Berthe Marie Willumsen

Berthe Marie Willumsen

!!Lektor emerita


  1. 2018
  2. Published

    Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

    Højfeldt, J. W., Laugesen, A., Willumsen, Berthe Marie, Damhofer, H., Hedehus, L., Tvardovskiy, A., Mohammad, F., Jensen, O. N. & Helin, K., 2018, In: Nature Structural & Molecular Biology. 25, p. 225-232 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2012
  4. Published

    Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

    Mathiasen, D. P., Egebjerg, C., Andersen, S. H., Rafn, B., Puustinen, P., Khanna, A., Daugaard, M., Valo, E., Tuomela, S., Bøttzauw, T., Nielsen, Christian Friberg, Willumsen, Berthe Marie, Hautaniemi, S., Lahesmaa, R., Westermarck, J., Jäättelä, M. & Kallunki, T., 2012, In: Oncogene. 31, p. 390-401 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2011
  6. Published

    PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53

    Zandi, R., Selivanova, G., Christensen, C. L., Gerds, Thomas Alexander, Willumsen, Berthe Marie & Poulsen, H. S., 1 May 2011, In: Clinical Cancer Research. 17, 9, p. 2830-2841 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2009
  8. Published

    Differential effects of EGFR ligands on endocytic sorting of the receptor

    Roepstorff, K., Grandal, M. V., Henriksen, L., Knudsen, S. L. J., Lerdrup, Mads, Grøvdal, L., Willumsen, Berthe Marie & van Deurs, B., 2009, In: Traffic - International Journal of Intracellular Transport. 10, 8, p. 1115-27 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2007
  10. Published

    EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.

    Grandal, M. V., Zandi, R., Pedersen, M. W., Willumsen, Berthe Marie, van Deurs, B. & Poulsen, H. S., 2007, In: Carcinogenesis. 28, 7, p. 1408-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2005
  12. Published

    Elk3 from hamster--a ternary complex factor with strong transcriptional repressor activity

    Hjortø, Gertrud Malene, Weilguny, D. & Willumsen, Berthe Marie, Jan 2005, In: D N A and Cell Biology. 24, 1, p. 35-42 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    High-density growth arrest in Ras-transformed cells: low Cdk kinase activities in spite of absence of p27Kip Cdk-complexes

    Groth, Anja & Willumsen, Berthe Marie, 2005, In: Cellular Signalling. 17, 9, p. 1063-1073

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2003
  15. Published

    C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution

    Hansen, M., Prior, I. A., Hughes, P. E., Oertli, B., Chou, F. L., Willumsen, Berthe Marie, Hancock, J. F. & Ginsberg, M. H., 2003, In: Biochemical and Biophysical Research Communications. 311, p. 829-838

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2002
  17. Published

    R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras

    Hansen, M., Rusyn, E. V., Hughes, P. E., Ginsberg, M. H., Cox, A. D. & Willumsen, Berthe Marie, 2002, In: Oncogene. 21, p. 4448-4461

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts.

    Pedersen, Stine Helene Falsig, Beisner, K. H., Willumsen, Berthe Marie, Lambert, Ian Henry & Hoffmann, E. K., 2002, In: Journal of Physiology. 541, Pt 3, p. 779-96 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Suppression of integrin activation by activated Ras or Raf does not correlate with bulk activation of ERK MAP kinase

    Hughes, P. E., Oertli, B., Hansen, M., Chou, F. L., Willumsen, Berthe Marie & Ginsberg, M. H., 2002, In: Molecular Biology of the Cell. 13, p. 2256-2265

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2001
  21. Published

    Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements

    Nielsen, K. H., Gredsted, L., Broach, J. R. & Willumsen, Berthe Marie, 2001, In: Oncogene. 20, p. 2091-2100

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 1998
  23. Published

    Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation

    Gjørup, O., Lukas, J., Bartek, J. & Willumsen, Berthe Marie, 1998, In: Journal of Biological Chemistry. 273, p. 18812-18818

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 1997
  25. Published

    The Ras-specific exhange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1

    Nielsen, K., Papageorge, A. G., Vass, W. C., Willumsen, Berthe Marie & Lowy, D. R., 1997, In: Molecular and Cellular Biology. Vol. 17, p. 7132-7138

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 1996
  27. Published

    Novel determinants of H-Ras plasma membrane localization and transformation.

    Willumsen, Berthe Marie, Cox, A. D., Solski, P. A., Der, C. J. & Buss, J. E., 1996, In: Oncogene. 13, 9, p. 1901-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release.

    Leonardsen, L., DeClue, J. E., Lybaek, H., Lowy, D. R. & Willumsen, Berthe Marie, 1996, In: Oncogene. 13, 10, p. 2177-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 1995
  30. Published

    Analysis of Ras acylation sites: Mutagenesis and Transfection

    Willumsen, Berthe Marie, 1995, In Methods in Enzymology, Vol 250. New York: Academic Press, p. 269-284

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  31. Published

    Different structural requirements within the switch II region of the RAS protein for interactions with specific downstream targets

    Moodie, S. A., Paris, M., Villafranca, E., Kirchmeier, P., Willumsen, Berthe Marie & Wolfman, A., 1995, In: Oncogene. 11, p. 447-454

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Kinetics of Expression of inducible ß-Galactosidase in murine Fibroblasts: High initial rate compared to steady state expression

    Jacobsen, K. & Willumsen, Berthe Marie, 1995, In: Journal of Molecular Biology. 252, p. 289-295

