Berthe Marie Willumsen
!!Lektor emerita
Cell Biology and Physiology
Universitetsparken 13
2100 København Ø
- 2018
- Published
Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2
Højfeldt, J. W., Laugesen, A., Willumsen, Berthe Marie, Damhofer, H., Hedehus, L., Tvardovskiy, A., Mohammad, F., Jensen, O. N. & Helin, K., 2018, In: Nature Structural & Molecular Biology. 25, p. 225-232 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation
Mathiasen, D. P., Egebjerg, C., Andersen, S. H., Rafn, B., Puustinen, P., Khanna, A., Daugaard, M., Valo, E., Tuomela, S., Bøttzauw, T., Nielsen, Christian Friberg, Willumsen, Berthe Marie, Hautaniemi, S., Lahesmaa, R., Westermarck, J., Jäättelä, M. & Kallunki, T., 2012, In: Oncogene. 31, p. 390-401 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53
Zandi, R., Selivanova, G., Christensen, C. L., Gerds, Thomas Alexander, Willumsen, Berthe Marie & Poulsen, H. S., 1 May 2011, In: Clinical Cancer Research. 17, 9, p. 2830-2841 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Differential effects of EGFR ligands on endocytic sorting of the receptor
Roepstorff, K., Grandal, M. V., Henriksen, L., Knudsen, S. L. J., Lerdrup, Mads, Grøvdal, L., Willumsen, Berthe Marie & van Deurs, B., 2009, In: Traffic - International Journal of Intracellular Transport. 10, 8, p. 1115-27 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.
Grandal, M. V., Zandi, R., Pedersen, M. W., Willumsen, Berthe Marie, van Deurs, B. & Poulsen, H. S., 2007, In: Carcinogenesis. 28, 7, p. 1408-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Elk3 from hamster--a ternary complex factor with strong transcriptional repressor activity
Hjortø, Gertrud Malene, Weilguny, D. & Willumsen, Berthe Marie, Jan 2005, In: D N A and Cell Biology. 24, 1, p. 35-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-density growth arrest in Ras-transformed cells: low Cdk kinase activities in spite of absence of p27Kip Cdk-complexes
Groth, Anja & Willumsen, Berthe Marie, 2005, In: Cellular Signalling. 17, 9, p. 1063-1073Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution
Hansen, M., Prior, I. A., Hughes, P. E., Oertli, B., Chou, F. L., Willumsen, Berthe Marie, Hancock, J. F. & Ginsberg, M. H., 2003, In: Biochemical and Biophysical Research Communications. 311, p. 829-838Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras
Hansen, M., Rusyn, E. V., Hughes, P. E., Ginsberg, M. H., Cox, A. D. & Willumsen, Berthe Marie, 2002, In: Oncogene. 21, p. 4448-4461Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts.
Pedersen, Stine Helene Falsig, Beisner, K. H., Willumsen, Berthe Marie, Lambert, Ian Henry & Hoffmann, E. K., 2002, In: Journal of Physiology. 541, Pt 3, p. 779-96 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppression of integrin activation by activated Ras or Raf does not correlate with bulk activation of ERK MAP kinase
Hughes, P. E., Oertli, B., Hansen, M., Chou, F. L., Willumsen, Berthe Marie & Ginsberg, M. H., 2002, In: Molecular Biology of the Cell. 13, p. 2256-2265Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements
Nielsen, K. H., Gredsted, L., Broach, J. R. & Willumsen, Berthe Marie, 2001, In: Oncogene. 20, p. 2091-2100Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation
Gjørup, O., Lukas, J., Bartek, J. & Willumsen, Berthe Marie, 1998, In: Journal of Biological Chemistry. 273, p. 18812-18818Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
The Ras-specific exhange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1
Nielsen, K., Papageorge, A. G., Vass, W. C., Willumsen, Berthe Marie & Lowy, D. R., 1997, In: Molecular and Cellular Biology. Vol. 17, p. 7132-7138Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Novel determinants of H-Ras plasma membrane localization and transformation.
Willumsen, Berthe Marie, Cox, A. D., Solski, P. A., Der, C. J. & Buss, J. E., 1996, In: Oncogene. 13, 9, p. 1901-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release.
