COP9 signalosome: a provider of DNA building blocks

Research output: Contribution to journalJournal articleResearchpeer-review

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COP9 signalosome: a provider of DNA building blocks. / Nielsen, Olaf.

In: Current Biology, Vol. 13, No. 14, 15.07.2003, p. R565-7.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Nielsen, O 2003, 'COP9 signalosome: a provider of DNA building blocks', Current Biology, vol. 13, no. 14, pp. R565-7.

APA

Nielsen, O. (2003). COP9 signalosome: a provider of DNA building blocks. Current Biology, 13(14), R565-7.

Vancouver

Nielsen O. COP9 signalosome: a provider of DNA building blocks. Current Biology. 2003 Jul 15;13(14):R565-7.

Author

Nielsen, Olaf. / COP9 signalosome: a provider of DNA building blocks. In: Current Biology. 2003 ; Vol. 13, No. 14. pp. R565-7.

Bibtex

@article{55fa3f8b95bf4c21813ad84129a2f4b0,
title = "COP9 signalosome: a provider of DNA building blocks",
abstract = "In fission yeast, the COP9 signalosome is required to activate ribonucleotide reductase for DNA synthesis. This is mediated via the ubiquitin ligase Pcu4, activation of which leads to degradation of the scaffold protein Spd1, which anchors the small ribonucleotide reductase subunit in the nucleus away from the large subunit in the cytoplasm.",
keywords = "Cell Cycle, Cullin Proteins, Models, Biological, Multiprotein Complexes, Peptide Hydrolases, Proteins, Ribonucleotide Reductases, Schizosaccharomyces, Ubiquitin-Protein Ligases",
author = "Olaf Nielsen",
year = "2003",
month = jul,
day = "15",
language = "English",
volume = "13",
pages = "R565--7",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "14",

}

RIS

TY - JOUR

T1 - COP9 signalosome: a provider of DNA building blocks

AU - Nielsen, Olaf

PY - 2003/7/15

Y1 - 2003/7/15

N2 - In fission yeast, the COP9 signalosome is required to activate ribonucleotide reductase for DNA synthesis. This is mediated via the ubiquitin ligase Pcu4, activation of which leads to degradation of the scaffold protein Spd1, which anchors the small ribonucleotide reductase subunit in the nucleus away from the large subunit in the cytoplasm.

AB - In fission yeast, the COP9 signalosome is required to activate ribonucleotide reductase for DNA synthesis. This is mediated via the ubiquitin ligase Pcu4, activation of which leads to degradation of the scaffold protein Spd1, which anchors the small ribonucleotide reductase subunit in the nucleus away from the large subunit in the cytoplasm.

KW - Cell Cycle

KW - Cullin Proteins

KW - Models, Biological

KW - Multiprotein Complexes

KW - Peptide Hydrolases

KW - Proteins

KW - Ribonucleotide Reductases

KW - Schizosaccharomyces

KW - Ubiquitin-Protein Ligases

M3 - Journal article

C2 - 12867051

VL - 13

SP - R565-7

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 14

ER -

ID: 33577756