Glucocorticoids exert context-dependent effects on cells of the joint in vitro
Research output: Contribution to journal › Journal article › Research › peer-review
Glucocorticoids are known to attenuate bone formation in vivo leading to decreased bone volume and increased risk of fractures, whereas effects on the joint tissue are less characterized. However, glucocorticoids appear to have a reducing effect on inflammation and pain in osteoarthritis. This study aimed at characterizing the effect of glucocorticoids on chondrocytes, osteoclasts, and osteoblasts.
| Original language | English |
|---|---|
| Journal | Steroids |
| Volume | 76 |
| Issue number | 13 |
| Pages (from-to) | 1474-82 |
| Number of pages | 9 |
| ISSN | 0039-128X |
| DOIs | |
| Publication status | Published - 2011 |
- Animals, Antigens, CD14, Bone Remodeling, Cartilage, Articular, Cattle, Cell Line, Cell Survival, Cytokines, Dexamethasone, Female, Femur Head, Glucocorticoids, Humans, Joints, Mice, Organ Specificity, Osteoblasts, Osteoclasts, Prednisolone
Research areas
ID: 37661090