Søren Tvorup Christensen
Professor
Cell Biology and Physiology
Universitetsparken 13
2100 København Ø
- 2008
- Published
Effects of osmotic stress on the activity of MAPKs and PDGFR-beta-mediated signal transduction in NIH-3T3 fibroblasts
Nielsen, M., Christensen, Søren Tvorup & Hoffmann, E. K., 2008, In: American Journal of Physiology: Cell Physiology. 294, 4, p. C1046-55Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.
Schneider, L., Klausen, T. K., Stock, C., Mally, S., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Schwab, A., 2008, In: Pflügers Archiv: European Journal of Physiology. 455, 6, p. 1055-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery.
Kiprilov, E. N., Awan, A., Desprat, R., Velho, M., Clement, C. A., Byskov, A. G., tcg964, tcg964, Satir, P., Bouhassira, E. E., Christensen, Søren Tvorup & Hirsch, R. E., 2008, In: Journal of Cell Biology. 180, 5, p. 897-904 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure and function of mammalian cilia
Satir, P. & Christensen, Søren Tvorup, 2008, In: Histochemistry and Cell Biology. 129, 6, p. 687-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Primary cilia and signaling pathways in mammalian development, health and disease
Veland, I. R., Awan, A., Pedersen, Lotte Bang, Yoder, B. K. & Christensen, Søren Tvorup, 2009, In: NEPHRON PHYSIOLOGY. 111, 3, p. p39-53Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium
Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation
Clement, C. A., Kristensen, S. G., Møllgård, Kjeld, Pazour, G. J., Yoder, B. K., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, In: Journal of Cell Science. 122, Pt 17, p. 3070-82 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using Nucleofection of siRNA Constructs for Knockdown of Primary Cilia in P19.CL6 Cancer Stem Cell Differentiation into Cardiomyocytes
Clement, C. A., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 181-197Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Using quantitative PCR to Identify Kinesin-3 Genes that are Upregulated During Growth Arrest in Mouse NIH3T3 Cells
Thorsteinsson, R. I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2009, Primary Cilia. Sloboda, R. D. (ed.). Elsevier, p. 66-86 21 p. (Methods in Cell Biology, Vol. 94).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Using quantitative PCR to Identify Kinesin-3 Genes that are Upregulated During Growth Arrest in MouseNIH3T3 Cells
Thorsteinsson, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 66-86Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 2010
- Published
Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts
Schneider, L., Cammer, M., Lehman, J., Nielsen, S. K., Guerra, C. F., Veland, I. R., Stock, C., Hoffmann, E. K., Yoder, B. K., Schwab, A., Satir, P. & Christensen, Søren Tvorup, 2010, In: Cellular Physiology and Biochemistry. 25, 2-3, p. 279-92 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The primary cilium at a glance
Satir, P., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2010, In: Journal of Cell Science. 123, Pt 4, p. 499-503 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions
Awan, A., Oliveri, R. S., Jensen, P. L., Christensen, Søren Tvorup & tcg964, tcg964, 1 Jan 2010, In: Methods in Molecular Biology. 584, p. 195-210 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Characterization of an ex vivo femoral head model assessed by markers of bone and cartilage turnover
Madsen, S. H., Goettrup, A. S., Thomsen, G., Christensen, Søren Tvorup, Schultz, N., Henriksen, K., Bay-Jensen, A. & Karsdal, M. A., 2011, In: Cartilage. 2, 3, p. 265-278 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms
Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucocorticoids exert context-dependent effects on cells of the joint in vitro
Madsen, S. H., Andreassen, K. V., Christensen, Søren Tvorup, Karsdal, M. A., Sverdrup, F. M., Bay-Jensen, A. & Henriksen, K., 2011, In: Steroids. 76, 13, p. 1474-82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In human granulosa cells from small antral follicles, androgen receptor mRNA and androgen levels in follicular fluid correlate with FSH receptor mRNA
Nielsen, M. E., Rasmussen, I. A., Kristensen, S. G., Christensen, Søren Tvorup, Møllgård, Kjeld, Andersen, Elisabeth Anne Wreford, Byskov, A. G. S. & tcg964, tcg964, 2011, In: Molecular Human Reproduction. 17, 1, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Primary cilia and aberrant cell signaling in epithelial ovarian cancer
Egeberg, D. L., Lethan, M., Manguso, R., Schneider, L., Awan, A., Jørgensen, T. S., Byskov, A. G., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Cilia. 1, 15, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary cilia and coordination of receptor tyrosine kinase (RTK) signaling
Christensen, Søren Tvorup, Clement, C. A., Satir, P. & Pedersen, Lotte Bang, 2012, In: Journal of Pathology. 226, 2, p. 172-184 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulating intraflagellar transport
Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Nature Cell Biology. 14, 9, p. 904-906 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ciliary cytoskeleton
