Søren Tvorup Christensen

Søren Tvorup Christensen

Professor


  1. 2008
  2. Published

    Effects of osmotic stress on the activity of MAPKs and PDGFR-beta-mediated signal transduction in NIH-3T3 fibroblasts

    Nielsen, M., Christensen, Søren Tvorup & Hoffmann, E. K., 2008, In: American Journal of Physiology: Cell Physiology. 294, 4, p. C1046-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.

    Schneider, L., Klausen, T. K., Stock, C., Mally, S., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Schwab, A., 2008, In: Pflügers Archiv: European Journal of Physiology. 455, 6, p. 1055-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery.

    Kiprilov, E. N., Awan, A., Desprat, R., Velho, M., Clement, C. A., Byskov, A. G., tcg964, tcg964, Satir, P., Bouhassira, E. E., Christensen, Søren Tvorup & Hirsch, R. E., 2008, In: Journal of Cell Biology. 180, 5, p. 897-904 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Structure and function of mammalian cilia

    Satir, P. & Christensen, Søren Tvorup, 2008, In: Histochemistry and Cell Biology. 129, 6, p. 687-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2009
  7. Published

    Primary cilia and signaling pathways in mammalian development, health and disease

    Veland, I. R., Awan, A., Pedersen, Lotte Bang, Yoder, B. K. & Christensen, Søren Tvorup, 2009, In: NEPHRON PHYSIOLOGY. 111, 3, p. p39-53

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium

    Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

    Clement, C. A., Kristensen, S. G., Møllgård, Kjeld, Pazour, G. J., Yoder, B. K., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, In: Journal of Cell Science. 122, Pt 17, p. 3070-82 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Using Nucleofection of siRNA Constructs for Knockdown of Primary Cilia in P19.CL6 Cancer Stem Cell Differentiation into Cardiomyocytes

    Clement, C. A., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 181-197

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  11. Published

    Using quantitative PCR to Identify Kinesin-3 Genes that are Upregulated During Growth Arrest in Mouse NIH3T3 Cells

    Thorsteinsson, R. I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2009, Primary Cilia. Sloboda, R. D. (ed.). Elsevier, p. 66-86 21 p. (Methods in Cell Biology, Vol. 94).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Published

    Using quantitative PCR to Identify Kinesin-3 Genes that are Upregulated During Growth Arrest in MouseNIH3T3 Cells

    Thorsteinsson, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 66-86

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  13. 2010
  14. Published

    Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts

    Schneider, L., Cammer, M., Lehman, J., Nielsen, S. K., Guerra, C. F., Veland, I. R., Stock, C., Hoffmann, E. K., Yoder, B. K., Schwab, A., Satir, P. & Christensen, Søren Tvorup, 2010, In: Cellular Physiology and Biochemistry. 25, 2-3, p. 279-92 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The primary cilium at a glance

    Satir, P., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2010, In: Journal of Cell Science. 123, Pt 4, p. 499-503 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions

    Awan, A., Oliveri, R. S., Jensen, P. L., Christensen, Søren Tvorup & tcg964, tcg964, 1 Jan 2010, In: Methods in Molecular Biology. 584, p. 195-210 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2011
  18. Published

    Characterization of an ex vivo femoral head model assessed by markers of bone and cartilage turnover

    Madsen, S. H., Goettrup, A. S., Thomsen, G., Christensen, Søren Tvorup, Schultz, N., Henriksen, K., Bay-Jensen, A. & Karsdal, M. A., 2011, In: Cartilage. 2, 3, p. 265-278 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

    Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glucocorticoids exert context-dependent effects on cells of the joint in vitro

    Madsen, S. H., Andreassen, K. V., Christensen, Søren Tvorup, Karsdal, M. A., Sverdrup, F. M., Bay-Jensen, A. & Henriksen, K., 2011, In: Steroids. 76, 13, p. 1474-82 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    In human granulosa cells from small antral follicles, androgen receptor mRNA and androgen levels in follicular fluid correlate with FSH receptor mRNA

    Nielsen, M. E., Rasmussen, I. A., Kristensen, S. G., Christensen, Søren Tvorup, Møllgård, Kjeld, Andersen, Elisabeth Anne Wreford, Byskov, A. G. S. & tcg964, tcg964, 2011, In: Molecular Human Reproduction. 17, 1, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2012
  23. Published

