Jakob R. Winther
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- Published
Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water
Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Gersing, S. K., Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Visualization of nanofibrillar cellulose in biological tissues using a biotinylated carbohydrate binding module of β-1,4-Glycanase
Knudsen, K. B., Kofoed, Christian, Espersen, R., Højgaard, C., Winther, Jakob R., Willemoës, Martin, Wedin, I., Nuopponen, M., Vilske, S., Aimonen, K., Weydahl, I. E. K., Alenius, H., Norppa, H., Wolff, H., Wallin, E. H. R. & Vogel, U., 2015, In: Chemical Research in Toxicology. 28, 8, p. 1627-1635 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system
Koivisto, J. M., Poulsen, N. R., Larsen, B. S., Weibull, M. G. M., Stein, Amelie, Doro, F., Winther, Jakob R., Lindorff-Larsen, Kresten & Willemoës, Martin, 2022, In: The Biochemical journal. 479, 4, p. 479-501Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring the antigenic response to multiplexed immunizations in a chicken model of antibody production
Kousted, T. M., Kalliokoski, Otto, Christensen, S. K., Winther, Jakob R. & Hau, Jann, Mar 2017, In: Heliyon. 3, 3, 19 p., e00267.Research output: Contribution to journal › Journal article › Research › peer-review
The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix
Li, M., Phylip, L. H., Lees, W. E., Winther, Jakob R., Dunn, B. M., Wlodawer, A., Kay, J. & Gustchina, A., 2000, In: Nature Structural & Molecular Biology. 7, 2, p. 113-117 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Barley lipid transfer protein, LTP1, contains a new type of lipid-like post-translational modification
Lindorff-Larsen, K., Lerche, M. H., Poulsen, F. M., Roepstorff, P. & Winther, Jakob R., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33547-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Surprisingly high stability of barley lipid transfer protein, LTP1, towards denaturant, heat and proteases
Lindorff-Larsen, Kresten & Winther, Jakob R., 2001, In: FEBS Letters. 488, 3, p. 145-148 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Redox characteristics of the eukaryotic cytosol.
López-Mirabal, H. R. & Winther, Jakob R., 2007, In: BBA General Subjects.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations in the RAM network confer resistance to the thiol oxidant 4,4'-dipyridyl disulfide
López-Mirabal, H. R., Winther, Jakob R., Thorsen, M. & Kielland-Brandt, M. C., 2008, In: Molecular Genetics and Genomics. 279, 6, p. 629-42 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide.
López-Mirabal, H. R., Thorsen, M., Kielland-Brandt, M. C., Toledano, M. B. & Winther, Jakob R., 2007, In: FEMS Yeast Research. 7, 3, p. 391-403 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae.
López-Mirabal, H. R., Winther, Jakob R. & Kielland-Brandt, M. C., 2007, In: Bioscience, Biotechnology, and Biochemistry. 71, 12, p. 2934-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The thiol oxidant dipyridyl disulfide can supply the PDI-Ero1p pathway with additional oxidative equivalents.
López-Mirabal, H. R. & Winther, Jakob R., 2007, In: Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology. 92, 4, p. 463-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidant resistance in a yeast mutant deficient in the Sit4 phosphatase
López-Mirabal, H. R., Winther, Jakob R. & Kielland-Brandt, M. C., 2008, In: Current Genetics. 53, 5, p. 275-86 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic and thermodynamic properties of two barley thioredoxin h isozymes, HvTrxh1 and HvTrxh2
Maeda, K., Hägglund, Per Mårten, Björnberg, O., Winther, Jakob R. & Svensson, B., 2010, In: FEBS Letters. 584, 15, p. 3376-3380 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold
Marin, Frederikke Isa, Johansson, Kristoffer Enøe, O'Shea, Charlotte, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: The Journal of Physical Chemistry B. 125, 40, p. 11141-11149Research output: Contribution to journal › Journal article › Research › peer-review
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High-resolution imaging of redox signaling in live cells through an oxidation-sensitive yellow fluorescent protein
Maulucci, G., Labate, V., Mele, M., Panieri, E., Arcovito, G., Galeotti, T., Østergaard, H., Winther, Jakob R., De Spirito, M. & Pani, G., 2008, In: Science Signaling. 1, 43, p. pl3 1-15 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intracellular glutathione pools are heterogeneously concentrated
Montero, D., Tachibana, C., Winther, Jakob R. & Appenzeller-Herzog, C., 2013, In: Redox Biology. 1, 1, p. 508-513 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Production of a heterologous proteinase A by Saccharomyces kluyveri
Møller, K., Tidemand, L. D., Winther, Jakob R., Olsson, L., Piskur, J. & Nielsen, J., 2001, In: Applied Microbiology and Biotechnology. 57, 1-2, p. 216-219 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metal-ion dependent catalytic properties of Sulfolobus solfataricus class II α-mannosidase
Nielsen, J. W., Poulsen, N. R., Johnsson, A. M. S., Winther, Jakob R., Stipp, S. L. S. & Willemoës, Martin, 2012, In: Biochemistry. 51, 40, p. 8039-8046 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A fluorescent probe which allows highly specific thiol labeling at low pH
Nielsen, J. W., Jensen, K. S., Hansen, R. R. E., Gotfredsen, C. H. & Winther, Jakob R., 2012, In: Analytical Biochemistry. 421, 1, p. 115-120 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polysaccharide effects on calcite growth: the influence of composition and branching
Nielsen, J. W., Sand, Karina Krarup, Pedersen, C. S., Lakshtanov, L. Z., Winther, Jakob R., Willemoës, Martin & Stipp, S. L. S., 2012, In: Crystal Growth & Design. 12, 10, p. 4906-4910 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Trisulfides in Proteins
Nielsen, R. W., Tachibana, C., Hansen, N. E. & Winther, Jakob R., 2011, In: Antioxidants & Redox Signaling. 15, 1, p. 67-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increasing protein stability by inferring substitution effects from high-throughput experiments
Norrild, R. K., Johansson, Kristoffer Enøe, O'Shea, Charlotte, Morth, J. P., Lindorff-Larsen, Kresten & Winther, Jakob R., 2022, In: Cell Reports Methods. 2, 11, 11 p., 100333.Research output: Contribution to journal › Journal article › Research › peer-review
Gene regulation in response to protein disulphide isomerase deficiency
Nørgaard, P., Tachibana, C., Bruun, A. W. & Winther, Jakob R., 2003, In: Yeast. 20, 7, p. 645-652 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5143
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In Silico prediction of mutant HIV-1 proteases cleaving a target sequence
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270
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A soluble, folded protein without charged amino acid residues
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233
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Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
Research output: Contribution to journal › Journal article › Research › peer-review
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