Pedersen, Lotte Bang, Schrøder, J. M., Satir, P. & Christensen, Søren Tvorup, 2012, In: Comprehensive Physiology. 2, 1, p. 779-803 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Analysis of primary cilia in directional cell migration in fibroblasts
Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration
Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways
Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of human blastocoel fluid and blastocyst cells
Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium
Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Cilia and coordination of signaling networks during heart development
Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8
Schou, K. B., Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2014, In: Cilia. 3, 6, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of bovine blastocoel fluid and blastocyst cells
Jensen, P. L., Grøndahl, M. L., Beck, H. C., Petersen, J., Stroebech, L., Christensen, Søren Tvorup & tcg964, tcg964, 2014, In: Systems Biology in Reproductive Medicine. 60, 3, p. 127-135 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells
Nygaard, M. B., Almstrup, Kristian, Lindbæk, L., Christensen, Søren Tvorup & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coordination of TGFβ/BMP signaling is associated with the primary cilium
Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Evolutionary implications of localization of the signaling scaffold protein Parafusin to both cilia and the nucleus
Satir, B. H., Wyroba, E., Liu, L., Lethan, M., Satir, P. & Christensen, Søren Tvorup, 2015, In: Cell Biology International. 39, 2, p. 136-145 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia
Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Ins and outs of GPCR signaling in primary cilia
Schou, K. B., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2015, In: E M B O Reports. 16, 9, p. 1099-1113 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Kinesin-3 motor protein KIF13B localizes to centrosomes and primary cilia and regulates ciliary length and signaling
Schou, K. B., Mogensen, J. B., Aleliunaite, A., Morthorst, Stine Kjær, Veland, I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., O3.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism
Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Cilia and flagella
Schmid, F. M., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2016, Encyclopedia of cell biology. Bradshaw, R. A. & Stahl, P. D. (eds.). 1 ed. Elsevier, Vol. 2. p. 660-676 17 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research › peer-review
- Published
Endocytic control of cellular signaling at the primary cilium
Pedersen, Lotte Bang, Mogensen, J. B. & Christensen, Søren Tvorup, 2016, In: Trends in Biochemical Sciences. 41, 9, p. 784-797 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Immunofluorescence Microscopy and mRNA Analysis of Human Embryonic Stem Cells (hESCs) Including Primary Cilia Associated Signaling Pathways
Vestergaard, M. L., Awan, A., Warzecha, C. B., Christensen, Søren Tvorup & tcg964, tcg964, 2016, Human Embryonic Stem Cell Protocols. Springer Science+Business Media, Vol. 1307. p. 123-140 (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
TGFβ1-induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner
Labour, M., Riffault, M., Christensen, Søren Tvorup & Hoey, D. A., 2016, In: Scientific Reports. 6, 13 p., 35542.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intraflagellar transport machinery in ciliary signaling
Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.Research output: Contribution to journal › Review › Research › peer-review
- 2017
- Published
Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis
Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling
Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
Schou, K. B., Mogensen, J. B., Morthorst, Stine Kjær, Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 30 Jan 2017, In: Nature Communications. 8, 15 p., 14177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia
Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation
Vestergaard, M. L., Grubb, Søren, Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, Kirstine, Clausen, C., Christensen, Søren Tvorup, Møllgård, Kjeld & tcg964, tcg964, 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hot spots of N2O emission move with the seasonally mobile oxic-anoxic interface in drained organic soils
Lee, A. J., Winther, M. N., Priemé, Anders, Blunier, Thomas & Christensen, Søren Tvorup, 1 Dec 2017, In: Soil Biology & Biochemistry. 115, p. 178-186 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium
Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Challenges for the sustainability of university-run biobanks
Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases
Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4693
Most downloads
-
1877
downloads
Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1771
downloads
Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1263
downloads
Primary cilia and aberrant cell signaling in epithelial ovarian cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published