Søren Tvorup Christensen

Søren Tvorup Christensen

Professor

ORCID: 0000-0001-5004-304X

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  1. Published

    A mechanism for growth arrest control in the primary cilium based on PDGR-alpha

    Schneider, L., Hoffmann, E. K., Satir, P. & Christensen, Søren Tvorup, 2003, In: Molecular Biology of the Cell. p. 323a

    Research output: Contribution to journal › Conference abstract in journal › Research

  2. A regulatory light chain of ciliary outer arm dynein in Tetrahymena thermophila

    Christensen, Søren Tvorup, Guerra, C., Wada, Y., Valentin, T., Angeletti, R. H., Satir, P. & Hamasaki, T., 2001, In: Journal of Biological Chemistry. 276, 23, p. 20048-54 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    ALMS1 Regulates TGF-β Signaling and Morphology of Primary Cilia

    Álvarez-Satta, M., Lago-Docampo, M., Bea-Mascato, B., Solarat, C., Castro-Sánchez, S., Christensen, Søren Tvorup & Valverde, D., 2021, In: Frontiers in Cell and Developmental Biology. 9, 8 p., 623829.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Activation of MAP Kinases upon hypertonic cell shrinkage in NIH3T3 Fibroblasts

    Nielsen, M., Christensen, Søren Tvorup & Hoffmann, E. K., 2004, In: Acta Physiologica (Print Edition). A45–A163, p. A108

    Research output: Contribution to journal › Conference abstract in journal › Research

  5. Published

    Analysis of caveolin in primary cilia

    Morthorst, Stine Kjær, Mogensen, J. B., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2020, Caveolae: Methods and Protocols. Blouin, C. M. (ed.). Humana Press, p. 27-41 (Methods in Molecular Biology, Vol. 2169).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  6. Published

    Analysis of primary cilia in directional cell migration in fibroblasts

    Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling

    Morthorst, Stine Kjær, Nielsen, C., Farinelli, P., Anvarian, Zeinab, Rasmussen, C. B. R., Serra-Marques, A., Grigoriev, I., Altelaar, M., Fürstenberg, N., Ludwig, A., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2022, In: Journal of Cell Science. 135, 12, 10 p., jcs259471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Apoptosis induced by hypertonicity-activation and nuclear translocation of the tumor suppressor p53 in NIH3T3-fibroblasts

    Schneider, L. & Christensen, Søren Tvorup, 2004, In: Acta Physiologica (Print Edition). A45–A163, p. A108

    Research output: Contribution to journal › Conference abstract in journal › Research

  9. Published

    Assembly of primary cilia.

    Pedersen, Lotte Bang, Veland, I. R., Schrøder, J. M. & Christensen, Søren Tvorup, 2008, In: Developmental Dynamics. 237, p. 1993-2006 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

    Gonçalves, A. B., Hasselbalch, S. K., Joensen, B. B., Patzke, S., Martens, P., Ohlsen, S. K., Quinodoz, M., Nikopoulos, K., Suleiman, R., Jeppesen, M. P. D., Weiss, C., Christensen, Søren Tvorup, Rivolta, C., Andersen, J. S., Farinelli, P. & Pedersen, Lotte Bang, 2021, In: eLife. 10, 34 p., e63731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine

    Christensen, S. L., Rasmussen, R. H., Ernstsen, C., La Cour, S., David, A., Chaker, J., Haanes, K. A., Christensen, Søren Tvorup, Olesen, Jes & Kristensen, D. M., 2021, In: Cephalalgia. 41, 14, p. 1413-1426 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells

    Nygaard, M. B., Almstrup, Kristian, Lindbæk, L., Christensen, Søren Tvorup & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Cell death, survival and proliferation in Tetrahymena thermophila. Effects of insulin, sodium nitroprusside, 8-Bromo cyclic GMP, NG-methyl-L-arginine and methylene blue

    Christensen, Søren Tvorup, Rasmussen, L., Kemp, K. & Quie, H., 1996, In: Cell Biology International. 20, 10, p. 653-66 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts.

