Ian Henry Lambert
Associate Professor emeritus
Cell Biology and Physiology
Universitetsparken 13
2100 København Ø
- Published
12th Acta Physiologica International Symposium "cell volume control in health and disease.".
Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 1-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Characterization of a Threonine-Ligated Molybdenyl-Sulfide Cluster as a Putative Cyanide Poisoning Antidote: Intracellular Distribution, Effects on Organic Osmolyte Homeostasis, and Induction of Cell Death
Gretarsdottir, J. M., Lambert, Ian Henry, Stürup, Stefan & Suman, S. G., 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 907–918Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis
Dam, C. S., Henarejos, S. A. P., Tsolakou, T., Segato, C. A., Gammelgaard, Bente, Yellol, G. S., Ruiz, J., Lambert, Ian Henry & Stürup, Stefan, 2015, In: Metallomics. 5, p. 885-895 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(II) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis
Sørensen, B. H., Werth, P., Lambert, Ian Henry & Bednarski, P. J., 2018, In: Metallomics. 10, 2, p. 323-336 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate
Sørensen, B. H., Thorsteinsdottir, U. A. & Lambert, Ian Henry, 2014, In: American Journal of Physiology: Cell Physiology. 307, 12, p. C1071-C1080 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation and inactivation of the volume-sensitive taurine leak pathway in NIH3T3 fibroblasts and Ehrlich Lettre ascites cells.
Lambert, Ian Henry, 2007, In: American Journal of Physiology: Cell Physiology. 293, 1, p. C390-400Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia
Lambert, Ian Henry, Pedersen, Stine Helene Falsig & Poulsen, K. A., 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 75-85Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of the TASK-2 channel after cell swelling is dependent on tyrosine phosphorylation
Kirkegaard, S. S., Lambert, Ian Henry, Gammeltoft, S. & Hoffmann, E. K., 1 Oct 2010, In: American Journal of Physiology (Consolidated). 299, 4, p. C844-53Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute cholesterol depletion leads to net loss of the organic osmolyte taurine in Ehrlich Lettré tumor cells
Villumsen, Kasper Rømer, Duelund, L. & Lambert, Ian Henry, 1 Nov 2010, In: Amino Acids. 39, 5, p. 1521-36 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca2+
Juul, C. A., Grubb, S., Poulsen, K. A., Kyed, T., Hashem, N., Lambert, Ian Henry, Larsen, Erik Hviid & Hoffmann, E. K., 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 10, p. 1899-1910 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ca2+-mediated potentiation of the swelling-induced taurine efflux from HeLa cells: On the role of calmodulin and novel protein kinase C isoforms
Falktoft, B. & Lambert, Ian Henry, 2004, In: Journal of Membrane Biology. 201, 2, p. 59-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calyculin A modulates the kinetic constants for the Na+-coupled taurine transport in Ehrlich ascites tumour cells
Mollerup, J. & Lambert, Ian Henry, 1998, In: BBA General Subjects. 1371, p. 335-344Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Casein kinase 2 regulates the active uptake of the organic osmolyte taurine in NIH3T3 mouse fibroblasts
Jacobsen, J. H., Clement, C. A., Friis, M. B. & Lambert, Ian Henry, 1 Nov 2008, In: Pflügers Archiv - European Journal of Physiology. 457, 2, p. 327-37 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell Shrinkage is Essential in Lysophosphatidic Acid Signaling in Ehrlich Ascites
Pedersen, S., Hoffmann, E. K., Hougaard, C. & Lambert, Ian Henry, 2000, In: Journal of Membrane Biology. 173, 1, p. 19-29Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell Swelling Activates Phospholipase A2 in Ehrlich Ascites Tumor Cells
Thoroed, S. M., Lauritzen, Lotte, Lambert, Ian Henry, Hansen, Harald S. & Hoffmann, E. K., 1 Jan 1997, In: Journal of Membrane Biology. 160, 1, p. 47-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell Volume Regulation and Signaling in 3T3-L1 Pre-adipocytes and Adipocytes: on the Possible Roles of Caveolae, Insulin Receptors, FAK and ERK1/2
Eduardsen, K., Larsen, S., Novak, Ivana, Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1231-46 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts.
