Henriette Pilegaard

Henriette Pilegaard

Professor

ORCID: 0000-0002-1071-0327

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  1. Published

    Menopause is associated with decreased whole body fat oxidation during exercise

    Abildgaard, J., Pedersen, Anette Tønnes, Green, C. J., Majlund Harder-Lauridsen, N., Solomon, T. P., Thomsen, C., Juul, A., Pedersen, M., Pedersen, J. T., Mortensen, Ole Hartvig, Pilegaard, Henriette, Pedersen, Bente Klarlund & Lindegaard, B., 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 11, p. E1227-E1236 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle

    Adhihetty, P. J., Uguccioni, G., Leick, L., Hidalgo, J., Pilegaard, Henriette & Hood, D. A., 2009, In: American Journal of Physiology: Cell Physiology. 297, 1, p. C217-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown and increased IL-6 release

    Bach, E., Nielsen, R. R., Vendelbo, M., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, Henriette, Biensøe, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Diabetes. 62, 12, p. 4023-4029

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Impact of skeletal muscle IL-6 on subcutaneous and visceral adipose tissue metabolism immediately after high- and moderate-intensity exercises

    Bertholdt, L., Gudiksen, Anders, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 217-233 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lack of skeletal muscle IL-6 influences hepatic glucose metabolism in mice during prolonged exercise

    Bertholdt, L., Gudiksen, Anders, Schwartz, C. L., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 7 Apr 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 4, p. R626-R636 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Bed Rest-Induced Changes in TBC1D4 Phosphorylation and Glycogen Synthase Activity. Effects of Acute Exercise

    Bienso, R. S., Ringholm, S., Lundby, C., Achman-Andersen, N. J., Plomgaard, Peter Stendahl, Krogh-Madsen, Rikke, Kiilerich, K., Guerra, B., Treebak, Jonas Thue, Calbet, J. A., Pilegaard, Henriette & Wojtaszewski, J. J. F., 2010, In: Diabetes.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Exercise-induced AMPK and pyruvate dehydrogenase regulation is maintained during short-term low-grade inflammation

    Biensø, R. S., Olesen, J., van Hauen, L., Meinertz, S., Halling, J. F., Gliemann, Lasse, Plomgaard, P. & Pilegaard, Henriette, 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 2, p. 341-350 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes 2012;61:1090-1099

    Biensø, R. S., Ringholm, S., Kiilerich, K., Aachmann-Andersen, N., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2014, In: Diabetes. 63, 9, 1 p., 3159.

    Research output: Contribution to journal › Comment/debate › Research

  11. Published

    Effects of IL-6 on pyruvate dehydrogenase regulation in mouse skeletal muscle

    Biensø, R. S., Knudsen, Jakob Grunnet, Brandt, N., Pedersen, Per Amstrup & Pilegaard, Henriette, 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 8, p. 1647-1657 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance

    Biensø, R. S., Jørgensen, Stine Ringholm, Kiilerich, K., Aachmann-Andersen, N. J., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2012, In: Diabetes. 61, 5, p. 1090-1099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effects of exercise training on regulation of skeletal muscle glucose metabolism in elderly men

    Biensø, R. S., Olesen, J., Gliemann, Lasse, Schmidt, J. F., Matzen, M. S., Wojtaszewski, Jørgen F P, Hellsten, Ylva & Pilegaard, Henriette, 2015, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 70, 7, p. 866-872 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle

    Brandauer, J., Vienberg, S. G., Andersen, M. A., Jørgensen, Stine Ringholm, Risis, S., Larsen, P., Kristensen, Jonas Møller, Frøsig, C., Leick, L., Fentz, J., Jørgensen, S. B., Kiens, Bente, Wojtaszewski, Jørgen F P, Richter, Erik A., Zierath, Juleen R, Goodyear, L. J., Pilegaard, Henriette & Treebak, Jonas Thue, 2013, In: Journal of Physiology. 591, p. 5207-5220 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    IL-6 regulates exercise and training-induced adaptations in subcutaneous adipose tissue in mice

    Brandt, C., Jakobsen, A. H., Hassing, H. A., Olesen, Jes, Iversen, N., Kristensen, Jonas Møller, Hojman, P., Wojtaszewski, Jørgen F P, Hidalgo, J. & Pilegaard, Henriette, 2012, In: Acta Physiologica (Print). 205, 2, p. 224-235 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Impact of adrenaline and metabolic stress on exercise-induced intracellular signaling and PGC-1α mRNA response in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Hostrup, Morten, Tybirk, J., Nybo, Lars, Pilegaard, Henriette & Bangsbo, Jens, 2016, In: Physiological Reports. 4, 14, 13 p., e12844.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle

    Brandt, N., Dethlefsen, M. M., Bangsbo, Jens & Pilegaard, Henriette, 2017, In: P L o S One. 12, 10, 21 p., e0185993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    LIF is a contraction-induced myokine stimulating human myocyte proliferation

    Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, Henriette, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2011, In: Journal of Applied Physiology. 111, 1, p. 251-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner

    Buch, B. T., Halling, Jens Frey, Jørgensen, Stine Ringholm, Gudiksen, Anders, Kjøbsted, Rasmus, Olsen, M. A., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2020, In: F A S E B Journal. 34, 6, p. 8653-8670

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg

    Buhl, M., Bosnjak, E., Vendelbo, M. H., Gjedsted, J., Nielsen, R. R., Hafstrøm, T. K., Vestergaard, E. T., Jessen, N., Tønnesen, E., Møller, A. B., Pedersen, S. B., Pilegaard, Henriette, Biensø, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 5, p. 2090-2099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion

