Henriette Pilegaard

Henriette Pilegaard

Professor

ORCID: 0000-0002-1071-0327

Publication year:
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1 - 100 out of 186Page size: 100
  1. 2023
  2. Published

    Hepatic PGC-1α has minor regulatory effect on the liver transcriptome and metabolome during high fat high fructose diet and exercise training

    Rasmussen, M. K., Thøgersen, R., Horsbøl Lindholm, P., Bertram, H. C. & Pilegaard, Henriette, 2023, In: Gene. 851, 14 p., 147039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

    Jørgensen, Stine Ringholm, Gudiksen, Anders, Halling, Jens Frey, Qoqaj, A., Rasmussen, P. M., Prats Gavalda, Clara, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Muscle PGC-1α modulates hepatic mitophagy regulation during aging

    Christensen, N. M., Jørgensen, Stine Ringholm, Buch, B. T., Gudiksen, Anders, Halling, Jens Frey & Pilegaard, Henriette, 2023, In: Experimental Gerontology. 172, 9 p., 112046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes

    Maurer, J., Zhao, X., Irmler, M., Gudiksen, Anders, Pilmark, N. S., Li, Q., Goj, T., Beckers, J., Hrabě De Angelis, M., Birkenfeld, A. L., Peter, A., Lehmann, R., Pilegaard, Henriette, Karstoft, Kristian, Xu, G. & Weigert, C., 2023, In: American Journal of Physiology: Cell Physiology. 325, 4, p. C1131-C1143 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue

    Gudiksen, Anders, Qoqaj, A., Jørgensen, Stine Ringholm, Wojtaszewski, Jørgen F P, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2022, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 77, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Beta2-agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men

    Hostrup, Morten, Knudsen, Jakob Grunnet, Maag Kristensen, C., Jessen, Søren Kaare, Pilegaard, Henriette & Bangsbo, Jens, 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 7, p. 1099-1108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

    Plomgaard, Peter Stendahl, Hansen, J. S., Townsend, L. K., Gudiksen, Anders, Secher, Niels H., Clemmesen, J. O., Støving, R. K., Goetze, Jens P. , Wright, D. C. & Pilegaard, Henriette, 2022, In: Frontiers in Endocrinology. 13, 1037948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

    Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9

    Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice

    Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2021
  15. Published

    High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells

    Hansen, Camilla Collin, Olsen, K., Pilegaard, Henriette, Bangsbo, Jens, Gliemann, Lasse & Hellsten, Ylva, 2021, In: Physiological Reports. 9, 14, 17 p., e14855.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner

    Buch, B. T., Halling, Jens Frey, Jørgensen, Stine Ringholm, Gudiksen, Anders, Kjøbsted, Rasmus, Olsen, M. A., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2020, In: F A S E B Journal. 34, 6, p. 8653-8670

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Exercise: from physiology to bedside to physiology

    Han, J., Neufer, D. & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 135

    Research output: Contribution to journal › Editorial › Research › peer-review

  20. Published

    Hepatic PGC-1α is not essential for fasting-induced cytochrome p450 regulation in mouse liver

    Thøgersen, R., Maag Kristensen, C., Olsen, M. A., Bertram, H. C., Pilegaard, Henriette & Rasmussen, M. K., 2020, In: Biochemical Pharmacology. 172, 7 p., 113736.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Impact of skeletal muscle IL-6 on subcutaneous and visceral adipose tissue metabolism immediately after high- and moderate-intensity exercises

    Bertholdt, L., Gudiksen, Anders, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 217-233 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2x2 factorial, randomised, crossover study in human individuals

    Hjelholt, A. J., Charidemou, E., Griffin, J. L., Pedersen, S. B., Gudiksen, Anders, Pilegaard, Henriette, Jessen, N., Møller, N. & Jørgensen, J. O. L., 2020, In: Diabetologia. 63, 12, p. 2641-2653 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    PGC-1α-mediated regulation of mitochondrial function and physiological implications