Friis, M. B., Friborg, C. R., Schneider, L., Nielsen, M., Lambert, Ian Henry, Christensen, Søren Tvorup & Hoffmann, E. K., 2005, In: Journal of Physiology. 567, 2, p. 427-43 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell swelling activates separate taurine and chloride channels in Ehrlich mouse ascites tumor cells.
Lambert, Ian Henry & Hoffmann, E. K., 1994, In: Journal of Membrane Biology. 142, 3, p. 289-298Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell swelling stimulates the Ca2+-sensitive cytosolic phospholipase A2 in Ehrlich ascites tumour cells.
Thoroed, S. M., Lambert, Ian Henry, Hansen, H. S. & Hoffmann, E. K., 1994, In: Acta Physiologica Scandinavica. Supplementum. 4, p. 25AResearch output: Contribution to journal › Conference article › Research › peer-review
- Published
Cell volume regulation: Intracellular transmission.
Hoffmann, E. K., Simonsen, L. O. & Lambert, Ian Henry, 1993, In: Advances in Comparative and Environmental Physiology. Vol. 14, p. 187-248Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell volume regulation: physiology and pathophysiology
Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2008, In: Acta Physiologica (Print Edition). 194, 4, p. 255-82 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular Model for Induction of Drip Loss in Meat
Lambert, Ian Henry, Nielsen, J. H., Andersen, H. J. & Ørtenblad, N., 2001, In: Journal of Agricultural and Food Chemistry. Vol. 49, No. 10, p. 4876-4883Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular uptake of metallated cobalamins
Tran, M. T. Q., Stürup, Stefan, Lambert, Ian Henry, Gammelgaard, Bente, Furger, E. & Alberto, R., 2016, In: Metallomics. 8, 3, p. 298-304 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deregulation of apoptotic volume decrease and ionic movements in multidrug-resistant tumor cells: role of chloride channels
Poulsen, K. A., Andersen, E. C., Hansen, C. F., Klausen, T. K., Hougaard, C., Lambert, Ian Henry & Hoffmann, E. K., 2010, In: American Journal of Physiology: Cell Physiology. 298, 1, p. C14-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods
Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential regulation of iPLA2beta splice variants by in vitro ischemia in C2C12 myotubes
Poulsen, K. A., Kolko, M. & Lambert, Ian Henry, 2006, In: The FASEB Journal. 20, 5, p. A1431-A1432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of platinum between nuclear and cytosolic fractions: can subcellular fractionation be performed quantitatively?
Dam, C. S., Lambert, Ian Henry, Gammelgaard, Bente & Stürup, Stefan, 2019, In: Journal of Pharmaceutical and Biomedical Analysis. 165, p. 82-89 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization
Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1 and Caspase-9/-3 activation
Sørensen, B. H., Nielsen, D., Thorsteinsdottir, U. A., Hoffmann, E. K. & Lambert, Ian Henry, 2016, In: American Journal of Physiology: Cell Physiology. 310, 11, p. C857-C873 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine
Rubino, S., Bach, M. D., Schober, A. L., Lambert, Ian Henry & Mongin, A. A., 2018, In: Frontiers in Oncology. 8, 12 p., 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells
Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, Jun 2002, In: Amino Acids. 22, 4, p. 333-50 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells
Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, 2002, In: Amino Acids. 22, p. 333-350Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of the taurine transporter TauT during hypo-osmotic stress in NIH3T3 mouse fibroblasts
Hansen, D. B., Friis, M. B., Hoffmann, E. K. & Lambert, Ian Henry, 2012, In: Journal of Membrane Biology. 245, 2, p. 77-87 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells
Sørensen, B. H., Dam, C. S., Stürup, Stefan & Lambert, Ian Henry, 2016, In: Journal of Inorganic Biochemistry. 160, p. 287-295 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Urea and Osmotic Cell Shrinkage on Ca2+ Entry and Contraction of Cascular Smooth Muscle Cells
Wagner, C. A., Huber, S. M., Warntges, S., Zempel, G., Kaba, N. K., Fux, R. R., Orth, N., Busch, G. L., Waldegger, S., Lambert, Ian Henry, Nilius, B. H. & Lang, F., 2000, In: Pflugers Arch.. 440, p. 295-301Research output: Contribution to journal › Journal article › Research
- Published
Effects of polyunsaturated fatty acids on ion transport properties of frog skin epithelium.
