Henriette Pilegaard

Henriette Pilegaard

Professor

ORCID: 0000-0002-1071-0327

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  1. Published

    Menopause is associated with decreased whole body fat oxidation during exercise

    Abildgaard, J., Pedersen, Anette Tønnes, Green, C. J., Majlund Harder-Lauridsen, N., Solomon, T. P., Thomsen, C., Juul, A., Pedersen, M., Pedersen, J. T., Mortensen, Ole Hartvig, Pilegaard, Henriette, Pedersen, Bente Klarlund & Lindegaard, B., 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 11, p. E1227-E1236 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle

    Adhihetty, P. J., Uguccioni, G., Leick, L., Hidalgo, J., Pilegaard, Henriette & Hood, D. A., 2009, In: American Journal of Physiology: Cell Physiology. 297, 1, p. C217-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown and increased IL-6 release

    Bach, E., Nielsen, R. R., Vendelbo, M., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, Henriette, Biensøe, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Diabetes. 62, 12, p. 4023-4029

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Impact of skeletal muscle IL-6 on subcutaneous and visceral adipose tissue metabolism immediately after high- and moderate-intensity exercises

    Bertholdt, L., Gudiksen, Anders, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 217-233 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lack of skeletal muscle IL-6 influences hepatic glucose metabolism in mice during prolonged exercise

    Bertholdt, L., Gudiksen, Anders, Schwartz, C. L., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 7 Apr 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 4, p. R626-R636 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Bed Rest-Induced Changes in TBC1D4 Phosphorylation and Glycogen Synthase Activity. Effects of Acute Exercise

    Bienso, R. S., Ringholm, S., Lundby, C., Achman-Andersen, N. J., Plomgaard, Peter Stendahl, Krogh-Madsen, Rikke, Kiilerich, K., Guerra, B., Treebak, Jonas Thue, Calbet, J. A., Pilegaard, Henriette & Wojtaszewski, J. J. F., 2010, In: Diabetes.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Exercise-induced AMPK and pyruvate dehydrogenase regulation is maintained during short-term low-grade inflammation

    Biensø, R. S., Olesen, J., van Hauen, L., Meinertz, S., Halling, J. F., Gliemann, Lasse, Plomgaard, P. & Pilegaard, Henriette, 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 2, p. 341-350 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes 2012;61:1090-1099

    Biensø, R. S., Ringholm, S., Kiilerich, K., Aachmann-Andersen, N., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2014, In: Diabetes. 63, 9, 1 p., 3159.

    Research output: Contribution to journal › Comment/debate › Research

  11. Published

    Effects of IL-6 on pyruvate dehydrogenase regulation in mouse skeletal muscle

    Biensø, R. S., Knudsen, Jakob Grunnet, Brandt, N., Pedersen, Per Amstrup & Pilegaard, Henriette, 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 8, p. 1647-1657 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance

    Biensø, R. S., Jørgensen, Stine Ringholm, Kiilerich, K., Aachmann-Andersen, N. J., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2012, In: Diabetes. 61, 5, p. 1090-1099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effects of exercise training on regulation of skeletal muscle glucose metabolism in elderly men

    Biensø, R. S., Olesen, J., Gliemann, Lasse, Schmidt, J. F., Matzen, M. S., Wojtaszewski, Jørgen F P, Hellsten, Ylva & Pilegaard, Henriette, 2015, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 70, 7, p. 866-872 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle

    Brandauer, J., Vienberg, S. G., Andersen, M. A., Jørgensen, Stine Ringholm, Risis, S., Larsen, P., Kristensen, Jonas Møller, Frøsig, C., Leick, L., Fentz, J., Jørgensen, S. B., Kiens, Bente, Wojtaszewski, Jørgen F P, Richter, Erik A., Zierath, Juleen R, Goodyear, L. J., Pilegaard, Henriette & Treebak, Jonas Thue, 2013, In: Journal of Physiology. 591, p. 5207-5220 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    IL-6 regulates exercise and training-induced adaptations in subcutaneous adipose tissue in mice

