Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity
Research output: Contribution to journal › Journal article › Research › peer-review
Insulin resistance induced by growth hormone (GH) is linked to promotion of lipolysis by unknown mechanisms. We hypothesized that suppression of the activity of pyruvate dehydrogenase in the active form (PDHa) underlies GH-induced insulin resistance similar to what is observed during fasting.
| Original language | English |
|---|---|
| Journal | Acta Physiologica |
| Volume | 210 |
| Issue number | 2 |
| Pages (from-to) | 392-402 |
| Number of pages | 11 |
| ISSN | 1748-1708 |
| DOIs | |
| Publication status | Published - 2014 |
ID: 63535152