    Halling, Jens Frey & Pilegaard, Henriette, 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. 2019
  26. Published

    Exercise physiology: future opportunities and challenges

    Han, J., Neufer, D. & Pilegaard, Henriette, 2019, In: Pflügers Archiv - European Journal of Physiology. 471, 3, p. 381 1 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Inclusion of sprints in moderate intensity continuous training leads to muscle oxidative adaptations in trained individuals

    Gunnarsson, T. G. P., Brandt, N., Fiorenza, Matteo, Hostrup, Morten, Pilegaard, Henriette & Bangsbo, Jens, 2019, In: Physiological Reports. 7, 4, 15 p., e13976.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

    Sailani, M. R., Halling, Jens Frey, Møller, H. D., Lee, H., Plomgaard, Peter Stendahl, Pilegaard, Henriette, Snyder, M. P. & Regenberg, Birgitte, 2019, In: Scientific Reports. 9, p. 1-11 3272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training

    Halling, Jens Frey, Jessen, H., Nøhr-Meldgaard, J., Buch, B. T., Christensen, N. M., Gudiksen, Anders, Jørgensen, Stine Ringholm, Neufer, P. D., Prats Gavalda, Clara & Pilegaard, Henriette, 2019, In: American journal of physiology. Endocrinology and metabolism. 317, 3, p. E513-E525

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

    Høgild, M. L., Gudiksen, Anders, Pilegaard, Henriette, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jørgensen, J. O. L. & Jessen, N., 2019, In: Physiological Reports. 7, 21, 15 p., e14285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2018
  32. Published

    Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

    Møller, H. D., Mohiyuddin, M., Prada Luengo, Inigo, Sailani, M. R., Halling, Jens Frey, Plomgaard, Peter Stendahl, Maretty, L., Hansen, Anders Johannes, Snyder, M. P., Pilegaard, Henriette, Lam, H. Y. K. & Regenberg, Birgitte, 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Beta2-adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men

    Hostrup, Morten, Reitelseder, S., Jessen, Søren Kaare, Kalsen, A., Nyberg, M. P., Egelund, J., Kreiberg, M., Maag Kristensen, C., Thomassen, Martin, Pilegaard, Henriette, Backer, Vibeke, Jacobson, G. A., Holm, L. & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 17, p. 4121-4139 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

    Rasmussen, M. K., Bertholdt, L., Gudiksen, Anders, Pilegaard, Henriette & Knudsen, Jakob Grunnet, 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Muscle PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Maag Kristensen, C., Jessen, H., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Acta Physiologica. 224, 4, p. 1-17 e13158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2017
  49. Published

    Skeletal muscle IL-6 regulates muscle substrate utilization and adipose tissue metabolism during recovery from an acute bout of exercise

    Knudsen, Jakob Grunnet, Gudiksen, Anders, Bertholdt, L., Overby, P., Villesen, I., Schwartz, C. L. & Pilegaard, Henriette, 18 Dec 2017, In: PLoS ONE. 12, 12, 19 p., e0189301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PGC-1α in aging and lifelong exercise training-mediated regulation of UPR in mouse liver

    Maag Kristensen, C., Brandt, C. T., Jørgensen, Stine Ringholm & Pilegaard, Henriette, Nov 2017, In: Experimental Gerontology. 98, p. 124-133 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Olesen, J., Prats Gavalda, Clara & Pilegaard, Henriette, 1 Oct 2017, In: Experimental Gerontology. 96, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Autophagy-dependent beneficial effects of exercise

    Halling, Jens Frey & Pilegaard, Henriette, Aug 2017, In: Cold Spring Harbor Perspectives in Medicine. 7, 8, a029777.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders & Pilegaard, Henriette, 10 Apr 2017, In: Physiological Reports. 5, 7, 15 p., e13222.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Lack of skeletal muscle IL-6 influences hepatic glucose metabolism in mice during prolonged exercise