    Brandt, C., Jakobsen, A. H., Hassing, H. A., Olesen, Jes, Iversen, N., Kristensen, Jonas Møller, Hojman, P., Wojtaszewski, Jørgen F P, Hidalgo, J. & Pilegaard, Henriette, 2012, In: Acta Physiologica (Print). 205, 2, p. 224-235 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Impact of adrenaline and metabolic stress on exercise-induced intracellular signaling and PGC-1α mRNA response in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Hostrup, Morten, Tybirk, J., Nybo, Lars, Pilegaard, Henriette & Bangsbo, Jens, 2016, In: Physiological Reports. 4, 14, 13 p., e12844.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle

    Brandt, N., Dethlefsen, M. M., Bangsbo, Jens & Pilegaard, Henriette, 2017, In: P L o S One. 12, 10, 21 p., e0185993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    LIF is a contraction-induced myokine stimulating human myocyte proliferation

    Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, Henriette, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2011, In: Journal of Applied Physiology. 111, 1, p. 251-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner

    Buch, B. T., Halling, Jens Frey, Jørgensen, Stine Ringholm, Gudiksen, Anders, Kjøbsted, Rasmus, Olsen, M. A., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2020, In: F A S E B Journal. 34, 6, p. 8653-8670

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg

    Buhl, M., Bosnjak, E., Vendelbo, M. H., Gjedsted, J., Nielsen, R. R., Hafstrøm, T. K., Vestergaard, E. T., Jessen, N., Tønnesen, E., Møller, A. B., Pedersen, S. B., Pilegaard, Henriette, Biensø, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 5, p. 2090-2099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion

    Carey, A., Wolsk, E., Bruce, C., Southgate, R., Pilegaard, Henriette, Hawley, J. A., Pedersen, B. K. & Febrario, M., 2006, In: Diabetologia. 49, 5, p. 1000-1007

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects

    Christensen, B., Lundby, C., Jessen, N., Nielsen, Thomas Svava, Vestergaard, P. F., Møller, N., Pilegaard, Henriette, Pedersen, S. B., Kopchick, J. J. & Jørgensen, J. O. L., 2012, In: P L o S One. 7, 2, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Muscle PGC-1α modulates hepatic mitophagy regulation during aging

    Christensen, N. M., Jørgensen, Stine Ringholm, Buch, B. T., Gudiksen, Anders, Halling, Jens Frey & Pilegaard, Henriette, 2023, In: Experimental Gerontology. 172, 9 p., 112046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle

    Coffey, V. G., Pilegaard, Henriette, Garnham, A. P., O'Brien, B. J. & Hawley, J. A., 2009, In: Journal of Applied Physiology. 106, 4, p. 1187-97 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock

    Dyar, K. A., Ciciliot, S., Wright, L. E., Biensø, R. S., Tagliazucchi, G. M., Patel, V. R., Forcato, M., Paz, M. I. P., Gudiksen, Anders, Solagna, F., Albiero, M., Moretti, I., Eckel-Mahan, K. L., Baldi, P., Sassone-Corsi, P., Rizzuto, R., Bicciato, S., Pilegaard, Henriette, Blaauw, B. & Schiaffino, S., 2014, In: Molecular Metabolism. 3, 1, p. 29-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle

    Edge, J., Muendel, T., Pilegaard, Henriette, Hawke, E., Leikis, M., Lopez-Villalobos, N., Oliveira, R. S. F. & Bishop, D. J., 2015, In: P L o S One. 10, 12, 14 p., e0141317.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9

    Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle

    Fentz, J., Kjøbsted, Rasmus, Maag Kristensen, C., Hingst, J. R., Birk, Jesper Bratz, Gudiksen, Anders, Foretz, M., Schjerling, Peter, Viollet, B., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 309, 11, p. E900-E914 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle

    Fischer, C. P., Plomgaard, P., Hansen, A. K., Pilegaard, Henriette, Saltin, B. & Pedersen, B. K., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, p. E-1189-E1194

