Jakob R. Winther

Jakob R. Winther

Professor

ORCID: 0000-0001-6995-9154

Publication year:
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1 - 25 out of 109Page size: 25
  1. 2023
  2. Published

    Global analysis of multi-mutants to improve protein function

    Johansson, Kristoffer Enøe, Lindorff-Larsen, Kresten & Winther, Jakob R., 2023, In: Journal of Molecular Biology. 435, 8, 15 p., 168034.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2022
  4. Published

    Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system

    Koivisto, J. M., Poulsen, N. R., Larsen, B. S., Weibull, M. G. M., Stein, Amelie, Doro, F., Winther, Jakob R., Lindorff-Larsen, Kresten & Willemoës, Martin, 2022, In: The Biochemical journal. 479, 4, p. 479-501

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Engineering Bifidobacterium longum Endo-α-N-acetylgalactosaminidase for Neu5Acα2-3Ga1β1-3Ga1NAc reactivity on Fetuin

    Hansen, D. K., Hansen, A. L., Koivisto, J. M., Shuoker, B., Abou Hachem, M., Winther, Jakob R. & Willemoës, Martin, 2022, In: Archives of Biochemistry and Biophysics. 725, 8 p., 109280.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Increasing protein stability by inferring substitution effects from high-throughput experiments

    Norrild, R. K., Johansson, Kristoffer Enøe, O'Shea, Charlotte, Morth, J. P., Lindorff-Larsen, Kresten & Winther, Jakob R., 2022, In: Cell Reports Methods. 2, 11, 11 p., 100333.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The functional role of the autolysis loop in the regulation of factor X upon hemostatic response

    Bonde, A. C., Lund, J., Hansen, J. J., Winther, Jakob R., Nielsen, P. F., Zahn, S., Tiainen, P., Olsen, O. H., Petersen, H. H. & Rose Bjelke, J., 2022, In: Journal of Thrombosis and Haemostasis. 20, 3, p. 589-599 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2021
  9. Published

    Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry

    Abramsson, M. L., Sahin, C., Hopper, J. T. S., Branca, R. M. M., Danielsson, J., Xu, M., Chandler, S. A., Österlund, N., Ilag, L. L., Leppert, A., Costeira-Paulo, J., Lang, L., Teilum, K., Laganowsky, A., Benesch, J. L. P., Oliveberg, M., Robinson, C. V., Marklund, E. G., Allison, T. M., Winther, J. R. & 1 others, Landreh, M., 2021, In: JACS Au. 1, 12, p. 2385-2393 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Charge Interactions in a Highly Charge-Depleted Protein

    Hervø-Hansen, S., Højgaard, C., Johansson, Kristoffer Enøe, Wang, Y., Wahni, K., Young, D., Messens, J., Teilum, Kaare, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: Journal of the American Chemical Society. 143, 6, p. 2500-2508 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold

    Marin, Frederikke Isa, Johansson, Kristoffer Enøe, O'Shea, Charlotte, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: The Journal of Physical Chemistry B. 125, 40, p. 11141-11149

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Computational and experimental assessment of backbone templates for computational protein design

    Marin, Frederikke Isa, Johansson, K. E., O'Shea, Charlotte, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, 15 p.

    Research output: Working paper › Preprint › Research

  13. Published

    Flash properties of Gaussia luciferase are the result of covalent inhibition after a limited number of cycles

    Dijkema, F. M., Nordentoft, M. K., Didriksen, A. K., Corneliussen, A. S., Willemoës, Martin & Winther, Jakob R., 2021, In: Protein Science. 30, 3, p. 638-649 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Rational Protein Engineering to Increase the Activity and Stability of IsPETase Using the PROSS Algorithm

    Rennison, A., Winther, Jakob R. & Varrone, C., 2021, In: Polymers. 13, 22, 11 p., 3884.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Substitutional landscape of a split fluorescent protein fragment using high-density peptide microarrays