    Friis, M. B., Friborg, C. R., Schneider, L., Nielsen, M., Lambert, Ian Henry, Christensen, Søren Tvorup & Hoffmann, E. K., 2005, In: Journal of Physiology. 567, 2, p. 427-43 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Cell shrinkage in NIH3T3-fibroblasts leads to activation of the stress-activated kinases p38, JNK and the transcription factor p53 followed by apoptosis

    Schneider, L., Nielsen, M., Christensen, Søren Tvorup & Hoffmann, E. K., 2003, In: Molecular Biology of the Cell. volume 14, p. 162a

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Cell signaling. A ciliary signaling switch

    Christensen, Søren Tvorup & Ott, C. M., 2007, In: Science. 317, 5836, p. 330-1 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Cell survival and multiplication. The overriding need for signals: from unicellular to multicellular systems

    Rasmussen, L., Christensen, Søren Tvorup, Schousboe, P. & Wheatley, D. N., 1996, In: FEMS Microbiology Letters. 137, 2-3, p. 123-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Cellular signalling by primary cilia in development, organ function and disease

    Anvarian, Zeinab, Mykytyn, K., Mukhopadhyay, S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2019, In: Nature Reviews Nephrology. 15, p. 199-219

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Chapter 10 the primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair

    Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Satir, P., Veland, I. R. & Schneider, L., 2008, In: Current Topics in Developmental Biology. 85, p. 261-301 40 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Characterization of an ex vivo femoral head model assessed by markers of bone and cartilage turnover

    Madsen, S. H., Goettrup, A. S., Thomsen, G., Christensen, Søren Tvorup, Schultz, N., Henriksen, K., Bay-Jensen, A. & Karsdal, M. A., 2011, In: Cartilage. 2, 3, p. 265-278 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines.

    Nielsen, S. K., Møllgård, Kjeld, Clement, C. A., Veland, I. R., Awan, A., Yoder, B. K., Novak, Ivana & Christensen, Søren Tvorup, 2008, In: Developmental Dynamics. 237, 8, p. 2039-52 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Cilia and coordination of signaling networks during heart development

    Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Cilia and flagella

    Schmid, F. M., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2016, Encyclopedia of cell biology. Bradshaw, R. A. & Stahl, P. D. (eds.). 1 ed. Elsevier, Vol. 2. p. 660-676 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research › peer-review

  26. Published

    Cilia and flagella

    Pedersen, Lotte Bang, Jurisch-Yaksi, N., Schmid, F. M. & Christensen, Søren Tvorup, 2023, Encyclopedia of Cell Biology, Second Edition. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Oxford: Elsevier, Vol. 3. p. 164-188 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  27. Published

    Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis

    Stevens, E. M., Vladar, E. K., Alanin, M. C., Christensen, Søren Tvorup, von Buchwald, Christian & Milla, C., Jan 2020, In: American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 120-123 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Comparative Proteome Bioinformatics: Identification of Phosphotyrosine Signaling Proteins in the Unicellular Protozoan Ciliate Tetrahymena

    Gammeltoft, S., Christensen, Søren Tvorup, Joachimiak, M., Hill, E., Guerra, C. F. & Satir, P., 2005, In: The FASEB Journal. Suppl., p. 785 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

    Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Compounds stimulating growth and multiplication in ciliates. Do also free-living cells release growth factors?

    Schousboe, P., Christensen, Søren Tvorup, Ghiladi, M. & Rasmussen, L., 1992, In: Die Naturwissenschaften. 79, 5, p. 234-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Compounds stimulating growth and multiplication in ciliates. Do also free-living cells release growth factors?

    Ghiladi, M., Christensen, Søren Tvorup, Schousboe, P. & Rasmussen, L., 1992, In: Die Naturwissenschaften. 79, 5, p. 234-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  33. Published

    Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts

    Schneider, L., Cammer, M., Lehman, J., Nielsen, S. K., Guerra, C. F., Veland, I. R., Stock, C., Hoffmann, E. K., Yoder, B. K., Schwab, A., Satir, P. & Christensen, Søren Tvorup, 2010, In: Cellular Physiology and Biochemistry. 25, 2-3, p. 279-92 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

    Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    EB1 is required for primary cilia assembly in fibroblasts.

