Ian Henry Lambert

Ian Henry Lambert

Associate Professor emeritus


  1. 2022
  2. Published

    In Vitro Characterization of a Threonine-Ligated Molybdenyl-Sulfide Cluster as a Putative Cyanide Poisoning Antidote: Intracellular Distribution, Effects on Organic Osmolyte Homeostasis, and Induction of Cell Death

    Gretarsdottir, J. M., Lambert, Ian Henry, Stürup, Stefan & Suman, S. G., 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 907–918

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2020
  4. Published

    Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells

    Lambert, Ian Henry, Nielsen, D. & Stürup, Stefan, 2020, In: American journal of physiology. Cell physiology. 318, 3, p. C581-C597

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2019
  6. Published

    Distribution of platinum between nuclear and cytosolic fractions: can subcellular fractionation be performed quantitatively?

    Dam, C. S., Lambert, Ian Henry, Gammelgaard, Bente & Stürup, Stefan, 2019, In: Journal of Pharmaceutical and Biomedical Analysis. 165, p. 82-89 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2018
  8. Published

    Facilitating the Cellular Accumulation of Pt-Based Chemotherapeutic Drugs

    Lambert, Ian Henry & Sørensen, B. H., 1 Aug 2018, In: International Journal of Molecular Sciences . 19, 8, p. 1-19 2249.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(II) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

    Sørensen, B. H., Werth, P., Lambert, Ian Henry & Bednarski, P. J., 2018, In: Metallomics. 10, 2, p. 323-336 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods

    Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine

    Rubino, S., Bach, M. D., Schober, A. L., Lambert, Ian Henry & Mongin, A. A., 2018, In: Frontiers in Oncology. 8, 12 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Stress-induced modulation of volume-regulated anions channels in human alveolar carcinoma cells

    Bach, M. D., Sørensen, B. H. & Lambert, Ian Henry, 2018, In: Physiological Reports. 6, 19, p. 1-22 e13869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2017
  14. Published

    Sliding doors: heteromeric, volume-sensitive osmolyte channels

    Lambert, Ian Henry, 15 Nov 2017, In: The Journal of Physiology. 595, 22, p. 6807-6807 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  15. Published

    MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism

    Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, Marie Sophie, Markussen, L. K., Viuff, B. M., Lambert, Ian Henry, Hansen, Jacob B. & Pedersen, Stine Helene Falsig, 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mitigating Cyanide Poisoning

    Suman, S. G., Gretarsdottir, J. M., Lambert, Ian Henry & Stürup, Stefan, Jul 2017, p. S261-S261.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  17. 2016
  18. Published

    Cellular uptake of metallated cobalamins

    Tran, M. T. Q., Stürup, Stefan, Lambert, Ian Henry, Gammelgaard, Bente, Furger, E. & Alberto, R., 2016, In: Metallomics. 8, 3, p. 298-304 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1 and Caspase-9/-3 activation

    Sørensen, B. H., Nielsen, D., Thorsteinsdottir, U. A., Hoffmann, E. K. & Lambert, Ian Henry, 2016, In: American Journal of Physiology: Cell Physiology. 310, 11, p. C857-C873 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells

    Sørensen, B. H., Dam, C. S., Stürup, Stefan & Lambert, Ian Henry, 2016, In: Journal of Inorganic Biochemistry. 160, p. 287-295 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Protolichesterinic acid, isolated from the lichen Cetraria islandica, reduces LRRC8A expression and volume-sensitive release of organic osmolytes in human lung epithelial cancer cells

    Thorsteinsdottir, U. A., Thorsteinsdottir, M. & Lambert, Ian Henry, 2016, In: Phytotherapy Research. 30, 1, p. 97-104 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2015
  23. Published

    In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis

    Dam, C. S., Henarejos, S. A. P., Tsolakou, T., Segato, C. A., Gammelgaard, Bente, Yellol, G. S., Ruiz, J., Lambert, Ian Henry & Stürup, Stefan, 2015, In: Metallomics. 5, p. 885-895 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Integrin β1, osmosensing, and chemoresistance in mouse ehrlich carcinoma cells

    Sørensen, B. H., Rasmussen, L. J. H., Broberg, B. S., Klausen, T. K., Sauter, D. R. P., Lambert, Ian Henry, Aspberg, A. & Hoffmann, E. K., 2015, In: Cellular Physiology and Biochemistry. 36, 1, p. 111-132 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Physiological role of taurine - from organism to organelle

    Lambert, Ian Henry, Kristensen, D. M. B., Holm, J. B. & Mortensen, Ole Hartvig, 2015, In: Acta Physiologica (Print). 213, 1, p. 191-212 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Regulation of p53 in NIH3T3 mouse fibroblasts following hyperosmotic stress

    Lambert, Ian Henry, Enghoff, M. S., Brandi, M. & Hoffmann, E. K., 2015, In: Physiological Reports. 3, 6, 9 p., e12412.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance

    Hoffmann, E. K., Sørensen, B. H., Sauter, D. R. P. & Lambert, Ian Henry, 2015, In: Channels (Austin). 9, 6, p. 380-396 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2014
  29. Published

    Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate

    Sørensen, B. H., Thorsteinsdottir, U. A. & Lambert, Ian Henry, 2014, In: American Journal of Physiology: Cell Physiology. 307, 12, p. C1071-C1080 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca2+

    Juul, C. A., Grubb, S., Poulsen, K. A., Kyed, T., Hashem, N., Lambert, Ian Henry, Larsen, Erik Hviid & Hoffmann, E. K., 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 10, p. 1899-1910 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Functions of volume-sensitive and calcium-activated chloride channels

    Hoffmann, E. K., Holm, N. B. & Lambert, Ian Henry, 2014, In: I U B M B Life. 66, 4, p. 257-267 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Ion channels and transporters in the development of drug resistance in cancer cells

    Hoffmann, E. K. & Lambert, Ian Henry, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    mTOR ensures increased release and reduced uptake of the organic osmolyte taurine under hypoosmotic conditions in mouse fibroblasts

    Lambert, Ian Henry, Jensen, J. V. & Pedersen, Per Amstrup, 2014, In: American Journal of Physiology: Cell Physiology. 306, 11, p. C1028-C1040 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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