    Antonescu, O. N., Rasmussen, A., Damm, N. A. M., Heidemann, Ditte Fogh, Popov, R., Nesterov-Mueller, A., Johansson, Kristoffer Enøe & Winther, Jakob R., 2021, In: PLoS ONE. 16, 2, 17 p., e0241461.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water

    Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Andersen, Sarah Gersing, Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2019
  19. Published

    Improving folding properties of computationally designed proteins

    Bjerre, B., Nissen, J., Madsen, M., Kamarauskaite, J., Norrild, R. K., Holm, Peter Christoffer, Nordentoft, M. K., O'Shea, Charlotte, Willemoës, Martin, Johansson, Kristoffer Enøe & Winther, Jakob R., 13 Dec 2019, In: Protein Engineering Design and Selection (Print). 32, 3, p. 145-151 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Shining light on split fluorescent protein fitness landscapes using peptide array-based deep substitutional scanning

    ANTONESCU, O., Johansson, Kristoffer Enøe & Winther, Jakob R., 30 Jun 2019.

    Research output: Contribution to conference › Poster › Research › peer-review

  21. Published

    Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses

    Hadrup, N., Knudsen, K. B., Berthing, T., Wolff, H., Bengtson, S., Kofoed, Christian, Espersen, R., Højgaard, C., Winther, Jakob R., Willemoës, Martin, Wedin, I., Nuopponen, M., Alenius, H., Norppa, H., Wallin, H. & Vogel, U., 2019, In: Environmental Toxicology and Pharmacology. 66, p. 116-125 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Steady state kinetic analysis of O-linked GalNAc glycan release catalyzed by endo-α-N-acetylgalactosaminidase

    Hansen, D. K., Winther, Jakob R. & Willemoës, Martin, 2019, In: Carbohydrate Research. 480, p. 54-60

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2018
  24. Published

    Comprehensive mapping of GFP structure-function relationship using high-density peptide arrays

    Antonescu, O., Johansson, Kristoffer Enøe & Winther, Jakob R., 10 Jul 2018.

    Research output: Contribution to conference › Poster › Research › peer-review

  25. Published

    A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel

    Santner, P., Martins, J. M. D. S., Laursen, J. S., Behrendt, L., Riber, Leise, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5949-5956

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Can a Charged Surfactant Unfold an Uncharged Protein?

    Højgaard, C., Sørensen, H. V., Pedersen, J. S., Winther, Jakob R. & Otzen, D. E., 2018, In: Biophysical Journal. 115, 11, p. 2081-2086 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Editorial overview: A perspective on protein evolution

    Hoecker, B. & Winther, Jakob R., 2018, In: Current Opinion in Structural Biology. 48, p. viii-ix 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  28. Published

    Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month

    Ilves, M., Vilske, S., Aimonen, K., Lindberg, H. K., Pesonen, S., Wedin, I., Nuopponen, M., Vanhala, E., Højgaard, C., Winther, Jakob R., Willemoës, Martin, Vogel, U., Wolff, H., Norppa, H., Savolainen, K. & Alenius, H., 2018, In: Nanotoxicology. 12, 7, p. 729-746 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Protein evolution: Hacking an enzyme

    Johansson, Kristoffer Enøe & Winther, Jakob R., 2018, In: Nature Chemical Biology. 14, 3, p. 202-204 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  30. Published

    Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants

    Santner, P., Martins, J. M. D. S., Kampmeyer, Caroline, Hartmann-Petersen, Rasmus, Laursen, J. S., Stein, Amelie, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5957-5968

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2017
  32. Published

    Endoplasmic reticulum transport of glutathione by Sec61 is regulated by Ero1 and Bip

    Ponsero, A. J., Igbaria, A., Darch, M. A., Miled, S., Outten, C. E., Winther, Jakob R., Palais, G., D'Autréaux, B., Delaunay-Moisan, A. & Toledano, M. B., 21 Sep 2017, In: Molecular Cell. 67, 6, p. 962-973.e5 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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