    Carey, A., Wolsk, E., Bruce, C., Southgate, R., Pilegaard, Henriette, Hawley, J. A., Pedersen, B. K. & Febrario, M., 2006, In: Diabetologia. 49, 5, p. 1000-1007

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects

    Christensen, B., Lundby, C., Jessen, N., Nielsen, Thomas Svava, Vestergaard, P. F., Møller, N., Pilegaard, Henriette, Pedersen, S. B., Kopchick, J. J. & Jørgensen, J. O. L., 2012, In: P L o S One. 7, 2, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Muscle PGC-1α modulates hepatic mitophagy regulation during aging

    Christensen, N. M., Jørgensen, Stine Ringholm, Buch, B. T., Gudiksen, Anders, Halling, Jens Frey & Pilegaard, Henriette, 2023, In: Experimental Gerontology. 172, 9 p., 112046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle

    Coffey, V. G., Pilegaard, Henriette, Garnham, A. P., O'Brien, B. J. & Hawley, J. A., 2009, In: Journal of Applied Physiology. 106, 4, p. 1187-97 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock

    Dyar, K. A., Ciciliot, S., Wright, L. E., Biensø, R. S., Tagliazucchi, G. M., Patel, V. R., Forcato, M., Paz, M. I. P., Gudiksen, Anders, Solagna, F., Albiero, M., Moretti, I., Eckel-Mahan, K. L., Baldi, P., Sassone-Corsi, P., Rizzuto, R., Bicciato, S., Pilegaard, Henriette, Blaauw, B. & Schiaffino, S., 2014, In: Molecular Metabolism. 3, 1, p. 29-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle

    Edge, J., Muendel, T., Pilegaard, Henriette, Hawke, E., Leikis, M., Lopez-Villalobos, N., Oliveira, R. S. F. & Bishop, D. J., 2015, In: P L o S One. 10, 12, 14 p., e0141317.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9

    Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle

    Fentz, J., Kjøbsted, Rasmus, Maag Kristensen, C., Hingst, J. R., Birk, Jesper Bratz, Gudiksen, Anders, Foretz, M., Schjerling, Peter, Viollet, B., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 309, 11, p. E900-E914 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle

    Fischer, C. P., Plomgaard, P., Hansen, A. K., Pilegaard, Henriette, Saltin, B. & Pedersen, B. K., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, p. E-1189-E1194

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    5´AMP activated protein kinase α2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jeppesen, J., Christiansen, M. L. B., Biensø, R. S., Dyck, J. R. B., Pilegaard, Henriette & Kiens, Bente, 2015, In: Journal of Physiology. 593, 21, p. 4765-4780 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    New Nordic Diet induced weight loss is accompanied by changes in metabolism and AMPK signalling in adipose tissue

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jordy, A. B., Poulsen, S. K., Stender, Steen, Pilegaard, Henriette, Astrup, A., Larsen, T. M., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 9, p. 3509-3519 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Reply from Lasse Gliemann, Jesper Olesen, Rasmus Sjørup Biensø, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Olesen, J., Biensø, R. S., Mortensen, S. P., Nyberg, M. P., Schmidt, J. F., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 3, p. 553 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  40. Published

    Reply from Lasse Gliemann, Jakob Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Schmidt, J., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5253 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  41. Published

    Effects of training status on PDH regulation in human skeletal muscle during exercise

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Tybirk, J., Plomgaard, Peter Stendahl, Bangsbo, Jens & Pilegaard, Henriette, 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 12, p. 1615-1630 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue

    Gudiksen, Anders, Qoqaj, A., Jørgensen, Stine Ringholm, Wojtaszewski, Jørgen F P, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2022, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 77, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Lack of skeletal muscle IL-6 affects pyruvate dehydrogenase activity at rest and during prolonged exercise

    Gudiksen, Anders, Schwartz, C. L., Bertholdt, L., Joensen, E., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 2016, In: P L o S One. 11, 6, 17 p., e0156460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders & Pilegaard, Henriette, 10 Apr 2017, In: Physiological Reports. 5, 7, 15 p., e13222.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Vingborg, M. B., Hansen, H. W., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E204-E214 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Leptin signaling in skeletal muscle after bed rest in healthy humans

    Guerra, B., Ponce-Gonzalez, J. G., Morales-Alamo, D., Guadalupe-Grau, A., Kiilerich, K., Fuentes, T., Jørgensen, Stine Ringholm, Biensø, R. S., Santana, A., Lundby, C., Pilegaard, Henriette & Calbet, J. A. L., 2014, In: European Journal of Applied Physiology. 114, 2, p. 345-357 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Inclusion of sprints in moderate intensity continuous training leads to muscle oxidative adaptations in trained individuals

    Gunnarsson, T. G. P., Brandt, N., Fiorenza, Matteo, Hostrup, Morten, Pilegaard, Henriette & Bangsbo, Jens, 2019, In: Physiological Reports. 7, 4, 15 p., e13976.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Role of PGC-1{alpha} in exercise and fasting induced adaptations in mouse liver

    Haase, T. N., Jørgensen, S. R., Leick, L., Biensø, R. S., Kiilerich, K., Johansen, S., Nielsen, M. M., Wojtaszewski, Jørgen F P, Hidalgo, J., Pedersen, Per Amstrup & Pilegaard, Henriette, 2011, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 301, 5, p. R1501-R1509 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Nielsen, M. M., Overby, P. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 3, 11 p., e12698.

    Research output: Contribution to journal › Journal article › Research › peer-review

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