Charlotte O'Shea

Charlotte O'Shea

Academic employee FU


  1. 2024
  2. Published

    Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants

    Theisen, Frederik Friis, Prestel, Andreas, Elkjær, Steffie Martina H, Leurs, Y. H. A., Morffy, N., Strader, L. C., O'Shea, Charlotte, Teilum, Kaare, Kragelund, Birthe Brandt & Skriver, Karen, 2024, In: Nature Communications. 15, 1, 13 p., 592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2022
  4. Published

    Germin like protein genes exhibit modular expression during salt and drought stress in elite rice cultivars

    Anum, J., O'Shea, Charlotte, Hyder, M. Z., Farrukh, S., Skriver, Karen, Malik, S. I. & Yasmin, T., 2022, In: Molecular Biology Reports. 49, 1, p. 293-302 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Increasing protein stability by inferring substitution effects from high-throughput experiments

    Norrild, R. K., Johansson, Kristoffer Enøe, O'Shea, Charlotte, Morth, J. P., Lindorff-Larsen, Kresten & Winther, Jakob R., 2022, In: Cell Reports Methods. 2, 11, 11 p., 100333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2021
  7. Published

    Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold

    Marin, Frederikke Isa, Johansson, Kristoffer Enøe, O'Shea, Charlotte, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: The Journal of Physical Chemistry B. 125, 40, p. 11141-11149

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    Quantification of Conformational Entropy Unravels Effect of Disordered Flanking Region in Coupled Folding and Binding

    Theisen, Frederik Friis, Staby, L., Tidemand, Frederik Grønbæk, O'Shea, Charlotte, Prestel, Andreas, Willemoës, Martin, Kragelund, Birthe Brandt & Skriver, Karen, 2021, In: Journal of the American Chemical Society. 143, 36, p. 14540-14550 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Improving folding properties of computationally designed proteins

    Bjerre, B., Nissen, J., Madsen, M., Kamarauskaite, J., Norrild, R. K., Holm, Peter Christoffer, Nordentoft, M. K., O'Shea, Charlotte, Willemoës, Martin, Johansson, Kristoffer Enøe & Winther, Jakob R., 13 Dec 2019, In: Protein Engineering Design and Selection (Print). 32, 3, p. 145-151 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome

    Christensen, L. F., Staby, L., Bugge, K., O'Shea, Charlotte, Kragelund, Birthe Brandt & Skriver, Karen, 2019, In: Scientific Reports. 9, 15 p., 18927.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Structure of radical-induced cell death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks

    Bugge, K. Ø., Staby, L., Kemplen, K. R., O'Shea, Charlotte, Bendsen, S. K., Jensen, M. K., Olsen, Johan Gotthardt, Skriver, Karen & Kragelund, Birthe Brandt, 2018, In: Structure. 26, 5, p. 734-746 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    SLiMming the fuzz in gene-regulating interactomes

    Staby, L., O'Shea, Charlotte, Kragelund, Birthe Brandt & Skriver, Karen, 7 Nov 2017, 1 p.

    Research output: Other contributionNet publication - Internet publicationResearch

  17. Published

    Involvement of WRKY, MYB and DOF DNA-binding proteins in interaction with a rice germin-like protein gene promoter

    Deeba, F., Sultana, T., Mahmood, T., O'Shea, Charlotte, Skriver, Karen & Naqvi, S. M. S., Aug 2017, In: Acta Physiologiae Plantarum. 39, 10 p., 189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Eukaryotic transcription factors: paradigms of protein intrinsic disorder

    Staby, L., O'Shea, Charlotte, Willemoës, Martin, Theisen, F., Kragelund, Birthe Brandt & Skriver, Karen, 12 Jul 2017, In: Biochemical Journal. 474, 15, p. 2509-2532 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1

    O'Shea, Charlotte, Staby, L., Bendsen, S. K., Tidemand, Frederik Grønbæk, Redsted, A., Willemoës, Martin, Kragelund, Birthe Brandt & Skriver, Karen, 13 Jan 2017, In: Journal of Biological Chemistry. 292, 2, p. 512-527 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2016
  21. Published

    Barley plants over-expressing the NAC transcription factor gene HvNAC005 show stunting and delay in development combined with early senescence

    Christiansen, M. W., Matthewman, C., Podzimska-Sroka, D. A., O'Shea, Charlotte, Lindemose, Søren, Møllegaard, Niels Erik, Holme, I. B., Hebelstrup, K., Skriver, Karen & Gregersen, P. L., 2016, In: Journal of Experimental Botany. 67, 17, p. 5259-5273 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2015
  23. Published

    NAC transcription factors in senescence: from molecular structure to function in crops

    Podzimska-Sroka, D., O'Shea, Charlotte, Gregersen, P. L. & Skriver, Karen, 2015, In: Plants. 4, 3, p. 412-448 37 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Protein intrinsic disorder in Arabidopsis NAC transcription factors: transcriptional activation by ANAC013 and ANAC046 and their interactions with RCD1

    O'Shea, Charlotte, Jensen, M. K., Stender, E. G. P., Kragelund, Birthe Brandt, Willemoës, Martin & Skriver, Karen, 2015, In: Biochemical Journal. 465, 2, p. 281-294 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Subgroup-specific intrinsic disorder profiles of arabidopsis NAC transcription factors: identification of functional hotspots

    Stender, E. G., O'Shea, Charlotte & Skriver, Karen, 2015, In: Plant Signalling & Behavior. 10, 6, 4 p., e1010967.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2014
  27. Published

    A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana

    Lindemose, Søren, Jensen, M. K., Van de Velde, J., O'Shea, Charlotte, Heyndrickx, K. S., Workman, C., Vandepoele, K., Skriver, Karen & De Masi, F., 2014, In: Nucleic Acids Research. 42, 12, p. 7681-7693 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    NAC Transcription Factors in Stress Responses and Senescence: Importance of Intrinsic Disorder and DNA Binding

    O'Shea, Charlotte, 2014, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  29. 2013
  30. Published

    Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin

    Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Structure, function and networks of transcription factors involved in abiotic stress responses

    Lindemose, Søren, O'Shea, Charlotte, Jensen, M. K. & Skriver, Karen, 2013, In: International Journal of Molecular Sciences (Online). 14, 3, p. 5842-78 37 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2012
  33. Published

    The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

    Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2011
  35. Published

    Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

    Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2010
  37. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The Arabidopsis thaliana NAC transcription factor family: structure-function relationships and determinants of ANAC019 stress signalling

    Jensen, M. K., Kjaersgaard, T., Nielsen, M. M., Galberg, P., Petersen, K., O'Shea, Charlotte & Skriver, Karen, 1 Mar 2010, In: Biochemical Journal. 426, 2, p. 183-96 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2008
  40. Published

    Biochemical function of typical and variant Arabidopsis thaliana U-box E3 ubiquitin-protein ligases

    Wiborg, J., O'Shea, Charlotte & Skriver, Karen, 2008, In: Biochemical Journal. 413, 3, p. 447-457 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2006
  42. Published

    Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif.

    Jensen, G. A., Andersen, O. M., Bonvin, A. M. J. J., Bjerrum-Bohr, I., Etzerodt, M., Thøgersen, H. C., O'Shea, Charlotte, Poulsen, F. M. & Kragelund, Birthe Brandt, 2006, In: Journal of Molecular Biology. 362, 4, p. 700-16 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 336979689