Jakob R. Winther
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 1994
- Published
Active-site residues of procarboxypeptidase Y are accessible to chemical modification
Sørensen, S. O. & Winther, Jakob R., 1994, In: BBA General Subjects. 1205, 2, p. 289-93 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refolding of a carboxypeptidase Y folding intermediate in vitro by low-affinity binding of the proregion
Winther, Jakob R., Sørensen, P. & Kielland-Brandt, M., 1994, In: Journal of Biological Chemistry. 269, 35, p. 22007-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Requirement of the propeptide for in vivo formation of active yeast carboxypeptidase Y
Ramos, C., Winther, Jakob R. & Kielland-Brandt, M., 1994, In: Journal of Biological Chemistry. 269, 9, p. 7006-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH-dependent processing of yeast procarboxypeptidase Y by proteinase A in vivo and in vitro
Sørensen, S. O., van den Hazel, H. B., Kielland-Brandt, M. & Winther, Jakob R., 1994, In: European Journal of Biochemistry. 220, 1, p. 19-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
The pro region required for folding of carboxypeptidase Y is a partially folded domain with little regular structural core
Sørensen, P., Winther, Jakob R., Kaarsholm, N. C. & Poulsen, F. M., 1993, In: Biochemistry. 32, 45, p. 12160-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The propeptide is required for in vivo formation of stable active yeast proteinase A and can function even when not covalently linked to the mature region
van den Hazel, H. B., Kielland-Brandt, M. & Winther, Jakob R., 1993, In: Journal of Biological Chemistry. 268, 24, p. 18002-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
Autoactivation of proteinase A initiates activation of yeast vacuolar zymogens
van den Hazel, H. B., Kielland-Brandt, M. & Winther, Jakob R., 1992, In: European Journal of Biochemistry. 207, 1, p. 277-83 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity
Winther, Jakob R. & Sørensen, P., 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 9330-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Yeast carboxypeptidase Y requires glycosylation for efficient intracellular transport, but not for vacuolar sorting, in vivo stability, or activity
Winther, Jakob R., Stevens, T. H. & Kielland-Brandt, M., 1991, In: European Journal of Biochemistry. 197, 3, p. 681-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
Yeast carboxypeptidase Y vacuolar targeting signal is defined by four propeptide amino acids
Valls, L. A., Winther, Jakob R. & Stevens, T. H., 1990, In: Journal of Cell Biology. 111, 2, p. 361-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5143
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In Silico prediction of mutant HIV-1 proteases cleaving a target sequence
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A soluble, folded protein without charged amino acid residues
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Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
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