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    5´AMP activated protein kinase α2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jeppesen, J., Christiansen, M. L. B., Biensø, R. S., Dyck, J. R. B., Pilegaard, Henriette & Kiens, Bente, 2015, In: Journal of Physiology. 593, 21, p. 4765-4780 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    New Nordic Diet induced weight loss is accompanied by changes in metabolism and AMPK signalling in adipose tissue

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jordy, A. B., Poulsen, S. K., Stender, Steen, Pilegaard, Henriette, Astrup, A., Larsen, T. M., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 9, p. 3509-3519 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Reply from Lasse Gliemann, Jesper Olesen, Rasmus Sjørup Biensø, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Olesen, J., Biensø, R. S., Mortensen, S. P., Nyberg, M. P., Schmidt, J. F., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 3, p. 553 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  40. Published

    Reply from Lasse Gliemann, Jakob Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Schmidt, J., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5253 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  41. Published

    Effects of training status on PDH regulation in human skeletal muscle during exercise

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Tybirk, J., Plomgaard, Peter Stendahl, Bangsbo, Jens & Pilegaard, Henriette, 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 12, p. 1615-1630 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue

    Gudiksen, Anders, Qoqaj, A., Jørgensen, Stine Ringholm, Wojtaszewski, Jørgen F P, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2022, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 77, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Lack of skeletal muscle IL-6 affects pyruvate dehydrogenase activity at rest and during prolonged exercise

    Gudiksen, Anders, Schwartz, C. L., Bertholdt, L., Joensen, E., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 2016, In: P L o S One. 11, 6, 17 p., e0156460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders & Pilegaard, Henriette, 10 Apr 2017, In: Physiological Reports. 5, 7, 15 p., e13222.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Vingborg, M. B., Hansen, H. W., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E204-E214 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Leptin signaling in skeletal muscle after bed rest in healthy humans

    Guerra, B., Ponce-Gonzalez, J. G., Morales-Alamo, D., Guadalupe-Grau, A., Kiilerich, K., Fuentes, T., Jørgensen, Stine Ringholm, Biensø, R. S., Santana, A., Lundby, C., Pilegaard, Henriette & Calbet, J. A. L., 2014, In: European Journal of Applied Physiology. 114, 2, p. 345-357 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Inclusion of sprints in moderate intensity continuous training leads to muscle oxidative adaptations in trained individuals

    Gunnarsson, T. G. P., Brandt, N., Fiorenza, Matteo, Hostrup, Morten, Pilegaard, Henriette & Bangsbo, Jens, 2019, In: Physiological Reports. 7, 4, 15 p., e13976.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Role of PGC-1{alpha} in exercise and fasting induced adaptations in mouse liver

    Haase, T. N., Jørgensen, S. R., Leick, L., Biensø, R. S., Kiilerich, K., Johansen, S., Nielsen, M. M., Wojtaszewski, Jørgen F P, Hidalgo, J., Pedersen, Per Amstrup & Pilegaard, Henriette, 2011, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 301, 5, p. R1501-R1509 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Nielsen, M. M., Overby, P. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 3, 11 p., e12698.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training

    Halling, Jens Frey, Jessen, H., Nøhr-Meldgaard, J., Buch, B. T., Christensen, N. M., Gudiksen, Anders, Jørgensen, Stine Ringholm, Neufer, P. D., Prats Gavalda, Clara & Pilegaard, Henriette, 2019, In: American journal of physiology. Endocrinology and metabolism. 317, 3, p. E513-E525

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    PGC-1α-mediated regulation of mitochondrial function and physiological implications

    Halling, Jens Frey & Pilegaard, Henriette, 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Olesen, J., Prats Gavalda, Clara & Pilegaard, Henriette, 1 Oct 2017, In: Experimental Gerontology. 96, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Autophagy-dependent beneficial effects of exercise

    Halling, Jens Frey & Pilegaard, Henriette, Aug 2017, In: Cold Spring Harbor Perspectives in Medicine. 7, 8, a029777.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Exercise physiology: future opportunities and challenges

    Han, J., Neufer, D. & Pilegaard, Henriette, 2019, In: Pflügers Archiv - European Journal of Physiology. 471, 3, p. 381 1 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  56. Published

