Jakob R. Winther
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 1997
Active site mutations in yeast protein disulfide isomerase cause dithiothreitol sensitivity and a reduced rate of protein folding in the endoplasmic reticulum
Holst, B., Tachibana, C. & Winther, Jakob R., 1997, In: Journal of Cell Biology. 138, 6, p. 1229-1238 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism and ion-dependence of in vitro autoactivation of yeast proteinase A: possible implications for compartmentalized activation in vivo
Van Den Hazel, H., Wolff, A. M., Kielland-Brandt, M. & Winther, Jakob R., 1997, In: Biochemical Journal. 326 ( Pt 2), p. 339-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
A High-Affinity Inhibitor of Yeast Carboxypeptidase Y Is Encoded by TFS1 and Shows Homology to a Family of Lipid Binding Proteins
Bruun, A. W., Svendsen, I., Sørensen, S. O., Kielland-Brandt, M. C. & Winther, Jakob R., 1998, In: Biochemistry. 37, 10, p. 3351-3357 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic analysis of the mechanism and specificity of protein-disulfide isomerase using fluorescence-quenched peptides
Westphal, V., Spetzler, J. C., Meldal, Morten Peter, Christensen, U. & Winther, Jakob R., 1998, In: Journal of Biological Chemistry. 273, 39, p. 24992-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Preparation of fluorescence quenched libraries containing interchain disulphide bonds for studies of protein disulphide isomerases
Spetzler, J. C., Westphal, V., Winther, Jakob R. & Meldal, M., 1998, In: Journal of Peptide Science. 4, 2, p. 128-137 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
Functional properties of the two redox-active sites in yeast protein disulphide isomerase in vitro and in vivo
Westphal, V., Darby, N. J. & Winther, Jakob R., 1999, In: Journal of Molecular Biology. 286, 4, p. 1229-1239 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae
Jørgensen, M. U., Emr, S. D. & Winther, Jakob R., 1999, In: European Journal of Biochemistry. 260, 2, p. 461-469 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation: prime suspect found 'not guilty'
Bader, M., Winther, Jakob R. & Bardwell, J. C. A., 1999, In: Nature Cell Biology. 1, 3, p. E57-E58Research output: Contribution to journal › Comment/debate › Communication
- 2000
- Published
Purification, co-crystallization and preliminary X-ray analysis of the natural aspartic proteinase inhibitor I(A)3 complexed with saccharopepsin from Saccharomyces cerevisiae
Badasso, M. O., Read, J. A., Dhanaraj, V., Cooper, J. B., Wood, S. P., Blundell, T. L., Dreyer, T. & Winther, Jakob R., 2000, In: Acta Crystallographica Section D: Biological Crystallography.Research output: Contribution to journal › Journal article › Research › peer-review
The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix
Li, M., Phylip, L. H., Lees, W. E., Winther, Jakob R., Dunn, B. M., Wlodawer, A., Kay, J. & Gustchina, A., 2000, In: Nature Structural & Molecular Biology. 7, 2, p. 113-117 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5143
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In Silico prediction of mutant HIV-1 proteases cleaving a target sequence
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A soluble, folded protein without charged amino acid residues
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Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
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