Unmack, M. A., Lambert, Ian Henry & Willumsen, N. J., 1994, In: Acta Physiologica (Print Edition). 151, p. 17AResearch output: Contribution to journal › Journal article › Research
- Published
Eicosanoids and cell volume regulation
Lambert, Ian Henry, 1994, Cellular and Molecular Physiology of Cell Volume Regulation. Boca Raton, FL: CRC Press, p. 279-298Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Facilitating the Cellular Accumulation of Pt-Based Chemotherapeutic Drugs
Lambert, Ian Henry & Sørensen, B. H., 1 Aug 2018, In: International Journal of Molecular Sciences . 19, 8, p. 1-19 2249.Research output: Contribution to journal › Review › Research › peer-review
- Published
Functional expression of a murine leukotriene B4 receptor in Xenopus laevis oocytes.
Mollerup, J., Lambert, Ian Henry, Hoffmann, E. K. & Jensen, B. S., 1999, In: Acta Physiologica (Print Edition). 165, p. CP22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functions of volume-sensitive and calcium-activated chloride channels
Hoffmann, E. K., Holm, N. B. & Lambert, Ian Henry, 2014, In: I U B M B Life. 66, 4, p. 257-267 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange
Andersen, A., Poulsen, K. A., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: American Journal of Physiology: Cell Physiology. 296, 5, p. C1227-42Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High expression of the taurine transporter TauT in primary cilia of NIH3T3 fibroblasts
Christensen, Søren Tvorup, Voss, J. W., Teilmann, S. C. & Lambert, Ian Henry, 2005, In: Cell Biology International. 29, 5, p. 347-351Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High expression of the taurine transporter TauT in the primary cilium of NIH3T3 fibroblasts
Voss, J. W., Christensen, Søren Tvorup, Lambert, Ian Henry & Teilmann, S. C., 2004, In: Molecular Biology of the Cell. vol. 15, p. 281aResearch output: Contribution to journal › Journal article › Research › peer-review
- Published
Homologous desensitisation of the mouse leukotriene B4 receptor involves protein kinase C-mediated phosphorylation of serine 127.
Mollerup, J., Eriksen, H. N., Albertsen, J., Wulff, T., Lambert, Ian Henry & Hoffmann, E. K., 2007, In: Cellular Physiology and Biochemistry. 20, 1-4, p. 143-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypotonic cell swelling induces translocation of the a isoform of cytosolic phospholipase A2 but not the ¿ isoform in Ehrlich ascites tumor cells
Pedersen, S., Lambert, Ian Henry, Thoroed, S. M. & Hoffmann, E. K., 2000, In: European Journal of Biochemistry. 267, p. 5531-5539Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells
Lambert, Ian Henry, Nielsen, D. & Stürup, Stefan, 2020, In: American journal of physiology. Cell physiology. 318, 3, p. C581-C597Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of group VIA phospholipase A2 activity during in vitro ischemia in C2C12 myotubes is associated with changes in the level of its splice variants.
Poulsen, K. A., Pedersen, Stine Helene Falsig, Kolko, M. & Lambert, Ian Henry, 2007, In: American Journal of Physiology: Cell Physiology. 293, 5, p. C1605-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrin β1, osmosensing, and chemoresistance in mouse ehrlich carcinoma cells
Sørensen, B. H., Rasmussen, L. J. H., Broberg, B. S., Klausen, T. K., Sauter, D. R. P., Lambert, Ian Henry, Aspberg, A. & Hoffmann, E. K., 2015, In: Cellular Physiology and Biochemistry. 36, 1, p. 111-132 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracellular signalling by lipid second messengers in Ehrlich ascites tumor cells.
Pedersen, S., Hoffmann, E. K. & Lambert, Ian Henry, 1999, In: Acta Physiologica (Print Edition). 165, p. CP21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ion channels and transporters in the development of drug resistance in cancer cells
Hoffmann, E. K. & Lambert, Ian Henry, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5814
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Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca2+
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
273
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Integrin β1, osmosensing, and chemoresistance in mouse ehrlich carcinoma cells
Research output: Contribution to journal › Journal article › Research › peer-review
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217
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Cellular uptake of metallated cobalamins
Research output: Contribution to journal › Journal article › Research › peer-review
Published