    Bertholdt, L., Gudiksen, Anders, Schwartz, C. L., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 7 Apr 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 4, p. R626-R636 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Vingborg, M. B., Hansen, H. W., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E204-E214 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Effects of training status on PDH regulation in human skeletal muscle during exercise

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Tybirk, J., Plomgaard, Peter Stendahl, Bangsbo, Jens & Pilegaard, Henriette, 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 12, p. 1615-1630 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Opposite regulation of insulin sensitivity by dietary lipid versus carbohydrate excess

    Lundsgaard, Anne-Marie, Sjøberg, K. A., Høeg, L. D., Jeppesen, J., Jordy, A. B., Serup, A. K. L., Fritzen, Andreas Mæchel, Pilegaard, Henriette, Myrmel, L. S., Madsen, L., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2017, In: Diabetes. 66, 10, p. 2583-2595 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle

    Brandt, N., Dethlefsen, M. M., Bangsbo, Jens & Pilegaard, Henriette, 2017, In: P L o S One. 12, 10, 21 p., e0185993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. 2016
  60. Published

    Combined speed endurance and endurance exercise amplify the exercise-induced PGC-1α and PDK4 mRNA response in trained human muscle

    Skovgaard, C., Brandt, N., Pilegaard, Henriette & Bangsbo, Jens, 2016, In: Physiological Reports. 4, 14, 14 p., e12864.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Impact of adrenaline and metabolic stress on exercise-induced intracellular signaling and PGC-1α mRNA response in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Hostrup, Morten, Tybirk, J., Nybo, Lars, Pilegaard, Henriette & Bangsbo, Jens, 2016, In: Physiological Reports. 4, 14, 13 p., e12844.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Lack of skeletal muscle IL-6 affects pyruvate dehydrogenase activity at rest and during prolonged exercise

    Gudiksen, Anders, Schwartz, C. L., Bertholdt, L., Joensen, E., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 2016, In: P L o S One. 11, 6, 17 p., e0156460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Nielsen, M. M., Overby, P. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 3, 11 p., e12698.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training

    Knudsen, Jakob Grunnet, Joensen, E., Bertholdt, L., Jessen, H., van Hauen, L., Hidalgo, J. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 9, 9 p., e12788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. 2015
  66. Published

    5´AMP activated protein kinase α2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jeppesen, J., Christiansen, M. L. B., Biensø, R. S., Dyck, J. R. B., Pilegaard, Henriette & Kiens, Bente, 2015, In: Journal of Physiology. 593, 21, p. 4765-4780 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle

    Fentz, J., Kjøbsted, Rasmus, Maag Kristensen, C., Hingst, J. R., Birk, Jesper Bratz, Gudiksen, Anders, Foretz, M., Schjerling, Peter, Viollet, B., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 309, 11, p. E900-E914 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle

    Edge, J., Muendel, T., Pilegaard, Henriette, Hawke, E., Leikis, M., Lopez-Villalobos, N., Oliveira, R. S. F. & Bishop, D. J., 2015, In: P L o S One. 10, 12, 14 p., e0141317.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Effects of exercise training on regulation of skeletal muscle glucose metabolism in elderly men

    Biensø, R. S., Olesen, J., Gliemann, Lasse, Schmidt, J. F., Matzen, M. S., Wojtaszewski, Jørgen F P, Hellsten, Ylva & Pilegaard, Henriette, 2015, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 70, 7, p. 866-872 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Exercise-induced AMPK and pyruvate dehydrogenase regulation is maintained during short-term low-grade inflammation

    Biensø, R. S., Olesen, J., van Hauen, L., Meinertz, S., Halling, J. F., Gliemann, Lasse, Plomgaard, P. & Pilegaard, Henriette, 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 2, p. 341-350 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Exercise-induced regulation of key factors in substrate choice and gluconeogenesis in mouse liver