    Exercise: from physiology to bedside to physiology

    Han, J., Neufer, D. & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 135

    Research output: Contribution to journal › Editorial › Research › peer-review

  57. Published

    High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells

    Hansen, Camilla Collin, Olsen, K., Pilegaard, Henriette, Bangsbo, Jens, Gliemann, Lasse & Hellsten, Ylva, 2021, In: Physiological Reports. 9, 14, 17 p., e14855.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Interleukin-6 modifies mRNA expression in mouse skeletal muscle

    Hassing, H. A., Wojtaszewski, Jørgen F P, Jakobsen, A. H., Kiilerich, K., Hidalgo, J. & Pilegaard, Henriette, 2011, In: Acta Physiologica. 202, 2, p. 165-173 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Increased fat oxidation and regulation of metabolic genes with ultraendurance exercise

    Helge, J. W., Rehrer, N. J., Pilegaard, Henriette, Manning, P., Lucas, S. J. E., Gerrard, D. F. & Cotter, J. D., 2007, In: Acta Physiologica (Print Edition). 191, 1, p. 77-86 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscle

    Hellsten, Ylva, Nielsen, Jens Jung, Lykkesfeldt, J., Bruhn, M., Silveira, L., Pilegaard, Henriette & Bangsbo, Jens, 2007, In: Free Radical Biology & Medicine. 43, 3, p. 353-361 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Transgenic mice with astrocyte-targeted production of interleukin-6 are resistant to high-fat diet-induced increases in body weight and body fat

    Hidalgo, J., Florit, S., Giralt, M., Ferrer, B., Keller, C. & Pilegaard, Henriette, 2010, In: Brain, Behavior, and Immunity. 24, 1, p. 119-26 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Vascular endothelial growth factor mRNA expression and arteriovenous balance in resonse to prolonged, submaximal exercise in humans

    Hiscock, N., Fischer, C. P., Pilegaard, Henriette & Pedersen, B. K., 2003, In: Am J Physiol - Heart Circ Physiol. 285, p. H1759-H1763

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2x2 factorial, randomised, crossover study in human individuals

    Hjelholt, A. J., Charidemou, E., Griffin, J. L., Pedersen, S. B., Gudiksen, Anders, Pilegaard, Henriette, Jessen, N., Møller, N. & Jørgensen, J. O. L., 2020, In: Diabetologia. 63, 12, p. 2641-2653 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Beta2-adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men

    Hostrup, Morten, Reitelseder, S., Jessen, Søren Kaare, Kalsen, A., Nyberg, M. P., Egelund, J., Kreiberg, M., Maag Kristensen, C., Thomassen, Martin, Pilegaard, Henriette, Backer, Vibeke, Jacobson, G. A., Holm, L. & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 17, p. 4121-4139 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Beta2-agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men

    Hostrup, Morten, Knudsen, Jakob Grunnet, Maag Kristensen, C., Jessen, Søren Kaare, Pilegaard, Henriette & Bangsbo, Jens, 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 7, p. 1099-1108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

    Gliemann, Lasse, Schmidt, J. F., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M. P., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5047-5059 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Lipid induced insulin resistance affects women less than men and is not accompanied by inflammation or impaired proximal insulin signaling

    Høeg, L. D., Sjøberg, K. A., Jeppesen, J., Jensen, Thomas Elbenhardt, Frøsig, C., Birk, Jesper Bratz, Bisiani, B., Hiscock, N., Pilegaard, Henriette, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2011, In: Diabetes. 60, 1, p. 64-73 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

    Høgild, M. L., Gudiksen, Anders, Pilegaard, Henriette, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jørgensen, J. O. L. & Jessen, N., 2019, In: Physiological Reports. 7, 21, 15 p., e14285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle

    Høier, B., Prats Gavalda, Clara, Qvortrup, Klaus, Pilegaard, Henriette, Bangsbo, Jens & Hellsten, Ylva, 2013, In: F A S E B Journal. 27, 9, p. 3496-3504 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Na,K-ATPase activity in mouse muscle is regulated by AMPK and PGC-1a