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Rational cancer therapy

    Lowy, D. R. & Willumsen, Berthe Marie, 1995, In: Nature Medicine. Vol 1, No 8, p. 747-748

    Research output: Contribution to journalLetterResearch

  34. Published

    Two distinct regions of Ras participate in functional interaction with GDP-GTP exchangers

    Segal, M., Marbach, I., Willumsen, Berthe Marie & Levitzki, A., 1995, In: FEBS Journal. 228, p. 96-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 1993
  36. Published

    Complexes of Ras GTP with Raf-1 and nitrogen-activated protein kinase kinase

    Moodie, S. A., Willumsen, Berthe Marie, Weber, M. J. & Wolfman, A., 1993, In: Kexue (Shanghai). Vol. 260, p. 1658-1661

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Function and regulation of Ras

    Lowy, D. R. & Willumsen, Berthe Marie, 1993, In: Annual Review of Biochemistry. Vol. 62, p. 851-891

    Research output: Contribution to journalReviewResearch

  38. Published

    Residues crucial for Ras interaction with GDP-GTP exchangers

    Segal, M., Willumsen, Berthe Marie & Levitzki, A., 1993, In: Proceedings of the National Academy of Science of the United States of America. 90, p. 5564-5568

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Ras transforming protein

    Willumsen, Berthe Marie, 1993, Copenhagen: Academic Press. 124 p.

    Research output: Book/ReportDoctoral thesisResearch

  40. 1992
  41. Published

    Regulation of p21ras activity.

    Lowy, D. R., Zhang, K., DeClue, J. E. & Willumsen, Berthe Marie, 1992, In: Trends in Genetics. 7, 11-12, p. 346-51 5 p.

    Research output: Contribution to journalReviewResearch

  42. 1991
  43. Published

    Inhibition of Cell Growth by Lovastatin Is Independent of ras Function

    DeClue, J. E., Vass, W. C., Papageorge, A. G., Lowy, D. R. & Willumsen, Berthe Marie, 1991, In: Cancer Research. 51, p. 712-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.

    Willumsen, Berthe Marie, Vass, W. C., Velu, T. J., Papageorge, A. G., Schiller, J. T. & Lowy, D. R., 1991, In: Molecular and Cellular Biology. 11, 12, p. 6026-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 1989
  46. Published

    Protein modification: new clue to Ras lipid glue.

    Lowy, D. R. & Willumsen, Berthe Marie, 1989, In: Nature. 341, 6241, p. 384-5 1 p.

    Research output: Contribution to journalLetterResearch

  47. 1988
  48. Published

    Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain.

    Adari, H., Lowy, D. R., Willumsen, Berthe Marie, Der, C. J. & McCormick, F., 1988, In: Science. 240, 4851, p. 518-21 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    p21-ras effector domain mutants constructed by "cassette" mutagenesis.

    Stone, J. C., Vass, W. C., Willumsen, Berthe Marie & Lowy, D. R., 1988, In: Molecular and Cellular Biology. 8, 8, p. 3565-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 1986
  51. Published

    A transforming ras gene can provide an essential function ordinarily supplied by an endogenous ras gene.

    Papageorge, A. G., Willumsen, Berthe Marie, Johnsen, M., Kung, H. F., Stacey, D. W., Vass, W. C. & Lowy, D. R., 1986, In: Molecular and Cellular Biology. 6, 5, p. 1843-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Mutational analysis of a ras catalytic domain.

    Willumsen, Berthe Marie, Papageorge, A. G., Kung, H. F., Bekesi, E., Robins, T., Johnsen, M., Vass, W. C. & Lowy, D. R., 1986, In: Molecular and Cellular Biology. 6, 7, p. 2646-54 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 1985
  54. Published

    Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.

    Willumsen, Berthe Marie, Papageorge, A. G., Hubbert, N., Bekesi, E., Kung, H. F. & Lowy, D. R., 1985, In: EMBO Journal. 4, 11, p. 2893-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 1984
  56. Published

    Further genetic localization of the transforming sequences of the p21 v-ras gene of Harvey murine sarcoma virus.

    Willumsen, Berthe Marie, Ellis, R. W., Willumsen, Berthe Marie & Lowy, D. R., 1984, In: Journal of Virology. 49, 2, p. 601-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

    Willumsen, Berthe Marie, Norris, K., Papageorge, A. G., Hubbert, N. L. & Lowy, D. R., 1984, In: EMBO Journal. 3, 11, p. 2581-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The p21 ras C-terminus is required for transformation and membrane association.

    Willumsen, Berthe Marie, Christensen, A., Hubbert, N. L., Papageorge, A. G. & Lowy, D. R., 1984, In: Nature. 310, 5978, p. 583-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 1979
  60. Published

    In vitro selection of high-infectious, leukemogenic virus from low-infectious, non-leukemogenic type C virus from a malignant ST/a mouse cell line.

    Willumsen, Berthe Marie, 1979, In: Journal of Virology. 29, 3, p. 1213-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Serological identification of neoantigens on mouse fibroblasts which have undergone "spontaneous" malignant alteration in vitro.

    Willumsen, Berthe Marie, Ulrich, K. & Kieler, J., 1979, In: International Journal of Cancer. 23, 2, p. 209-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. 1977
  63. Published

    Interaction of alleles of the relA, relC and spoT genes in Escherichia coli: analysis of the interconversion of GTP, ppGpp and pppGpp.

    Fiil, N. P., Willumsen, Berthe Marie, Friesen, J. D. & von Meyenburg, K., 1977, In: Molecular Genetics and Genomics. 150, 1, p. 87-101 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 9713