    Knudsen, Jakob Grunnet, Biensø, R. S., Hassing, H. A., Jakobsen, A. H. & Pilegaard, Henriette, 2015, In: Molecular and Cellular Biochemistry. 403, 1-2, p. 209-217 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Impact of training status on LPS-induced acute inflammation in humans

    Olesen, J., Biensø, R. S., Meinertz, S., van Hauen, L., Rasmussen, S. M., Gliemann, Lasse, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2015, In: Journal of Applied Physiology. 118, 7, p. 818-829 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    New Nordic Diet induced weight loss is accompanied by changes in metabolism and AMPK signalling in adipose tissue

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jordy, A. B., Poulsen, S. K., Stender, Steen, Pilegaard, Henriette, Astrup, A., Larsen, T. M., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 9, p. 3509-3519 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

    Knudsen, Jakob Grunnet, Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, Henriette, 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. 2014
  76. Published

    Effects of IL-6 on pyruvate dehydrogenase regulation in mouse skeletal muscle

    Biensø, R. S., Knudsen, Jakob Grunnet, Brandt, N., Pedersen, Per Amstrup & Pilegaard, Henriette, 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 8, p. 1647-1657 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men

    Olesen, J., Gliemann, Lasse, Biensøe, R. S., Schmidt, J. F., Hellsten, Ylva & Pilegaard, Henriette, 2014, In: Journal of Physiology. 592, 8, p. 1873-1886 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes 2012;61:1090-1099

    Biensø, R. S., Ringholm, S., Kiilerich, K., Aachmann-Andersen, N., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2014, In: Diabetes. 63, 9, 1 p., 3159.

    Research output: Contribution to journal › Comment/debate › Research

  79. Published

    Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity

    Nellemann, B., Vendelbo, M. H., Nielsen, Thomas Svava, Bak, A. M., Høgild, M., Pedersen, S. B., Biensø, R. S., Pilegaard, Henriette, Møller, N., Jessen, N. & Jørgensen, J. O. L., 2014, In: Acta Physiologica. 210, 2, p. 392-402 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Insulin sensitivity is independent of lipid binding protein trafficking at the plasma membrane in human skeletal muscle: Effect of a 3-day, high-fat diet

    Jordy, A. B., Serup, A. K., Karstoft, K., Pilegaard, Henriette, Kiens, Bente & Jeppesen, J. F., 2014, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 307, 9, p. R1136-R1145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Leptin signaling in skeletal muscle after bed rest in healthy humans

    Guerra, B., Ponce-Gonzalez, J. G., Morales-Alamo, D., Guadalupe-Grau, A., Kiilerich, K., Fuentes, T., Jørgensen, Stine Ringholm, Biensø, R. S., Santana, A., Lundby, C., Pilegaard, Henriette & Calbet, J. A. L., 2014, In: European Journal of Applied Physiology. 114, 2, p. 345-357 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock

    Dyar, K. A., Ciciliot, S., Wright, L. E., Biensø, R. S., Tagliazucchi, G. M., Patel, V. R., Forcato, M., Paz, M. I. P., Gudiksen, Anders, Solagna, F., Albiero, M., Moretti, I., Eckel-Mahan, K. L., Baldi, P., Sassone-Corsi, P., Rizzuto, R., Bicciato, S., Pilegaard, Henriette, Blaauw, B. & Schiaffino, S., 2014, In: Molecular Metabolism. 3, 1, p. 29-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Reply from Lasse Gliemann, Jesper Olesen, Rasmus Sjørup Biensø, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Olesen, J., Biensø, R. S., Mortensen, S. P., Nyberg, M. P., Schmidt, J. F., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 3, p. 553 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  84. Published

    Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue

    Knudsen, Jakob Grunnet, Murholm, M., Carey, A. L., Biensø, R. S., Basse, A. L., Allen, T. L., Hidalgo, J., Kingwell, B. A., Febbraio, M. A., Hansen, Jacob B. & Pilegaard, Henriette, 2014, In: P L o S One. 9, 1, 8 p., e84910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. 2013
  86. Published

    AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle

    Brandauer, J., Vienberg, S. G., Andersen, M. A., Jørgensen, Stine Ringholm, Risis, S., Larsen, P., Kristensen, Jonas Møller, Frøsig, C., Leick, L., Fentz, J., Jørgensen, S. B., Kiens, Bente, Wojtaszewski, Jørgen F P, Richter, Erik A., Zierath, Juleen R, Goodyear, L. J., Pilegaard, Henriette & Treebak, Jonas Thue, 2013, In: Journal of Physiology. 591, p. 5207-5220 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Both short intense and prolonged moderate in vitro stimulation reduce the mRNA expression of calcium-regulatory proteins in rat skeletal muscle

    Mänttäri, S., Ørtenblad, N., Madsen, K. & Pilegaard, Henriette, 2013, In: Molecular and Cellular Biochemistry. 373, 1-2, p. 171-178 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown and increased IL-6 release

    Bach, E., Nielsen, R. R., Vendelbo, M., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, Henriette, Biensøe, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Diabetes. 62, 12, p. 4023-4029

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg

    Buhl, M., Bosnjak, E., Vendelbo, M. H., Gjedsted, J., Nielsen, R. R., Hafstrøm, T. K., Vestergaard, E. T., Jessen, N., Tønnesen, E., Møller, A. B., Pedersen, S. B., Pilegaard, Henriette, Biensø, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 5, p. 2090-2099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Effect of birth weight and 12 weeks of exercise training on exercise-induced AMPK signaling in human skeletal muscle

    Mortensen, B., Hingst, J. R., Frederiksen, N., Hansen, R. W. W., Christiansen, C. S., Iversen, N., Friedrichsen, M., Birk, Jesper Bratz, Pilegaard, Henriette, Hellsten, Ylva, Vaag, Allan & Wojtaszewski, Jørgen F P, 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 12, p. E1379-E1390 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice: impact of PGC-1α

    Jørgensen, Stine Ringholm, Olesen, J., Pedersen, J. T., Brandt, C. T., Halling, J. F., Hellsten, Ylva, Prats Gavalda, Clara & Pilegaard, Henriette, 2013, In: Experimental Gerontology. 48, 11, p. 1311-1318 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Exercise training and work task induced metabolic and stress-related mRNA and protein responses in myalgic muscles

    Sjøgaard, G., Zebis, M. K., Kiilerich, K., Saltin, B. & Pilegaard, Henriette, 2013, In: Journal of Biomedicine and Biotechnology. 2013, 12 p., 984523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice

    Lindegaard, Birgitte, Matthews, V. B., Brandt, C., Hojman, P., Allen, T. L., Estevez, E., Watt, M. J., Bruce, C. R., Mortensen, Ole Hartvig, Syberg, S., Rudnicka, C., Abildgaard, J., Pilegaard, Henriette, Hidalgo, J., Ditlevsen, Susanne, Alsted, T. J., Madsen, A. N., Pedersen, Bente Klarlund & Febbraio, M. A., 2013, In: Diabetes. 62, 9, p. 3064-3074 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Menopause is associated with decreased whole body fat oxidation during exercise

    Abildgaard, J., Pedersen, Anette Tønnes, Green, C. J., Majlund Harder-Lauridsen, N., Solomon, T. P., Thomsen, C., Juul, A., Pedersen, M., Pedersen, J. T., Mortensen, Ole Hartvig, Pilegaard, Henriette, Pedersen, Bente Klarlund & Lindegaard, B., 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 11, p. E1227-E1236 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue.