    Primary cilia and aberrant cell signaling in epithelial ovarian cancer

    Egeberg, D. L., Lethan, M., Manguso, R., Schneider, L., Awan, A., Jørgensen, T. S., Byskov, A. G., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Cilia. 1, 15, 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) signaling

    Christensen, Søren Tvorup, Clement, C. A., Satir, P. & Pedersen, Lotte Bang, 2012, In: Journal of Pathology. 226, 2, p. 172-184 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Regulating intraflagellar transport

    Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Nature Cell Biology. 14, 9, p. 904-906 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The ciliary cytoskeleton

    Pedersen, Lotte Bang, Schrøder, J. M., Satir, P. & Christensen, Søren Tvorup, 2012, In: Comprehensive Physiology. 2, 1, p. 779-803 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2013
  28. Published

    Analysis of primary cilia in directional cell migration in fibroblasts

    Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Proteomic analysis of human blastocoel fluid and blastocyst cells

    Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

    Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2014
  34. Published

    Cilia and coordination of signaling networks during heart development

    Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8

    Schou, K. B., Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2014, In: Cilia. 3, 6, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Proteomic analysis of bovine blastocoel fluid and blastocyst cells

    Jensen, P. L., Grøndahl, M. L., Beck, H. C., Petersen, J., Stroebech, L., Christensen, Søren Tvorup & tcg964, tcg964, 2014, In: Systems Biology in Reproductive Medicine. 60, 3, p. 127-135 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2015
  38. Published

    Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells

    Nygaard, M. B., Almstrup, Kristian, Lindbæk, L., Christensen, Søren Tvorup & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Evolutionary implications of localization of the signaling scaffold protein Parafusin to both cilia and the nucleus

    Satir, B. H., Wyroba, E., Liu, L., Lethan, M., Satir, P. & Christensen, Søren Tvorup, 2015, In: Cell Biology International. 39, 2, p. 136-145 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia

    Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    Ins and outs of GPCR signaling in primary cilia

    Schou, K. B., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2015, In: E M B O Reports. 16, 9, p. 1099-1113 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Kinesin-3 motor protein KIF13B localizes to centrosomes and primary cilia and regulates ciliary length and signaling

    Schou, K. B., Mogensen, J. B., Aleliunaite, A., Morthorst, Stine Kjær, Veland, I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., O3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2016
  46. Published

    Cilia and flagella

    Schmid, F. M., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2016, Encyclopedia of cell biology. Bradshaw, R. A. & Stahl, P. D. (eds.). 1 ed. Elsevier, Vol. 2. p. 660-676 17 p.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearchpeer-review

  47. Published

    Endocytic control of cellular signaling at the primary cilium

    Pedersen, Lotte Bang, Mogensen, J. B. & Christensen, Søren Tvorup, 2016, In: Trends in Biochemical Sciences. 41, 9, p. 784-797 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Immunofluorescence Microscopy and mRNA Analysis of Human Embryonic Stem Cells (hESCs) Including Primary Cilia Associated Signaling Pathways

    Vestergaard, M. L., Awan, A., Warzecha, C. B., Christensen, Søren Tvorup & tcg964, tcg964, 2016, Human Embryonic Stem Cell Protocols. Springer Science+Business Media, Vol. 1307. p. 123-140 (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  49. Published

    TGFβ1-induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner

    Labour, M., Riffault, M., Christensen, Søren Tvorup & Hoey, D. A., 2016, In: Scientific Reports. 6, 13 p., 35542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The intraflagellar transport machinery in ciliary signaling

    Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  51. 2017
  52. Published

    Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis

    Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling

    Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.

    Schou, K. B., Mogensen, J. B., Morthorst, Stine Kjær, Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 30 Jan 2017, In: Nature Communications. 8, 15 p., 14177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia

    Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation

    Vestergaard, M. L., Grubb, Søren, Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, Kirstine, Clausen, C., Christensen, Søren Tvorup, Møllgård, Kjeld & tcg964, tcg964, 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Hot spots of N2O emission move with the seasonally mobile oxic-anoxic interface in drained organic soils

    Lee, A. J., Winther, M. N., Priemé, Anders, Blunier, Thomas & Christensen, Søren Tvorup, 1 Dec 2017, In: Soil Biology & Biochemistry. 115, p. 178-186 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2018
  59. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

    Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4693