    Ingwersen, M. S., Kristensen, M., Pilegaard, Henriette, Wojtaszewski, Jørgen F P, Richter, Erik A. & Juel, C., 2011, In: Journal of Membrane Biology. 242, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Mitochondrial biogenesis and angiogenesis in skeletal muscle of the elderly

    Iversen, N., Krustrup, P., Rasmussen, H. N., Feldt-Rasmussen, Ulla, Saltin, B. & Pilegaard, Henriette, 2011, In: Experimental Gerontology. 46, 8, p. 670-678 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Effect of acute exercise and exercise training on VEGF splice variants in human skeletal muscle

    Jensen, L., Pilegaard, Henriette, Neufer, P. D. & Hellsten, Ylva, 2004, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 287, 2, p. R397-R402 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Insulin sensitivity is independent of lipid binding protein trafficking at the plasma membrane in human skeletal muscle: Effect of a 3-day, high-fat diet

    Jordy, A. B., Serup, A. K., Karstoft, K., Pilegaard, Henriette, Kiens, Bente & Jeppesen, J. F., 2014, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 307, 9, p. R1136-R1145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Control of gene expression and mitochondrial biogenesis in the muscular adaption to endurance exercise

    Joseph, A. M., Pilegaard, Henriette, Leick, L. & Hood, D. A., 2006, In: Essays in Biochemistry. 42, p. 13-29

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Interstitial K+ in human skeletal muscle during and after dynamic graded exercise determined by microdialysis

    Juel, C., Pilegaard, Henriette, Nielsen, Jens Jung & Bangsbo, Jens, 2000, In: Am. J. Physiol. Regulatory Integrative Comp. Physiol.. 278, p. R400-R406

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Lactate exchange and pH regulation in skeletal muscle

    Juel, C. & Pilegaard, Henriette, 1998, Biochemistry of Exercise. Human Kinetics, p. 185-200

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  78. Published

    Muscle lactate transport studied in sarcolemmal giant vesicles: dependence on fibertype and age

    Juel, C., Honig, A. & Pilegaard, Henriette, 1991, In: Acta Physiologica (Print Edition). 143, 4, p. 361-365

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Interstitial K+ in human skeletal muscle during and after dynamic graded exercise determined by microdialysis

    Juel, C., Pilegaard, Henriette, Nielsen, Jens Jung & Bangsbo, Jens, 2000, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 278, 2, p. R400-R406 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Kinetics of lactate transport in sarcolemmal giant vesicles obtained from human skeletal muscle

    Juel, C., Kristiansen, S., Pilegaard, Henriette, Wojtaszewski, Jørgen F P & Richter, Erik A., 1994, In: Journal of Applied Physiology. 76, 3, p. 1031-1036 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Lactate/H+ transport kinetics in rat skeletal muscle related to fibre type and changes in transport capacity

    Juel & Pilegaard, Henriette, 1998, In: Pflügers Archiv: European Journal of Physiology. 436, 4, p. 560-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle

    Jørgensen, S. B., Wojtaszewski, Jørgen F P, Viollet, B., Andreelli, F., Birk, Jesper Bratz, Hellsten, Ylva, Schjerling, Peter, Vaulont, S., Neufer, P. D., Richter, Erik A. & Pilegaard, Henriette, 2005, In: The FASEB Journal. 19, 9, p. 1146-1148 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue.

    Jørgensen, Stine Ringholm, Knudsen, Jakob Grunnet, Leick, L., Lundgaard, A., Munk Nielsen, M. & Pilegaard, Henriette, 2013, In: PloS one. 8, 5, p. 1-6 6 p., e64123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle

    Jørgensen, Stine Ringholm, Biensø, R. S., Kiilerich, K., Guadalupe-Grau, A., Aachmann-Andersen, N. J., Saltin, B., Plomgaard, Peter Stendahl, Lundby, C., Wojtaszewski, Jørgen F P, Calbet, J. A. & Pilegaard, Henriette, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 301, 4, p. E649-E658 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    PGC-1{alpha} increases PDH content but does not change acute PDH regulation in mouse skeletal muscle