    Jørgensen, Stine Ringholm, Knudsen, Jakob Grunnet, Leick, L., Lundgaard, A., Munk Nielsen, M. & Pilegaard, Henriette, 2013, In: PloS one. 8, 5, p. 1-6 6 p., e64123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Reply from Lasse Gliemann, Jakob Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Schmidt, J., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5253 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  97. Published

    Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

    Gliemann, Lasse, Schmidt, J. F., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M. P., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5047-5059 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation

    Olesen, J., Jørgensen, Stine Ringholm, Nielsen, M. M., Brandt, C. T., Pedersen, J. T., Halling, J. F., Goodyear, L. J. & Pilegaard, Henriette, 2013, In: Experimental Gerontology. 48, 11, p. 1274-1284 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle

    Høier, B., Prats Gavalda, Clara, Qvortrup, Klaus, Pilegaard, Henriette, Bangsbo, Jens & Hellsten, Ylva, 2013, In: F A S E B Journal. 27, 9, p. 3496-3504 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. 2012
  101. Published

    Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects

    Christensen, B., Lundby, C., Jessen, N., Nielsen, Thomas Svava, Vestergaard, P. F., Møller, N., Pilegaard, Henriette, Pedersen, S. B., Kopchick, J. J. & Jørgensen, J. O. L., 2012, In: P L o S One. 7, 2, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance

    Biensø, R. S., Jørgensen, Stine Ringholm, Kiilerich, K., Aachmann-Andersen, N. J., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2012, In: Diabetes. 61, 5, p. 1090-1099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    IL-6 regulates exercise and training-induced adaptations in subcutaneous adipose tissue in mice

    Brandt, C., Jakobsen, A. H., Hassing, H. A., Olesen, Jes, Iversen, N., Kristensen, Jonas Møller, Hojman, P., Wojtaszewski, Jørgen F P, Hidalgo, J. & Pilegaard, Henriette, 2012, In: Acta Physiologica (Print). 205, 2, p. 224-235 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Role of vitamin C and E supplementation on IL-6 in response to training

    Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Skeletal muscle PGC-1a is required for maintaining an acute LPS-induced TNFa response

    Olesen, J., Larsson, S., Iversen, N., Yousafzai, S., Hellsten, Ylva & Pilegaard, Henriette, 2012, In: P L o S One. 7, 2, p. e32222 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. 2011
  107. Published

    Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle

    Jørgensen, Stine Ringholm, Biensø, R. S., Kiilerich, K., Guadalupe-Grau, A., Aachmann-Andersen, N. J., Saltin, B., Plomgaard, Peter Stendahl, Lundby, C., Wojtaszewski, Jørgen F P, Calbet, J. A. & Pilegaard, Henriette, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 301, 4, p. E649-E658 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Exercise-induced liver chemokine CXCL-1 expression is linked to muscle-derived interleukin-6 expression

    Pedersen, L., Pilegaard, Henriette, Hansen, J., Brandt, C., Adser, H., Hidalgo, J., Olesen, J., Pedersen, Bente Klarlund & Hojman, P., 2011, In: Journal of Physiology. 589, 6, p. 1409-20 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest

    Kiilerich, K., Jørgensen, Stine Ringholm, Biensø, R. S., Fisher, J. P., Iversen, N., van Hall, Gerrit, Wojtaszewski, Jørgen F P, Saltin, B., Lundby, C., Calbet, J. A. L. & Pilegaard, Henriette, 2011, In: Journal of Applied Physiology. 111, 3, p. 751-757 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Fatty acid composition in organs.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  111. Published

    Fatty acid composition in red blood cells.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  112. Published

    Fatty acid composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  113. Published

    Interleukin-6 modifies mRNA expression in mouse skeletal muscle

    Hassing, H. A., Wojtaszewski, Jørgen F P, Jakobsen, A. H., Kiilerich, K., Hidalgo, J. & Pilegaard, Henriette, 2011, In: Acta Physiologica. 202, 2, p. 165-173 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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