    Schrøder, J. M., Schneider, L., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2007, In: Current Biology. 17, 13, p. 1134-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Early-stage apoptosis is associated with DNA-damage-independent ATM phosphorylation and chromatin decondensation in NIH3T3 fibroblasts.

    Schou, K. B., Schneider, L., Christensen, Søren Tvorup & Hoffmann, E. K., 2008, In: Cell Biology International. 32, 1, p. 107-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Editorial: Signaling by primary cilia in development and disease

    Kim, S. E., Nechipurenko, I. & Christensen, Søren Tvorup, 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1186367.

    Research output: Contribution to journal › Editorial › Research › peer-review

  38. Published

    Effects of osmotic stress on the activity of MAPKs and PDGFR-beta-mediated signal transduction in NIH-3T3 fibroblasts

    Nielsen, M., Christensen, Søren Tvorup & Hoffmann, E. K., 2008, In: American Journal of Physiology: Cell Physiology. 294, 4, p. C1046-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effects of osmotic stress on the activity of receptor tyrosine kinases and MAP kinases in NIH3T3-fibtoblasts

    Hoffmann, E. K., Nielsen, M. & Christensen, Søren Tvorup, 2004, In: Molecular Biology of the Cell. 15, p. 14a

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Effects of protein kinase C activators and staurosporine on protein kinase activity, cell survival, and proliferation in Tetrahymena thermophila.

    Straarup, E., Schousboe, P., Hansen, H., Kristiansen, K., Hoffmann, E. K., Rasmussen, L. & Christensen, Søren Tvorup, 1997, In: Microbios. 91, 368-369, p. 181-90

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Endocytic control of cellular signaling at the primary cilium

    Pedersen, Lotte Bang, Mogensen, J. B. & Christensen, Søren Tvorup, 2016, In: Trends in Biochemical Sciences. 41, 9, p. 784-797 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Evolution of protein kinases: Identification of tyrosine kinases in sensory cilia of tetrahymena

    Christensen, Søren Tvorup, Guerra, C. F., Awan, A., Valentin, T., Wheatley, D. N., Gammeltoft, S. & Satir, P., 2003, In: Molecular Biology of the Cell. vol. 14, p. 433a

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Evolutionary implications of localization of the signaling scaffold protein Parafusin to both cilia and the nucleus

    Satir, B. H., Wyroba, E., Liu, L., Lethan, M., Satir, P. & Christensen, Søren Tvorup, 2015, In: Cell Biology International. 39, 2, p. 136-145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Expression and localization of the progesterone receptor in mouse and human reproductive organs.

    Teilmann, S. C., Clement, C. A., Thorup, Jørgen Mogens, Byskov, A. G. & Christensen, Søren Tvorup, 2006, In: Journal of Endocrinology. 191, 3, p. 525-35 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Expression of genes and enzymes involved in ovarian steroidogenesis in relation to human follicular development

    Zheng, M., tcg964, tcg964, Rasmussen, F. R., Cadenas, J., Christensen, Søren Tvorup & Mamsen, L. S., 2023, In: Frontiers in Endocrinology. 14, 17 p., 1268248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia

    Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Glucocorticoids exert context-dependent effects on cells of the joint in vitro

    Madsen, S. H., Andreassen, K. V., Christensen, Søren Tvorup, Karsdal, M. A., Sverdrup, F. M., Bay-Jensen, A. & Henriksen, K., 2011, In: Steroids. 76, 13, p. 1474-82 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.

    Schneider, L., Klausen, T. K., Stock, C., Mally, S., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Schwab, A., 2008, In: Pflügers Archiv: European Journal of Physiology. 455, 6, p. 1055-62 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    High expression of the taurine transporter TauT in primary cilia of NIH3T3 fibroblasts

    Christensen, Søren Tvorup, Voss, J. W., Teilmann, S. C. & Lambert, Ian Henry, 2005, In: Cell Biology International. 29, 5, p. 347-351

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    High expression of the taurine transporter TauT in the primary cilium of NIH3T3 fibroblasts

    Voss, J. W., Christensen, Søren Tvorup, Lambert, Ian Henry & Teilmann, S. C., 2004, In: Molecular Biology of the Cell. vol. 15, p. 281a

    Research output: Contribution to journal › Journal article › Research › peer-review

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