Leonardsen, L., DeClue, J. E., Lybaek, H., Lowy, D. R. & Willumsen, Berthe Marie, 1996, In: Oncogene. 13, 10, p. 2177-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Analysis of Ras acylation sites: Mutagenesis and Transfection
Willumsen, Berthe Marie, 1995, In Methods in Enzymology, Vol 250. New York: Academic Press, p. 269-284Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Different structural requirements within the switch II region of the RAS protein for interactions with specific downstream targets
Moodie, S. A., Paris, M., Villafranca, E., Kirchmeier, P., Willumsen, Berthe Marie & Wolfman, A., 1995, In: Oncogene. 11, p. 447-454Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of Expression of inducible ß-Galactosidase in murine Fibroblasts: High initial rate compared to steady state expression
Jacobsen, K. & Willumsen, Berthe Marie, 1995, In: Journal of Molecular Biology. 252, p. 289-295Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational cancer therapy
Lowy, D. R. & Willumsen, Berthe Marie, 1995, In: Nature Medicine. Vol 1, No 8, p. 747-748Research output: Contribution to journal › Letter › Research
- Published
Two distinct regions of Ras participate in functional interaction with GDP-GTP exchangers
Segal, M., Marbach, I., Willumsen, Berthe Marie & Levitzki, A., 1995, In: FEBS Journal. 228, p. 96-101Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Complexes of Ras GTP with Raf-1 and nitrogen-activated protein kinase kinase
Moodie, S. A., Willumsen, Berthe Marie, Weber, M. J. & Wolfman, A., 1993, In: Kexue (Shanghai). Vol. 260, p. 1658-1661Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Function and regulation of Ras
Lowy, D. R. & Willumsen, Berthe Marie, 1993, In: Annual Review of Biochemistry. Vol. 62, p. 851-891Research output: Contribution to journal › Review › Research
- Published
Residues crucial for Ras interaction with GDP-GTP exchangers
Segal, M., Willumsen, Berthe Marie & Levitzki, A., 1993, In: Proceedings of the National Academy of Science of the United States of America. 90, p. 5564-5568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ras transforming protein
Willumsen, Berthe Marie, 1993, Copenhagen: Academic Press. 124 p.Research output: Book/Report › Doctoral thesis › Research
- 1992
- Published
Regulation of p21ras activity.
Lowy, D. R., Zhang, K., DeClue, J. E. & Willumsen, Berthe Marie, 1992, In: Trends in Genetics. 7, 11-12, p. 346-51 5 p.Research output: Contribution to journal › Review › Research
- 1991
- Published
Inhibition of Cell Growth by Lovastatin Is Independent of ras Function
DeClue, J. E., Vass, W. C., Papageorge, A. G., Lowy, D. R. & Willumsen, Berthe Marie, 1991, In: Cancer Research. 51, p. 712-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.
Willumsen, Berthe Marie, Vass, W. C., Velu, T. J., Papageorge, A. G., Schiller, J. T. & Lowy, D. R., 1991, In: Molecular and Cellular Biology. 11, 12, p. 6026-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1989
- Published
Protein modification: new clue to Ras lipid glue.
Lowy, D. R. & Willumsen, Berthe Marie, 1989, In: Nature. 341, 6241, p. 384-5 1 p.Research output: Contribution to journal › Letter › Research
- 1988
- Published
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain.
Adari, H., Lowy, D. R., Willumsen, Berthe Marie, Der, C. J. & McCormick, F., 1988, In: Science. 240, 4851, p. 518-21 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
p21-ras effector domain mutants constructed by "cassette" mutagenesis.
Stone, J. C., Vass, W. C., Willumsen, Berthe Marie & Lowy, D. R., 1988, In: Molecular and Cellular Biology. 8, 8, p. 3565-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1986
- Published
A transforming ras gene can provide an essential function ordinarily supplied by an endogenous ras gene.
Papageorge, A. G., Willumsen, Berthe Marie, Johnsen, M., Kung, H. F., Stacey, D. W., Vass, W. C. & Lowy, D. R., 1986, In: Molecular and Cellular Biology. 6, 5, p. 1843-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational analysis of a ras catalytic domain.
Willumsen, Berthe Marie, Papageorge, A. G., Kung, H. F., Bekesi, E., Robins, T., Johnsen, M., Vass, W. C. & Lowy, D. R., 1986, In: Molecular and Cellular Biology. 6, 7, p. 2646-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1985
- Published
Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.
Willumsen, Berthe Marie, Papageorge, A. G., Hubbert, N., Bekesi, E., Kung, H. F. & Lowy, D. R., 1985, In: EMBO Journal. 4, 11, p. 2893-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1984
- Published
Further genetic localization of the transforming sequences of the p21 v-ras gene of Harvey murine sarcoma virus.
Willumsen, Berthe Marie, Ellis, R. W., Willumsen, Berthe Marie & Lowy, D. R., 1984, In: Journal of Virology. 49, 2, p. 601-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.
Willumsen, Berthe Marie, Norris, K., Papageorge, A. G., Hubbert, N. L. & Lowy, D. R., 1984, In: EMBO Journal. 3, 11, p. 2581-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The p21 ras C-terminus is required for transformation and membrane association.
Willumsen, Berthe Marie, Christensen, A., Hubbert, N. L., Papageorge, A. G. & Lowy, D. R., 1984, In: Nature. 310, 5978, p. 583-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1979
- Published
In vitro selection of high-infectious, leukemogenic virus from low-infectious, non-leukemogenic type C virus from a malignant ST/a mouse cell line.
Willumsen, Berthe Marie, 1979, In: Journal of Virology. 29, 3, p. 1213-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serological identification of neoantigens on mouse fibroblasts which have undergone "spontaneous" malignant alteration in vitro.
Willumsen, Berthe Marie, Ulrich, K. & Kieler, J., 1979, In: International Journal of Cancer. 23, 2, p. 209-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1977
- Published
Interaction of alleles of the relA, relC and spoT genes in Escherichia coli: analysis of the interconversion of GTP, ppGpp and pppGpp.
Fiil, N. P., Willumsen, Berthe Marie, Friesen, J. D. & von Meyenburg, K., 1977, In: Molecular Genetics and Genomics. 150, 1, p. 87-101 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9713