Jakob R. Winther

Jakob R. Winther

Professor


  1. 1985
  2. Increased hydrophobicity of the S′1 binding site in carboxypeptidase Y obtained by site-directed mutagenesis

    Winther, Jakob R., Kielland-Brandt, M. C. & Breddam, K., 1985, In: Carlsberg Research Communications. 50, 5, p. 273-284 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1986
  4. Published

    Mutational replacement of methionine by arginine in the S′1 substrate binding site of yeast carboxypeptidase

    Bech, L. M., Nielsen, J., Winther, Jakob R., Kielland-Brandt, M. C. & Breddam, K., 1986, In: Carlsberg Research Communications. 51, 6, p. 459-465 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 1987
  6. Published

    THE FREE SULFHYDRYL-GROUP (CYS341) OF CARBOXYPEPTIDASE-Y - FUNCTIONAL-EFFECTS OF MUTATIONAL SUBSTITUTIONS

    WINTHER, J., BREDDAM, K. & Winther, Jakob R., 1987, In: Carlsberg Research Communications. 52, 4, p. 263-273

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 1990
  8. Published

    Yeast carboxypeptidase Y vacuolar targeting signal is defined by four propeptide amino acids

    Valls, L. A., Winther, Jakob R. & Stevens, T. H., 1990, In: Journal of Cell Biology. 111, 2, p. 361-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 1991
  10. Published

    Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity

    Winther, Jakob R. & Sørensen, P., 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 9330-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Yeast carboxypeptidase Y requires glycosylation for efficient intracellular transport, but not for vacuolar sorting, in vivo stability, or activity

    Winther, Jakob R., Stevens, T. H. & Kielland-Brandt, M., 1991, In: European Journal of Biochemistry. 197, 3, p. 681-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 1992
  13. Published

    Autoactivation of proteinase A initiates activation of yeast vacuolar zymogens

    van den Hazel, H. B., Kielland-Brandt, M. & Winther, Jakob R., 1992, In: European Journal of Biochemistry. 207, 1, p. 277-83 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 1993
  15. Published

    The pro region required for folding of carboxypeptidase Y is a partially folded domain with little regular structural core

    Sørensen, P., Winther, Jakob R., Kaarsholm, N. C. & Poulsen, F. M., 1993, In: Biochemistry. 32, 45, p. 12160-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The propeptide is required for in vivo formation of stable active yeast proteinase A and can function even when not covalently linked to the mature region

    van den Hazel, H. B., Kielland-Brandt, M. & Winther, Jakob R., 1993, In: Journal of Biological Chemistry. 268, 24, p. 18002-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 1994
  18. Published

    Active-site residues of procarboxypeptidase Y are accessible to chemical modification

    Sørensen, S. O. & Winther, Jakob R., 1994, In: BBA General Subjects. 1205, 2, p. 289-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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