal › Journal article › Research › peer-review
Published