Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium
Research output: Contribution to journal › Journal article › Research › peer-review
The presence of 10(-6) M bovine insulin in chemically defined nutrient medium prevented cell death and improved cell proliferation of the ciliate Tetrahymena pyriformis when inoculated at low initial cell density. The action of insulin was found to be restricted to the 22-30 fragment of the B-chain. These results suggest that small peptides are involved in regulation of cell survival and cell proliferation in Tetrahymena pyriformis.
Original language | English |
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Journal | Cell Biology International |
Volume | 17 |
Issue number | 9 |
Pages (from-to) | 833-7 |
Number of pages | 4 |
ISSN | 1065-6995 |
DOIs | |
Publication status | Published - 1993 |
Externally published | Yes |
Bibliographical note
Keywords: Amino Acid Sequence; Animals; Cattle; Cell Division; Culture Media, Serum-Free; Insulin; Molecular Sequence Data; Tetrahymena pyriformis
ID: 11256026