    Kiilerich, K., Adser, H., Jakobsen, A. H., Pedersen, Per Amstrup, Hardie, D. G., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 299, 5, p. R1350-R1359 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest

    Kiilerich, K., Jørgensen, Stine Ringholm, Biensø, R. S., Fisher, J. P., Iversen, N., van Hall, Gerrit, Wojtaszewski, Jørgen F P, Saltin, B., Lundby, C., Calbet, J. A. L. & Pilegaard, Henriette, 2011, In: Journal of Applied Physiology. 111, 3, p. 751-757 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Regulation of PDH in human arm and leg muscles at rest and during intense exercise

    Kiilerich, K., Birk, Jesper Bratz, Damsgaard, R., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 294, 1, p. E36-E42 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Low muscle glycogen and elevated plasma free fatty acid modify but do not prevent exercise-induced PDH activation in human skeletal muscle

    Kiilerich, K., Gudmundsson, M., Birk, Jesper Bratz, Lundby, C., Taudorf, S., Plomgaard, Peter Stendahl, Saltin, B., Pedersen, Per Amstrup, Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2010, In: Diabetes. 59, 1, p. 26-32 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Lack of AMPKalpha2 enhances pyruvate dehydrogenase activity during exercise

    Klein, D. K., Pilegaard, Henriette, Treebak, Jonas Thue, Jensen, Thomas Elbenhardt, Viollet, B., Schjerling, Peter & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 5, p. E1242-E1249 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Exercise-induced regulation of key factors in substrate choice and gluconeogenesis in mouse liver

    Knudsen, Jakob Grunnet, Biensø, R. S., Hassing, H. A., Jakobsen, A. H. & Pilegaard, Henriette, 2015, In: Molecular and Cellular Biochemistry. 403, 1-2, p. 209-217 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Skeletal muscle IL-6 regulates muscle substrate utilization and adipose tissue metabolism during recovery from an acute bout of exercise

    Knudsen, Jakob Grunnet, Gudiksen, Anders, Bertholdt, L., Overby, P., Villesen, I., Schwartz, C. L. & Pilegaard, Henriette, 18 Dec 2017, In: PLoS ONE. 12, 12, 19 p., e0189301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue

    Knudsen, Jakob Grunnet, Murholm, M., Carey, A. L., Biensø, R. S., Basse, A. L., Allen, T. L., Hidalgo, J., Kingwell, B. A., Febbraio, M. A., Hansen, Jacob B. & Pilegaard, Henriette, 2014, In: P L o S One. 9, 1, 8 p., e84910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training

    Knudsen, Jakob Grunnet, Joensen, E., Bertholdt, L., Jessen, H., van Hauen, L., Hidalgo, J. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 9, 9 p., e12788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

    Knudsen, Jakob Grunnet, Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, Henriette, 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Brain-derived neurotrophic factor (BDNF) and type 2 diabetes.

    Krabbe, K. S., Nielsen, A. R., Krogh-Madsen, R., Plomgaard, P., Rasmussen, P., Erikstrup, C., Fischer, C. P., Fischer, C. P., Lindegaard, B., Petersen, A. M., Taudorf, S., Secher, N. H., Pilegaard, Henriette, Bruunsgaard, H. & Pedersen, B. K., 2006, In: Diabetologia. 50 (2), p. 431-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Genetic priming of a proinflammatory profile predicts low IQ in octogenarians

    Krabbe, K. S., Mortensen, Erik Lykke, Avlund, K., Pilegaard, Henriette, Christiansen, L., Pedersen, A. N., Schroll, M., Jørgensen, T., Pedersen, Bente Klarlund & Kemp, H. B., 2007, In: Neurobiology of Aging. 30, p. 769-781

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Calcium signalling in the regulation of PGC-1alpha, PDK4 and HKII mRNA expression

    Kusuhara, K., Madsen, K., Jensen, L., Hellsten, Ylva & Pilegaard, Henriette, 2007, In: Biological Chemistry. 388, 5, p. 481-488 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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