Søren Tvorup Christensen

Søren Tvorup Christensen

Professor

ORCID: 0000-0001-5004-304X

Publication year:
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1 - 50 out of 122Page size: 50
  1. 2023
  2. Published

    Cilia and flagella

    Pedersen, Lotte Bang, Jurisch-Yaksi, N., Schmid, F. M. & Christensen, Søren Tvorup, 2023, Encyclopedia of Cell Biology, Second Edition. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Oxford: Elsevier, Vol. 3. p. 164-188 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  3. Published

    Editorial: Signaling by primary cilia in development and disease

    Kim, S. E., Nechipurenko, I. & Christensen, Søren Tvorup, 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1186367.

    Research output: Contribution to journal › Editorial › Research › peer-review

  4. Published

    Expression of genes and enzymes involved in ovarian steroidogenesis in relation to human follicular development

    Zheng, M., tcg964, tcg964, Rasmussen, F. R., Cadenas, J., Christensen, Søren Tvorup & Mamsen, L. S., 2023, In: Frontiers in Endocrinology. 14, 17 p., 1268248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Primary cilia as dynamic and diverse signalling hubs in development and disease

    Mill, P., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2023, In: Nature Reviews. Genetics. 24, 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

    Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling

    Morthorst, Stine Kjær, Nielsen, C., Farinelli, P., Anvarian, Zeinab, Rasmussen, C. B. R., Serra-Marques, A., Grigoriev, I., Altelaar, M., Fürstenberg, N., Ludwig, A., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2022, In: Journal of Cell Science. 135, 12, 10 p., jcs259471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Peter Satir (1936-2022), cell biology pioneer and mentor

    Sale, W. S. & Christensen, Søren Tvorup, 2022, In: Journal of Cell Science. 135, 23

    Research output: Contribution to journal › Comment/debate › Research

  10. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2021
  12. Published

    ALMS1 Regulates TGF-β Signaling and Morphology of Primary Cilia

    Álvarez-Satta, M., Lago-Docampo, M., Bea-Mascato, B., Solarat, C., Castro-Sánchez, S., Christensen, Søren Tvorup & Valverde, D., 2021, In: Frontiers in Cell and Developmental Biology. 9, 8 p., 623829.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

    Gonçalves, A. B., Hasselbalch, S. K., Joensen, B. B., Patzke, S., Martens, P., Ohlsen, S. K., Quinodoz, M., Nikopoulos, K., Suleiman, R., Jeppesen, M. P. D., Weiss, C., Christensen, Søren Tvorup, Rivolta, C., Andersen, J. S., Farinelli, P. & Pedersen, Lotte Bang, 2021, In: eLife. 10, 34 p., e63731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine

    Christensen, S. L., Rasmussen, R. H., Ernstsen, C., La Cour, S., David, A., Chaker, J., Haanes, K. A., Christensen, Søren Tvorup, Olesen, Jes & Kristensen, D. M., 2021, In: Cephalalgia. 41, 14, p. 1413-1426 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    N-acetylcysteine protects ovarian follicles from ischemia-reperfusion injury in xenotransplanted human ovarian tissue

    Olesen, H. Ø., Pors, S. E., Jensen, L. B., Grønning, A. P., Lemser, C. E., Heimbürger, M. T. H. N., Mamsen, L. S., Getreu, N., Christensen, Søren Tvorup, tcg964, tcg964 & Kristensen, S. G., 2021, In: Human Reproduction. 36, 2, p. 429-443 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis

    Stevens, E. M., Vladar, E. K., Alanin, M. C., Christensen, Søren Tvorup, von Buchwald, Christian & Milla, C., Jan 2020, In: American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 120-123 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Analysis of caveolin in primary cilia

    Morthorst, Stine Kjær, Mogensen, J. B., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2020, Caveolae: Methods and Protocols. Blouin, C. M. (ed.). Humana Press, p. 27-41 (Methods in Molecular Biology, Vol. 2169).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  19. Published

    Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

    Björkman, A., Johansen, S. L., Lin, L., Schertzer, M., Kanellis, D. C., Katsori, A., Christensen, Søren Tvorup, Luo, Y., Andersen, J. S., Elsässer, S. J., Londono-Vallejo, A., Bartek, J. & Schou, K. B., 2020, In: Genes & Development. 34, 15-16, p. 1065-1074 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

    Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2019
  23. Published

    Cellular signalling by primary cilia in development, organ function and disease

    Anvarian, Zeinab, Mykytyn, K., Mukhopadhyay, S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2019, In: Nature Reviews Nephrology. 15, p. 199-219

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

    Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2018
  26. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

    Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

    Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2018, In: F E B S Journal. 285, 24, p. 4535-4564

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms

    Rosengren, T., Larsen, L. J., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Møller, L. B., 2018, In: Cellular and Molecular Life Sciences. 75, 14, p. 2663-2680 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2017
  33. Published

    Hot spots of N2O emission move with the seasonally mobile oxic-anoxic interface in drained organic soils

    Lee, A. J., Winther, M. N., Priemé, Anders, Blunier, Thomas & Christensen, Søren Tvorup, 1 Dec 2017, In: Soil Biology & Biochemistry. 115, p. 178-186 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation

    Vestergaard, M. L., Grubb, Søren, Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, Kirstine, Clausen, C., Christensen, Søren Tvorup, Møllgård, Kjeld & tcg964, tcg964, 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia

    Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.

    Schou, K. B., Mogensen, J. B., Morthorst, Stine Kjær, Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 30 Jan 2017, In: Nature Communications. 8, 15 p., 14177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis

    Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling

    Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2016
  40. Published

    Cilia and flagella

    Schmid, F. M., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2016, Encyclopedia of cell biology. Bradshaw, R. A. & Stahl, P. D. (eds.). 1 ed. Elsevier, Vol. 2. p. 660-676 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research › peer-review

  41. Published

    Endocytic control of cellular signaling at the primary cilium

    Pedersen, Lotte Bang, Mogensen, J. B. & Christensen, Søren Tvorup, 2016, In: Trends in Biochemical Sciences. 41, 9, p. 784-797 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Immunofluorescence Microscopy and mRNA Analysis of Human Embryonic Stem Cells (hESCs) Including Primary Cilia Associated Signaling Pathways

    Vestergaard, M. L., Awan, A., Warzecha, C. B., Christensen, Søren Tvorup & tcg964, tcg964, 2016, Human Embryonic Stem Cell Protocols. Springer Science+Business Media, Vol. 1307. p. 123-140 (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  43. Published

    TGFβ1-induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner

    Labour, M., Riffault, M., Christensen, Søren Tvorup & Hoey, D. A., 2016, In: Scientific Reports. 6, 13 p., 35542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The intraflagellar transport machinery in ciliary signaling

    Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  45. 2015
  46. Published

    Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells

    Nygaard, M. B., Almstrup, Kristian, Lindbæk, L., Christensen, Søren Tvorup & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  48. Published

    Evolutionary implications of localization of the signaling scaffold protein Parafusin to both cilia and the nucleus

    Satir, B. H., Wyroba, E., Liu, L., Lethan, M., Satir, P. & Christensen, Søren Tvorup, 2015, In: Cell Biology International. 39, 2, p. 136-145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia

    Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  50. Published

    Ins and outs of GPCR signaling in primary cilia

    Schou, K. B., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2015, In: E M B O Reports. 16, 9, p. 1099-1113 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Kinesin-3 motor protein KIF13B localizes to centrosomes and primary cilia and regulates ciliary length and signaling

    Schou, K. B., Mogensen, J. B., Aleliunaite, A., Morthorst, Stine Kjær, Veland, I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., O3.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  52. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2014
  54. Published

    Cilia and coordination of signaling networks during heart development

    Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8

    Schou, K. B., Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2014, In: Cilia. 3, 6, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Proteomic analysis of bovine blastocoel fluid and blastocyst cells

    Jensen, P. L., Grøndahl, M. L., Beck, H. C., Petersen, J., Stroebech, L., Christensen, Søren Tvorup & tcg964, tcg964, 2014, In: Systems Biology in Reproductive Medicine. 60, 3, p. 127-135 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2013
  58. Published

    Analysis of primary cilia in directional cell migration in fibroblasts

    Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Proteomic analysis of human blastocoel fluid and blastocyst cells

    Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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