Unravelling interspecies interactions across heterogeneities in complex biofilm communities
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Unravelling interspecies interactions across heterogeneities in complex biofilm communities. / Røder, Henriette L.; Olsen, Nanna M. C.; Whiteley, Marvin; Burmølle, Mette.
In: Environmental Microbiology, Vol. 22, No. 1, 2020, p. 5-16.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Unravelling interspecies interactions across heterogeneities in complex biofilm communities
AU - Røder, Henriette L.
AU - Olsen, Nanna M. C.
AU - Whiteley, Marvin
AU - Burmølle, Mette
N1 - © 2019 Society for Applied Microbiology and John Wiley & Sons Ltd.
PY - 2020
Y1 - 2020
N2 - The importance of microbial biofilms has been well-recognized for several decades, and focus is now shifting towards investigating multispecies biofilm communities rather than mono- or dual-species biofilms. Therefore, the demand for techniques that provide a sufficient amount of information at adequate resolution is increasing. One major challenge for multispecies studies is that diversity and spatial organization often lead to a high degree of spatial and chemical heterogeneity. Many current approaches do not account for such heterogeneity and therefore only provide average information (-omics techniques in particular), which could obscure important information about the community. Here, we bring attention to the issues of heterogeneity when analysing synthetic multi-species biofilms, in vitro, and the importance of multi-scale approaches. We provide an overview of current and newer approaches that can be applied to biofilm communities, in order to elucidate interactions at the appropriate scale.
AB - The importance of microbial biofilms has been well-recognized for several decades, and focus is now shifting towards investigating multispecies biofilm communities rather than mono- or dual-species biofilms. Therefore, the demand for techniques that provide a sufficient amount of information at adequate resolution is increasing. One major challenge for multispecies studies is that diversity and spatial organization often lead to a high degree of spatial and chemical heterogeneity. Many current approaches do not account for such heterogeneity and therefore only provide average information (-omics techniques in particular), which could obscure important information about the community. Here, we bring attention to the issues of heterogeneity when analysing synthetic multi-species biofilms, in vitro, and the importance of multi-scale approaches. We provide an overview of current and newer approaches that can be applied to biofilm communities, in order to elucidate interactions at the appropriate scale.
U2 - 10.1111/1462-2920.14834
DO - 10.1111/1462-2920.14834
M3 - Review
C2 - 31637837
VL - 22
SP - 5
EP - 16
JO - Environmental Microbiology
JF - Environmental Microbiology
SN - 1462-2912
IS - 1
ER -
ID: 230141621